Results 101 to 110 of about 5,052 (178)

Conjecture and hypothesis: The importance of reality checks

open access: yesBeilstein Journal of Organic Chemistry, 2017
In origins of life research, it is important to understand the difference between conjecture and hypothesis. This commentary explores the difference and recommends alternative hypotheses as a way to advance our understanding of how life can begin on the ...
David Deamer
doaj   +1 more source

Coupled Phases and Combinatorial Selection in Fluctuating Hydrothermal Pools: A Scenario to Guide Experimental Approaches to the Origin of Cellular Life

open access: yesLife, 2015
Hydrothermal fields on the prebiotic Earth are candidate environments for biogenesis. We propose a model in which molecular systems driven by cycles of hydration and dehydration in such sites undergo chemical evolution in dehydrated films on mineral ...
Bruce Damer, David Deamer
doaj   +1 more source

Compartmentalization and Cell Division through Molecular Discreteness and Crowding in a Catalytic Reaction Network

open access: yesLife, 2014
Explanation of the emergence of primitive cellular structures from a set of chemical reactions is necessary to unveil the origin of life and to experimentally synthesize protocells.
Atsushi Kamimura, Kunihiko Kaneko
doaj   +1 more source

From inanimate matter to living systems [PDF]

open access: yes
Since the early part of this century, the Genesis account of the origin and evolution of life has been explained as an extrapolation of astronomical and geochemical processes.
Fox, S. W.
core   +1 more source

Avenues for emergent ecologies

open access: yes, 2013
In this work, we present some fascinating behaviour emerging from a simple synthetic chemistry model. The results of Ono and Ikegami (2001) demonstrated the spontaneous formation of primitive, self-reproducing cells from a random homogeneous mixture of ...
Bartlett, Stuart, Bullock, Seth
core  

On Protocell "Computation" [PDF]

open access: yes, 2006
The EU FP6 Integrated Project PACE ('Programmable Artificial Cell Evolution') is investigating the creation, de novo, of chemical 'protocells'. These will be minimal 'wetware' chemical systems integrating molecular information carriers, primitive energy conversion (metabolism) and containment (membrane).
Kelly, Ciarán   +2 more
openaire  

Framing major prebiotic transitions as stages of protocell development: three challenges for origins-of-life research

open access: yesBeilstein Journal of Organic Chemistry, 2017
Conceiving the process of biogenesis as the evolutionary development of highly dynamic and integrated protocell populations provides the most appropriate framework to address the difficult problem of how prebiotic chemistry bridged the gap to full ...
Ben Shirt-Ediss   +2 more
doaj   +1 more source

Silicasomes in Oncology: From Conventional Chemotherapy to Combined Immunotherapy

open access: yesMolecules
The use of nanoparticles as drug carriers in oncology has evolved from their traditional role as chemotherapy carriers to their application in immunotherapy, exploiting not only their passive accumulation in solid tumors but also their ability to ...
Alicia Arroyo-Nogales   +4 more
doaj   +1 more source

Protocells: Subcompartmentalization and Pseudo‐Division of Model Protocells (Small 2/2021) [PDF]

open access: yesSmall, 2021
Karolina Spustova   +3 more
openaire   +1 more source

Membranous Protocell Superstructures

open access: yes, 2021
How primitive cells emerged and developed on the early Earth remain an unsolved question. In contrast to the hypotheses that the first living cells evolved from a single ancestor, their development as colonies would provide numerous advantages, such as mechanical stability, enhancement of chemical reactions, and sharing of prebiotic molecules.
openaire   +2 more sources

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