Entamoeba histolytica is responsible for amoebiasis in humans. Its atypical cell cycle events and unique stress defense mechanisms make it different from other protozoan parasites.
Pinaki Biswas +4 more
doaj +1 more source
Identification of putative potassium channel homologues in pathogenic protozoa. [PDF]
K(+) channels play a vital homeostatic role in cells and abnormal activity of these channels can dramatically alter cell function and survival, suggesting that they might be attractive drug targets in pathogenic organisms.
David L Prole, Neil V Marrion
doaj +1 more source
Heat shock protein 90 from neglected protozoan parasites
Significant advances have been made in our understanding of heat shock protein 90 (Hsp90) in terms of its structure, biochemical characteristics, post-translational modifications, interactomes, regulation and functions. In addition to yeast as a model several new systems have now been examined including flies, worms, plants as well as mammalian cells ...
Roy, Nainita +3 more
openaire +3 more sources
An ancestral secretory apparatus in the protozoan parasite Giardia intestinalis [PDF]
The protozoan parasite Giardia intestinalis belongs to one of the earliest diverged eukaryotic lineages. This is also reflected in a simple intracellular organization, as Giardia lacks common subcellular compartments such as mitochondria, peroxisomes ...
Hehl, Adrian B. +7 more
core +1 more source
Protein Lactylation Critically Regulates Energy Metabolism in the Protozoan Parasite Trypanosoma brucei [PDF]
Lysine lactylation has been recognized as a novel post-translational modification occurring on histones. However, lactylation in non-histone proteins, especially in proteins of early branching organisms, is not well understood. Energy metabolism and the histone repertoire in the early diverging protozoan parasite Trypanosoma brucei, the causative agent
Naiwen Zhang +15 more
openaire +3 more sources
Proteomic Identification of Oxidized Proteins in Entamoeba histolytica by Resin-Assisted Capture: Insights into the Role of Arginase in Resistance to Oxidative Stress. [PDF]
Entamoeba histolytica is an obligate protozoan parasite of humans, and amebiasis, an infectious disease which targets the intestine and/or liver, is the second most common cause of human death due to a protozoan after malaria.
Preeti Shahi +7 more
doaj +1 more source
Release of Ecto-protein Kinases by the Protozoan ParasiteLeishmania major [PDF]
Leishmania major promastigotes have externally oriented ecto-protein kinases (PK) that are capable of phosphorylating both endogenous membrane substrates and foreign proteins. Live parasites phosphorylate protamine sulfate, casein, and phosvitin but not bovine serum albumin.
N, Sacerdoti-Sierra, C L, Jaffe
openaire +2 more sources
Evolution of apoptosis-like programmed cell death in unicellular protozoan parasites
Apoptosis-like programmed cell death (PCD) has recently been described in multiple taxa of unicellular protists, including the protozoan parasites Plasmodium, Trypanosoma and Leishmania.
Reece Sarah E +2 more
doaj +1 more source
Tracking autophagy during proliferation and differentiation of trypanosoma brucei [PDF]
Autophagy is a lysosome-dependent degradation mechanism that sequesters target cargo into autophagosomal vesicles. The Trypanosoma brucei genome contains apparent orthologues of several autophagy-related proteins including an ATG8 family. These ubiquitin-
Coombs, Graham H. +3 more
core +3 more sources
Proteomic analysis of the ventral disc of
Background Giardia lamblia is a multiflagellated protozoan that inhabits the small intestine of vertebrates, causing giardiasis. To colonize the small intestine, the trophozoites form of the parasite remains attached to intestinal epithelial cells by ...
Lourenço Daniela +5 more
doaj +1 more source

