Regulation of RNA binding proteins in trypanosomatid protozoan parasites.
Posttranscriptional mechanisms have a critical role in the overall outcome of gene expression. These mechanisms are especially relevant in protozoa from the genus Trypanosoma, which is composed by death threatening parasites affecting people in Sub ...
M. Romaniuk +2 more
semanticscholar +4 more sources
Protein Lactylation Critically Regulates Energy Metabolism in the Protozoan Parasite Trypanosoma brucei [PDF]
Lysine lactylation has been recognized as a novel post-translational modification occurring on histones. However, lactylation in non-histone proteins, especially in proteins of early branching organisms, is not well understood.
Naiwen Zhang +7 more
semanticscholar +4 more sources
Identification of an uncharacterized protein as a novel regulator of Giardia lamblia virus (GLV) infection in Giardia duodenalis [PDF]
Giardia duodenalis (G. duodenalis) is a prevalent intestinal protozoan parasite responsible for causing diarrhea, particularly in children and travelers.
Zhiteng Zhao +10 more
doaj +2 more sources
Iron-inducible transcription of a malic enzyme gene (also reputed to be ap65-1) in Trichomonas vaginalis was previously shown to involve a Myb1 repressor and a Myb2 activator, each of which may preferentially select two closely spaced promoter sites, MRE-
Hong‐Ming Hsu +3 more
openalex +2 more sources
Posttranscriptional control and the role of RNA‐binding proteins in gene regulation in trypanosomatid protozoan parasites [PDF]
Sandra M. Fernández‐Moya +1 more
openalex +2 more sources
Glycosylated proteins in the protozoan algaEuglena gracilis: a proteomic approach [PDF]
AbstractProtein glycosylation, and in particular N-linked glycans, is a hallmark of eukaryotic cells and has been well-studied in mammalian cells and parasites. However, little research has been conducted to investigate the conservation and variation of protein glycosylation pathways in other eukaryotic organisms.
Ellis C. O’Neill
openalex +3 more sources
Characterization of unusual families of ATG8-like proteins and ATG12 in the protozoan parasiteLeishmania major [PDF]
Roderick Williams +4 more
openalex +2 more sources
Protein acetylation in the critical biological processes in protozoan parasites [PDF]
Protein lysine acetylation has emerged as a major regulatory post-translational modification in different organisms, present not only on histone proteins affecting chromatin structure and gene expression but also on nonhistone proteins involved in several cellular processes. The same scenario was observed in protozoan parasites after the description of
Suellen Rodrigues Maran +8 more
openalex +7 more sources
Production of recombinant proteins from protozoan parasites. [PDF]
Although the past decade has witnessed sequencing from an increasing number of parasites, modern high-throughput DNA sequencing technologies have the potential to generate complete genome sequences at even higher rates. Along with the discovery of genes that might constitute potential targets for chemotherapy or vaccination, the need for novel protein ...
J. Fernández-Robledo, G. Vasta
semanticscholar +3 more sources
ProtVirDB: a database of protozoan virulent proteins [PDF]
Abstract Summary: ProtVirDB is a comprehensive and user-friendly web-based knowledgebase of virulent proteins belonging to protozoan species. The database will facilitate research and provide an integrated platform for comparative studies of virulent proteins in different parasitic protozoans and organize them under a unifying ...
Jayashree Ramana, D. Gupta
semanticscholar +4 more sources

