Results 121 to 130 of about 1,827,802 (158)

Identification of an Extracellular Gate for the Proton-coupled Folate Transporter (PCFT-SLC46A1) by Cysteine Cross-linking. [PDF]

J Biol Chem, 2016
Zhao R, Najmi M, Fiser A, Goldman ID.
europepmc   +1 more source

Evaluation of proton-coupled folate transporter (SLC46A1) polymorphisms as risk factors for neural tube defects and oral clefts. [PDF]

Am J Med Genet A, 2016
VanderMeer JE, Carter TC, Pangilinan F, Mitchell A, Kurnat-Thoma E, Kirke PN, Troendle JF, Molloy AM, Munger RG, Feldkamp ML, Mansilla MA, Mills JL, Murray JC, Brody LC.   +13 more
europepmc   +1 more source

Residues in the eighth transmembrane domain of the proton-coupled folate transporter (SLC46A1) play an important role in defining the aqueous translocation pathway and in folate substrate binding. [PDF]

Biochim Biophys Acta Biomembr, 2017
Aluri S, Zhao R, Fiser A, Goldman ID.
europepmc   +1 more source

Fluorine-Substituted Pyrrolo[2,3- d]Pyrimidine Analogues with Tumor Targeting via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis. [PDF]

J Med Chem, 2018
Ravindra M, Wilson MR, Tong N, O'Connor C, Karim M, Polin L, Wallace-Povirk A, White K, Kushner J, Hou Z, Matherly LH, Gangjee A.   +11 more
europepmc   +1 more source

Dual Targeting of Epithelial Ovarian Cancer Via Folate Receptor α and the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3-d]pyrimidine Antifolates. [PDF]

Mol Cancer Ther, 2017
Hou Z, Gattoc L, O'Connor C, Yang S, Wallace-Povirk A, George C, Orr S, Polin L, White K, Kushner J, Morris RT, Gangjee A, Matherly LH.   +12 more
europepmc   +1 more source

Tumor Targeting with Novel Pyridyl 6-Substituted Pyrrolo[2,3- d]Pyrimidine Antifolates via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of De Novo Purine Nucleotide Biosynthesis. [PDF]

J Med Chem, 2018
Ravindra M, Wallace-Povirk A, Karim MA, Wilson MR, O'Connor C, White K, Kushner J, Polin L, George C, Hou Z, Matherly LH, Gangjee A.   +11 more
europepmc   +1 more source

[Hereditary folate malabsorption due to an SLC46A1 mutation with cerebral folate deficiency and refractory epilepsy: first case reported in Argentina] [PDF]

Rev Fac Cien Med Univ Nac Cordoba
Grosso CL, Peralta LV, Paviolo M, Pautasso J, Guelbert GA, Bovina Martijena MDP, Laróvere LE.   +6 more
europepmc   +1 more source

CSF 5-Methyltetrahydrofolate Serial Monitoring to Guide Treatment of Congenital Folate Malabsorption Due to Proton-Coupled Folate Transporter (PCFT) Deficiency. [PDF]

JIMD Rep, 2015
Torres A, Newton SA, Crompton B, Borzutzky A, Neufeld EJ, Notarangelo L, Berry GT.   +6 more
europepmc   +1 more source

Targeting Nonsquamous Nonsmall Cell Lung Cancer via the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3-d]Pyrimidine Thienoyl Antifolates. [PDF]

Mol Pharmacol, 2016
Wilson MR, Hou Z, Yang S, Polin L, Kushner J, White K, Huang J, Ratnam M, Gangjee A, Matherly LH.   +9 more
europepmc   +1 more source

Prenatal Folinic Acid in FRAA-Positive Pregnancies: Preschool Neurodevelopmental Outcomes from a Pilot RCT Follow-Up. [PDF]

Nutrients
Giorlandino C, Mesoraca A, Margiotti K, Fabiani M, Cupellaro M, Giorlandino F, Mastrandrea ML, Raffio R, Pignataro F, Mangiafico L, D'Emidio L, Coco C, Milite V.   +12 more
europepmc   +1 more source