Results 71 to 80 of about 5,394 (238)
The Role of CREB as a Proto-oncogene in Hematopoiesis [PDF]
, 2005 Kentaro Kinjo +3 more
openalex +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Expression of the c-mpl proto-oncogene in human hematologic malignancies [PDF]
, 1993 Isabelle Vigon +7 more
openalex +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Diagnostic Biomarkers Related to Cancer Detection and Treatment: A Review Article
مجلة علوم ذي قار, 2021 Cancer is a serious problem affecting the health of all human societies. Thus the challenge is how the diagnosis and then who find effective treatment. Proto-oncogenes under abnormal condition turn out to be oncogenes throughout genetic mutation, which ...
.Suhad Faisal Hatem Al-Mugdadi
doaj
Proto-Oncogene Ets-1 and the Kidney [PDF]
, 2001 Mohammed S. Razzaque +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Supplementary Figure 4 from PNUTS Functions as a Proto-Oncogene by Sequestering PTEN [PDF]
, 2023 Sridhar Kavela +12 more
openalex +2 more sources
Repurposing of US-FDA-approved drugs as negative modulators of ubiquitin specific protease-7 (USP7)
HeliyonUbiquitin-specific protease7 (USP7) regulates the stability of the p53 tumor suppressor protein and several other proteins critical for tumor cell survival.
Seema Zadi +6 more
doaj +1 more source