Results 81 to 90 of about 3,247 (202)
ChemSystemsChem, Volume 8, Issue 4, July 2026.POPG‐containing membranes reduce leakage during freeze–thaw fusion, enabling efficient multi‐component delivery and protein synthesis inside GUVs. ABSTRACT Fusion between giant unilamellar vesicles (GUVs) provides a simple way to deliver and mix biochemical substrates within compartments surrounded by phospholipid membrane.
Tsubasa Yamashina +2 more
wiley +1 more source
Tuning interfacial fluidity and colloidal stability of membranized coacervate protocells
Communications ChemistryThe cell membrane not only serves as the boundary between the cell’s interior and the external environment but also plays a crucial role in regulating fundamental cellular behaviours. Interfacial membranization of membraneless coacervates, formed through
Yanglimin Ji, Yan Qiao
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Nanosilica-supported liposome (protocells) as a drug vehicle for cancer therapy
International Journal of Nanomedicine, 2018 Vinay K Belwal,1 KP Singh1,2 1Bio-Nanotechnology Research Laboratory, Biophysics Unit, CBSH, GB Pant University Agriculture and Technology, Pantnagar, Uttarakhand, 2Department of Molecular Biology, Biotechnology & Bioinformatics, COBSH, CCS Haryana ...
Belwal VK, Singh KP
doaj
Let There be Light! Light as an Engine and Regulator in Synthetic Cells
Angewandte Chemie International Edition, Volume 65, Issue 24, 8 June 2026.Cells are out‐of‐equilibrium systems that regulate their spatiotemporal features. In biomimetic synthetic cells, light offers a unique way for energizing and regulating events in space and time. This review explores the implementation of light‐responsive tools in synthetic cells to replicate biological functions and enable new bioinspired behaviors ...
Matthew E. Allen +5 more
wiley +1 more source
The Polymers of Life: Exploring Cellular Function Through Polymer Concepts
Advanced Science, Volume 13, Issue 33, 15 June 2026.Biomolecular phase separation reveals that a hidden layer of cellular organization is governed by the principles of polymer science. This review bridges polymer physics and cell biology, offering a primer on fundamental concepts, proposing a framework for interrogating cellular function, and synthesizing biophysical methods for decoding macromolecular ...
Mark Chen, Ashutosh Chilkoti
wiley +1 more source
ChemNanoMat, Volume 12, Issue 6, June 2026.Stimuli‐responsive strategies to achieve controlled release of protein‐based therapeutic agents into solid tumors. Proteins, enzymes, and peptides have long been recognized as valuable therapeutic agents, particularly in oncology. However, their complex chemical structures render them more sensitive than smaller chemotherapeutic drugs.
Guillermo Plaza‐Palomo +3 more
wiley +1 more source
Nature CommunicationsThe bottom-up reconstitution of self-growing artificial cells is a critical milestone toward realizing autonomy and evolvability. However, building artificial cells that exhibit self-growth coupled with internal replication of gene-encoding DNA has not ...
Yoshihiro Minagawa +3 more
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Evolution and self-assembly of protocells [PDF]
The International Journal of Biochemistry & Cell Biology, 2009 Cells define the minimal building blocks of life. How cellular life emerged and evolved implies to cross the boundary between living and nonliving matter. Here we explore this problem by presenting several relevant components of the whole picture involving chemistry, physics and natural selection.
openaire +2 more sources
Conjecture and hypothesis: The importance of reality checks
Beilstein Journal of Organic Chemistry, 2017 In origins of life research, it is important to understand the difference between conjecture and hypothesis. This commentary explores the difference and recommends alternative hypotheses as a way to advance our understanding of how life can begin on the ...
David Deamer
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Life, 2015 Hydrothermal fields on the prebiotic Earth are candidate environments for biogenesis. We propose a model in which molecular systems driven by cycles of hydration and dehydration in such sites undergo chemical evolution in dehydrated films on mineral ...
Bruce Damer, David Deamer
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