Results 101 to 110 of about 5,117 (196)

The evolutionary dynamics of metabolic protocells

open access: yesPLOS Computational Biology, 2018
Protocell multilevel selection models have been proposed to study the evolutionary dynamics of vesicles encapsulating a set of replicating, competing and mutating sequences. The frequency of the different sequence types determines protocell survival through a fitness function.
Ximo Pechuan   +2 more
openaire   +4 more sources

The origin of biological macromolecules on the earth. The hypothesis of inorganic template [PDF]

open access: yes
Studies about the origin of life are reviewed. The nonrandom organization of organelles is discussed from a structural and functional point of view. After postulating that the origin of biomacromolecules was not a random event, the paper develops the ...
Lu, T. S.
core   +1 more source

Framing major prebiotic transitions as stages of protocell development: three challenges for origins-of-life research

open access: yesBeilstein Journal of Organic Chemistry, 2017
Conceiving the process of biogenesis as the evolutionary development of highly dynamic and integrated protocell populations provides the most appropriate framework to address the difficult problem of how prebiotic chemistry bridged the gap to full ...
Ben Shirt-Ediss   +2 more
doaj   +1 more source

Silicasomes in Oncology: From Conventional Chemotherapy to Combined Immunotherapy

open access: yesMolecules
The use of nanoparticles as drug carriers in oncology has evolved from their traditional role as chemotherapy carriers to their application in immunotherapy, exploiting not only their passive accumulation in solid tumors but also their ability to ...
Alicia Arroyo-Nogales   +4 more
doaj   +1 more source

A four-track perspective for bottom-up synthetic cells

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Pasquale Stano
doaj   +1 more source

Conditions for emergent synchronization in protocells

open access: yes, 2007
A major aspect of the dynamics of a populations of protocells, is that, in order to assure sustainable growth, the genetic material and container productions must be synchronized if they are coupled. In a previous work [10] we have shown that such synchronization is an emergent property in many relevant protocell models, assuming both linear and ...
SERRA, Roberto   +4 more
openaire   +3 more sources

Coacervate droplets as pH-regionalized protocells. [PDF]

open access: yesNat Commun
Wang C   +4 more
europepmc   +1 more source

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