Results 1 to 10 of about 4,711 (225)

A Fusion–Growth Protocell Model Based on Vesicle Interactions with Pyrite Particles [PDF]

Molecules
Protocell models play a pivotal role in the exploration of the origin of life. Vesicles are one type of protocell model that have attracted much attention.
Dong Guo, Ziyue Zhang, Jichao Sun, Hui Zhao, Wanguo Hou, Na Du   +5 more
doaj   +4 more sources

Nanoporous Silica-Based Protocells at Multiple Scales for Designs of Life and Nanomedicine [PDF]

Life, 2015
Various protocell models have been constructed de novo with the bottom-up approach. Here we describe a silica-based protocell composed of a nanoporous amorphous silica core encapsulated within a lipid bilayer built by self-assembly that provides for ...
Jie Sun, Eric Jakobsson, Yingxiao Wang, C. Jeffrey Brinker   +3 more
doaj   +4 more sources

The evolutionary dynamics of metabolic protocells. [PDF]

PLoS Computational Biology, 2018
Protocell multilevel selection models have been proposed to study the evolutionary dynamics of vesicles encapsulating a set of replicating, competing and mutating sequences.
Ximo Pechuan, Raymond Puzio, Aviv Bergman   +2 more
doaj   +3 more sources

A model of protocell based on the introduction of a semi-permeable membrane in a stochastic model of catalytic reaction networks [PDF]

Electronic Proceedings in Theoretical Computer Science, 2013
In this work we introduce some preliminary analyses on the role of a semi-permeable membrane in the dynamics of a stochastic model of catalytic reaction sets (CRSs) of molecules. The results of the simulations performed on ensembles of randomly generated
Marco Villani, Chiara Damiani, Alex Graudenzi, Alessandro Filisetti, Roberto Serra   +4 more
doaj   +6 more sources

Toward homochiral protocells in noncatalytic peptide systems [PDF]

, 2009
The activation-polymerization-epimerization-depolymerization (APED) model of Plasson et al. has recently been proposed as a mechanism for the evolution of homochirality on prebiotic Earth.
A Brack, A Brandenburg, A Brandenburg, A Commeyras, A Lazcano, B-M Rode, C Shen, C Viedma, CJ Welch, D Castelvecchi, D Deamer, D Deamer, D Deamer, D Segrè, D-G Blackmond, D-K Kondepudi, F-C Frank, G Wächtershäuser, G-F Joyce, G-F Joyce, H-J Morowitz, J-A Wattis, J-D Gunton, J-S Langer, J-W Szostak, JD Dunitz, K Soai, L Leman, M Fishkis, M Gleiser, M Gleiser, M Gleiser, M Huber, M Huber, M Reches, M Reches, M-P Robertson, Marcelo Gleiser, N Berclaz, N Berclaz, P-A Monnard, P-G-H Sandars, R Cotterill, R Lathe, R Lathe, R Plasson, R-M Smith, R-P Bywater, S Fox, S Fox, S Fox, S Lonchin, S Rasmussen, S Santoso, S Vauthey, S-L Miller, Sara Imari Walker, UJ Meierhenrich, V-A Avetisov, W-A Bonner, Y Saito, Y Saito   +61 more
core   +2 more sources

Multistable Protocells Can Aid the Evolution of Prebiotic Autocatalytic Sets [PDF]

Life, 2023
We present a simple mathematical model that captures the evolutionary capabilities of a prebiotic compartment or protocell. In the model, the protocell contains an autocatalytic set whose chemical dynamics is coupled to the growth–division dynamics of ...
Angad Yuvraj Singh, Sanjay Jain
doaj   +2 more sources

On the Growth Rate of Non-Enzymatic Molecular Replicators [PDF]

Entropy, 2011
It is well known that non-enzymatic template directed molecular replicators X + nO -> 2X exhibit parabolic growth d[X]/dt -> k[X]1/2. Here, we analyze the dependence of the effective replication rate constant k on hybridization energies ...
Harold Fellermann, Steen Rasmussen
doaj   +5 more sources

Enzymatically reconfigurable liquid crystalline coacervate microdroplets as protocell models [PDF]

Nature Communications
Reconfigurable cell-sized compartments can act as artificial cellular models that dynamically respond to environmental stimuli, mimicking the adaptive behaviors of living cells.
Liyan Jia, Chengcheng Zhou, Yan Qiao
doaj   +2 more sources

Recent advances in coacervate protocells from passive catalysts to chemically programmable systems [PDF]

Communications Chemistry
This review highlights a clear change in focus in the study of coacervate droplets as protocell models, moving from their role as passive microreactors that concentrate reactants to their function as chemically programmable matter capable of information ...
Chong Chen, Jianwei Li
doaj   +2 more sources

Sugar‐sensing swodkoreceptors and swodkocrine signaling [PDF]

Animal Models and Experimental Medicine
Sugars are one of the major metabolites and are essential for nucleic acid synthesis and energy production. In addition, sugars can act as signaling molecules.
Savani Anbalagan
doaj   +2 more sources