Results 101 to 110 of about 3,247 (202)
Multi-Armed Droplets as Shape-Changing Protocells
, 2018 Protocells are objects that mimic one or several functions of biological cells and may be embodied as solid particles, lipid vesicles, or droplets. Our work is based on using decanol droplets in an aqueous solution of sodium decanoate in the presence of
Jitka Čejková +2 more
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Silicasomes in Oncology: From Conventional Chemotherapy to Combined Immunotherapy
MoleculesThe use of nanoparticles as drug carriers in oncology has evolved from their traditional role as chemotherapy carriers to their application in immunotherapy, exploiting not only their passive accumulation in solid tumors but also their ability to ...
Alicia Arroyo-Nogales +4 more
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Photoreceptor-Like Signal Transduction Between Polymer-Based Protocells [PDF]
Deciphering inter- and intracellular signaling pathways is pivotal for understanding the intricate communication networks that orchestrate life's dynamics.
Korpidou, Maria +9 more
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, 2018 Encapsulation of structurally and functionally intact chloroplasts within coacervate micro-droplets is used to prepare photosynthetically active membrane-free protocells.
Stephen Mann +6 more
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On the nature of the earliest known lifeforms
eLifeMicrofossils from the Paleoarchean Eon are the oldest known evidence of life. Despite their significance in understanding the history of life on Earth, any interpretation of the nature of these microfossils has been a point of contention among ...
Dheeraj Kanaparthi +8 more
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Evolving protocells to prototissues: rational design of a missing link
, 2013 Realization of a functional artificial cell, the so-called protocell, is a major challenge posed by synthetic biology. A subsequent goal is to use the protocellular units for the bottom-up assembly of prototissues.
Sapra, K. Tanuj +3 more
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Non-Equilibrium Thermodynamics of Self-Replicating Protocells
, 2015 We provide a non-equilibrium thermodynamic description of the life-cycle of a droplet based, chemically feasible, system of protocells. By coupling the protocells metabolic kinetics with its thermodynamics, we demonstrate how the system can be driven out
Fellermann, Harold +5 more
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How Strong Is the Case for the RNA World?
LifeThe RNA World theory was proposed as a way to explain the origin of the DNA-RNA-Protein relationship found all current cells. It has been greatly strengthened by experimental work on ribozymes and non-enzymatic replication, and has become the most widely
Paul G. Higgs
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THE ETHICS OF PROTOCELLS: MORAL AND SOCIAL IMPLICATIONS OF CREATING LIFE IN THE LABORATORY
, 2009 Series foreword -- Preface -- 1. Introduction to the ethics of protocells / Mark A. Bedau and Emily C. Parke -- I. Risk, uncertainty, and precaution with protocells -- 2. New technologies, public perceptions, and ethics / Brian Johnson -- 3.
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Molecular Dynamics Unveils the Emergence of Dividing Protocells from Self-Replicating RNA
The origin of life requires self-replicating molecules to evolve into dividing pro?tocells. We used molecular dynamics (MD) to simulate this transition across four phases: self-replicating RNA, RNA-peptide-membrane complexes, metabolism-driven protocells,
Kaisheng Li
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