Results 11 to 20 of about 117,037 (362)

Association between proton pump inhibitor therapy and clostridium difficile infection: a contemporary systematic review and meta-analysis. [PDF]

, 2012
Introduction Emerging epidemiological evidence suggests that proton pump inhibitor (PPI) acid-suppression therapy is associated with an increased risk of Clostridium difficile infection (CDI).
A Deshpande, A Liberati, A Niklasson, Abdur Rahman Khan, Abed AlLehibi, Alex J. Sutton, Aref A. Bin Abdulhak, AZ Mat Saad, BT Batuwitage, C Bavishi, C Cahir, CM Wilcox, CS Eom, CS Kwok, D Ahrens, DF Stroup, DL Bhatt, DO Lowe, F Sierra, Faisal A. Alasmari, GH Guyatt, Imad M. Tleyjeh, J Johnstone, J Leonard, J Theisen, J Thorens, J Zhang, JL Peters, JM Boyce, JS Bajaj, KH Wilson, Larry M. Baddour, LC McDonald, LK Archibald, M Charlot, M Egger, Markus M. Heimesaat, MD Howell, MD Redelings, MM Nerandzic, Mohamad Al Tannir, Muhammad Riaz, Musa A. Garbati, Mushabab AlGhamdi, Patricia J. Erwin, PK Kutty, PS Yachimski, R DerSimonian, R Scagliarini, RL Jump, S Dial, S Janarthanan, S Jayatilaka, S Linney, S Schneeweiss, SG Moreno, SG Moreno, Talal Ibrahim, WR Jarvis   +58 more
core   +6 more sources

Association between proton pump inhibitor use and risk of fracture: A population-based case-control study.

PLoS ONE, 2020
ObjectivesThe purpose of this study was to reconfirm the association between the risk of fracture and proton pump inhibitor use and to establish evidence for defining a high-risk group of patients among proton pump inhibitor users.MethodsA nested case ...
Jong Joo Kim, Eun Jin Jang, Jiwon Park, Hyun Soon Sohn   +3 more
doaj   +1 more source

Proton pump inhibitors are associated with increased risk of development of chronic kidney disease [PDF]

, 2016
Background Acute interstitial nephritis secondary to proton pump inhibitors (PPIs) frequently goes undiagnosed due to its subacute clinical presentation, which may later present as chronic kidney disease (CKD).
Arora, Pradeep, Carter, Randolph L., Golzy, Mojgan, Gupta, Anu, Jalal, Kabir, Lohr, James W., Patel, Nilang   +6 more
core   +2 more sources

Proton Pump Inhibitors

World Chinese Journal of Digestology, 2013
Proton pump inhibitors (PPIs), omeprazole, lansoprazole, pantoprazole, rabeprazole, esomeprazole, and dexlansoprazole bind irreversibly to the H+, K+- ATPase (the “proton pump”) inhibiting its activity and decreasing gastric acid production.
Nghia H. Pham, Brian A. Baldo
openaire   +4 more sources

Iron deficiency anemia from iron malabsorption caused by proton pump inhibitors

eJHaem, 2020
Background Iron deficiency anemia without evidence for blood loss can present a diagnostic challenge. Proton pump inhibitors have been associated with iron deficiency anemia for many years, yet the relationship between the two until recently was not ...
Michael Boxer
doaj   +1 more source

Chronic cough and esomeprazole: A double-blind placebo-controlled parallel study [PDF]

, 2011
Background and objective: Gastro-oesophageal reflux has been implicated in the pathogenesis of chronic cough. Guidelines on management suggest a therapeutic trial of anti-reflux medication.
Beecher, Belafsky, Birring, Blondeau, Chang, Corley, Decalmer, DeVault, Dial, Eccles, Eherer, Everett, Faruqi, FitzGerald, Gilard, Gulmez, Hemmink, Herzig, Ing, Irwin, Irwin, Irwin, Irwin, Juurlink, Laheij, Lenglinger, Mastronarde, Morice, Morice, Morice, Morice, Noordzij, Pratter, Rostami-Hodjegan, Shaheen, Vaezi, Vertigan, Wager, Waring, Wo, Yang, Yearsley   +41 more
core   +1 more source

Prescribing trends of proton pump inhibitors, antipsychotics and benzodiazepines of medicare part d providers

BMC Geriatrics, 2022
Background Proton pump inhibitors, benzodiazepines, and antipsychotics are considered potentially inappropriate medications in older adults according to the American Geriatric Society Beers Criteria, and deprescribing algorithms have been developed to ...
Jennifer M. Toth, Saumil Jadhav, Holly M. Holmes, Manvi Sharma   +3 more
doaj   +1 more source

Knowledge-based best of breed approach for automated detection of clinical events based on German free text digital hospital discharge letters [PDF]

, 2019
OBJECTIVES: The secondary use of medical data contained in electronic medical records, such as hospital discharge letters, is a valuable resource for the improvement of clinical care (e.g. in terms of medication safety) or for research purposes. However,
Demuth, Ilja, Diekmann, Daniel, König, Maximilian, Sander, André, Steinhagen-Thiessen, Elisabeth   +4 more
core   +1 more source

Oral versus intravenous proton pump inhibitors in preventing re-bleeding for patients with peptic ulcer bleeding after successful endoscopic therapy

BMC Gastroenterology, 2012
Background High dose intravenous proton pump inhibitor after endoscopic therapy for peptic ulcer bleeding has been recommended as adjuvant therapy.
Yen Hsu-Heng, Yang Chia-Wei, Su Wei-Wen, Soon Maw-Soan, Wu Shun-Sheng, Lin Hwai-Jeng   +5 more
doaj   +1 more source

Structures and proton-pumping strategies of mitochondrial respiratory enzymes [PDF]

, 2001
Enzymes of the mitochondrial respiratory chain serve as proton pumps, using the energy made available from electron transfer reactions to transport protons across the inner mitochondrial membrane and create an electrochemical gradient used for the ...
Chan, Sunney I., Schultz, Brian E.
core   +1 more source