Results 21 to 30 of about 191,621 (404)

Concomitant Proton Pump Inhibitor Use and Survival in Urothelial Carcinoma Treated with Atezolizumab

open access: yesClinical Cancer Research, 2020
Purpose: Emerging evidence indicates that gut microbiota dysbiosis can reduce the effectiveness of immune checkpoint inhibitors (ICI). Proton pump inhibitors (PPI) are known to induce gut microbiota changes.
A. Hopkins   +4 more
semanticscholar   +1 more source

Association between proton pump inhibitor use and risk of fracture: A population-based case-control study.

open access: yesPLoS ONE, 2020
ObjectivesThe purpose of this study was to reconfirm the association between the risk of fracture and proton pump inhibitor use and to establish evidence for defining a high-risk group of patients among proton pump inhibitor users.MethodsA nested case ...
Jong Joo Kim   +3 more
doaj   +1 more source

Proton Pump Inhibitors and Clopidogrel [PDF]

open access: yesCardiovascular Therapeutics, 2010
Proton pump inhibitors are often prescribed for patients on clopidogrel to prevent gastrointestinal bleeding complications. Recent data suggest higher rates of adverse cardiovascular events in patients on proton pump inhibitors and clopidogrel, in comparison to patients on clopidogrel only.
Michael A, Gaglia, Ron, Waksman
openaire   +2 more sources

Clopidogrel and proton pump inhibitors [PDF]

open access: yesCanadian Medical Association Journal, 2014
In their comprehensive review of antithrombotic agents following acute coronary syndromes, Matteau and Bhatt[1][1] discuss the drug interaction between proton pump inhibitors and clopidogrel. They note that the COGENT trial, led by Bhatt, found no increased risk of major cardiovascular events at ...
openaire   +5 more sources

Comparison of Proton Pump Inhibitor and Triple Therapy Regimen for Laryngospharyngeal Reflux Disease

open access: yesJournal of Nepal Health Research Council, 2020
Background: Laryngopharyngeal reflux is retrograde flow of contents of the stomach to the larynx and the pharynx. The study aims to compare two regimens (proton pump inhibitor monotherapy versus triple therapy) on the outcome of Helicobactor pylori ...
Apar Pokharel   +2 more
doaj   +1 more source

Proton pump inhibitors are associated with increased risk of development of chronic kidney disease [PDF]

open access: yes, 2016
Background Acute interstitial nephritis secondary to proton pump inhibitors (PPIs) frequently goes undiagnosed due to its subacute clinical presentation, which may later present as chronic kidney disease (CKD).
Arora, Pradeep   +6 more
core   +2 more sources

Knowledge-based best of breed approach for automated detection of clinical events based on German free text digital hospital discharge letters [PDF]

open access: yes, 2019
OBJECTIVES: The secondary use of medical data contained in electronic medical records, such as hospital discharge letters, is a valuable resource for the improvement of clinical care (e.g. in terms of medication safety) or for research purposes. However,
Demuth, Ilja   +4 more
core   +1 more source

Iron deficiency anemia from iron malabsorption caused by proton pump inhibitors

open access: yeseJHaem, 2020
Background Iron deficiency anemia without evidence for blood loss can present a diagnostic challenge. Proton pump inhibitors have been associated with iron deficiency anemia for many years, yet the relationship between the two until recently was not ...
Michael Boxer
doaj   +1 more source

Proton Pump Inhibitors and CKD [PDF]

open access: yesJournal of the American Society of Nephrology, 2016
Proton pump inhibitors (PPIs) are taken by millions of people around the world, often for many months or even years, and some take PPIs on a permanent basis. PPIs, which are available both by prescription and over the counter, generally have an excellent overall safety profile.
Dennis G, Moledina, Mark A, Perazella
openaire   +2 more sources

Chronic cough and esomeprazole: A double-blind placebo-controlled parallel study [PDF]

open access: yes, 2011
Background and objective: Gastro-oesophageal reflux has been implicated in the pathogenesis of chronic cough. Guidelines on management suggest a therapeutic trial of anti-reflux medication.
Beecher   +41 more
core   +1 more source

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