Results 21 to 30 of about 57,684 (329)
Transformation Locked in a Loop [PDF]
, 2009 During neoplastic transformation, cells can promote their own growth by activating proto-oncogenes. Reporting in Cell, Iliopoulos et al. (2009) now show that in certain cell types, a transient oncogenic signal is sufficient to induce neoplastic ...
Agami, Reuven, Drost, Jarno
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PBF, a proto-oncogene in esophageal carcinoma [PDF]
Open Medicine, 2019 Abstract Emerging evidence shows that the pituitary tumour-transforming gene (PTTG)-binding factor (PBF) functions as a proto-oncogene in some tumors. However, the precise functions of PBF in tumorigenesis and its action mechanisms remain largely unknown.
Yi Huang, Jun-ding Song, Shi-hai Lian
openaire +4 more sources
Importância do vírus da leucemia felina na linfomagênese: Revisão
Pubvet, 2018 O vírus da Leucemia felina (FeLV) é um retrovírus oncogênico frequentemente relacionado ao linfoma em felinos domésticos. O principal mecanismo pelo qual o FeLV induz neoplasia é através da mutagênese insercional adquirida somaticamente, podendo o ...
Dayse Helena Lages da Silva +3 more
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Lung Cancer: A Literature Review
Jurnal Respirasi, 2023 Lung cancer is a cancer whose onset starts in the lungs where there is an abnormal cell growth that is very fast and uncontrolled. The abnormal cell growth is triggered by deoxyribonucleic acid (DNA) damage, including deletions in the DNA section ...
Yan Efrata Sembiring +8 more
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O PROTO-ONCOGENE RAS NO BÓCIO MULTINODULAR
Clinical and Biomedical Research, 2022 A transformação neoplásica resulta de uma série de alterações genéticas, envolvendo ativação de proto-oncogenes e inativação de genes supressores tumorais.
Lenara Golbert +5 more
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Human Gene Control by Vital Oncogenes: Revisiting a Theoretical Model and Its Implications for Targeted Cancer Therapy [PDF]
, 2011 An important assumption of our current understanding of the mechanisms of carcinogenesis has been the belief that clarification of the cancer process would inevitably reveal some of the crucial mechanisms of normal human gene regulation.
Willis, Rudolph E.
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Role of Proto-Oncogene Activation in Carcinogenesis [PDF]
Environmental Health Perspectives, 1992 The accumulation of genetic damage in the forms of activated proto-oncogenes and inactivated tumor-suppressor genes is the driving force in the evolution of a normal cell to a malignant cell. For example, both the activation of ras oncogenes and the inactivation of several suppressor genes, including p53, have been observed in the development of human ...
Robert M. Maronpot +3 more
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A Review on the Molecular Pathology of Epithelial Thyroid Tumors
مجله دانشکده پزشکی اصفهان, 2018 Epithelial thyroid tumors are all from the thyrocytes, the follicular epithelial cells of the thyroid. If these cells do not replicate the normal mechanisms of growth, cell division, and apoptosis, and enter to the uncontrolled growth phase, thyroid ...
Seyedeh Adeleh Razavi +3 more
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Functional Polymorphisms Associated with Disease-Free Survival in Resected Carcinoma of the Esophagus [PDF]
, 2010 Purpose: The aim of this study was to determine whether clinical outcome after surgical resection of esophageal adenocarcinoma (EAC) or esophageal squamous cell carcinoma (ESCC) could be predicted by functional polymorphisms in different proto-oncogenes ...
A Ewart-Toland +30 more
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Detection of Mutations in Selected Proto-Oncogenes of Canine Lymphoma
Folia Veterinaria, 2017 Lymphomas belong among the most frequently diagnosed tumours of the haematopoietic system in dogs. The clinical manifestations and genetic and molecular basis of canine lymphoma resembles those of human non-Hodgkin lymphoma and therefore it can serve as ...
Bóna G., Šiviková K.
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