Results 21 to 30 of about 139,988 (355)
Proton pump inhibitors (PPIs), omeprazole, lansoprazole, pantoprazole, rabeprazole, esomeprazole, and dexlansoprazole bind irreversibly to the H+, K+- ATPase (the “proton pump”) inhibiting its activity and decreasing gastric acid production.
Nghia H. Pham, Brian A. Baldo
openaire +4 more sources
Risk of Bacterial Infection from Proton Pump Inhibitor Use
Currently, proton pump inhibitors are used in a wide range of patients with gastroesophageal reflux disease, peptic ulcer, and upper gastrointestinal symptoms such as dyspepsia.
Sung Soo Kim +7 more
doaj +1 more source
Proton pump inhibitors affect the gut microbiome
Background and aims Proton pump inhibitors (PPIs) are among the top 10 most widely used drugs in the world. PPI use has been associated with an increased risk of enteric infections, most notably Clostridium difficile.
F. Imhann +16 more
semanticscholar +1 more source
OBJECTIVES:. Histamine-2 receptor antagonists are commonly administered for stress ulcer prophylaxis in critically ill adults and may be associated with delirium development.
Ami Shiddapur, BS +3 more
doaj +1 more source
Hypomagnesemia Induced by Long-Term Treatment with Proton-Pump Inhibitors
In 2006, hypomagnesemia was first described as a complication of proton-pump inhibitors. To address this issue, we systematically reviewed the literature.
Simone Janett +7 more
doaj +1 more source
BACKGROUND & AIMS Proton pump inhibitors (PPIs) are effective at treating acid-related disorders. These drugs are well tolerated in the short term, but long-term treatment was associated with adverse events in observational studies.
P. Moayyedi +49 more
semanticscholar +1 more source
ENDOSCOPIC AND HISTOPATHOLOGIC GASTRIC CHANGES IN CHRONIC USERS OF PROTON-PUMP INHIBITORS
Background Proton-pump inhibitors have been used for at least two decades. They are among the most commonly sold drugs in the world. However, some controversy remains about the indications for their use and the consequences of their prolonged use ...
Sílvia Maria Perrone CAMILO +5 more
doaj +1 more source
Proton Pump Inhibitors and Clopidogrel [PDF]
Proton pump inhibitors are often prescribed for patients on clopidogrel to prevent gastrointestinal bleeding complications. Recent data suggest higher rates of adverse cardiovascular events in patients on proton pump inhibitors and clopidogrel, in comparison to patients on clopidogrel only.
Ron Waksman, Michael A. Gaglia
openaire +2 more sources
Proton Pump Inhibitors and Gastritis
Proton pump inhibitors (PPIs) are novel compounds that strongly inhibit the H(+)/K(+)-ATPase in the gastric parietal cells to cause profound suppression of acid secretion. Acid-generating ATPase, also known as vacuolar-type ATPase, is located in the lysozomes of leukocytes and osteoclasts and its activity is also reportedly influenced by treatment with
Toshifumi Hibi +2 more
openaire +4 more sources
Proton pump inhibitors and dysbiosis: Current knowledge and aspects to be clarified
Proton pump inhibitors (PPIs) are common medications within the practice of gastroenterology. These drugs, which act through the irreversible inhibition of the hydrogen/potassium pump (H+/K+-ATPase pump) in the gastric parietal cells, are used in the ...
G. Bruno +7 more
semanticscholar +1 more source

