Results 21 to 30 of about 111,107 (240)
A Review on the Molecular Pathology of Epithelial Thyroid Tumors
Epithelial thyroid tumors are all from the thyrocytes, the follicular epithelial cells of the thyroid. If these cells do not replicate the normal mechanisms of growth, cell division, and apoptosis, and enter to the uncontrolled growth phase, thyroid ...
Seyedeh Adeleh Razavi +3 more
doaj +1 more source
La trasparenza nei rapporti banca - cliente [PDF]
Il capitolo esamina le regole che disciplinano le relazioni banca - cliente in materia di pubblicità e informazioni precontrattuale, contratti, modifica unilaterale delle condizioni, comunicazioni alla clientela, modalità di calcolo degli interessi e ...
Antonio Proto
core
Dynamical Behaviour of a Time Delay Model of the ERK and STAT5 Interaction [PDF]
In this paper we have done sensitive analysis of a time delay model which describes the ERK and STAT5 interaction. The results show that the type of the equilibrium point of the model can be a compound saddle-focus or a compound saddle-knot.
Kotev V.
doaj
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
OBJETIVO: Comparar a expressão gênica (mRNA) e protéica dos protooncogenes c-fos, c-myc e c-jun em miométrio normal e mioma humanos. MÉTODOS: Foi realizado um estudo do tipo caso-controle.
Ana Luiza Ferrari +6 more
doaj +1 more source
Repeat-element driven activation of proto-oncogenes in human malignancies
Recent data demonstrated that the aberrant activity of endogenous repetitive elements of the DNA in humans can drive the expression of proto-oncogenes.
Björn Lamprecht +8 more
core +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Proto-Industrialization? Cottage Industry, Social Change, and Industrial Revolution
Proto-Industrialization?
Rab Houston (7594109) +1 more
core +6 more sources
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source

