Results 41 to 50 of about 71,120 (247)

Molecular characterization of EhAK6, an endonuclease V domain-containing aurora kinase protein from Entamoeba histolytica: Protein-protein interaction, docking and functional aspect

open access: yesCurrent Research in Biotechnology, 2021
Entamoeba histolytica is responsible for amoebiasis in humans. Its atypical cell cycle events and unique stress defense mechanisms make it different from other protozoan parasites.
Pinaki Biswas   +4 more
doaj   +1 more source

Identification of putative potassium channel homologues in pathogenic protozoa. [PDF]

open access: yesPLoS ONE, 2012
K(+) channels play a vital homeostatic role in cells and abnormal activity of these channels can dramatically alter cell function and survival, suggesting that they might be attractive drug targets in pathogenic organisms.
David L Prole, Neil V Marrion
doaj   +1 more source

Heat shock protein 90 from neglected protozoan parasites

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2012
Significant advances have been made in our understanding of heat shock protein 90 (Hsp90) in terms of its structure, biochemical characteristics, post-translational modifications, interactomes, regulation and functions. In addition to yeast as a model several new systems have now been examined including flies, worms, plants as well as mammalian cells ...
Roy, Nainita   +3 more
openaire   +3 more sources

An ancestral secretory apparatus in the protozoan parasite Giardia intestinalis [PDF]

open access: yes, 2003
The protozoan parasite Giardia intestinalis belongs to one of the earliest diverged eukaryotic lineages. This is also reflected in a simple intracellular organization, as Giardia lacks common subcellular compartments such as mitochondria, peroxisomes ...
Hehl, Adrian B.   +7 more
core   +1 more source

Protein Lactylation Critically Regulates Energy Metabolism in the Protozoan Parasite Trypanosoma brucei [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2021
Lysine lactylation has been recognized as a novel post-translational modification occurring on histones. However, lactylation in non-histone proteins, especially in proteins of early branching organisms, is not well understood. Energy metabolism and the histone repertoire in the early diverging protozoan parasite Trypanosoma brucei, the causative agent
Naiwen Zhang   +15 more
openaire   +3 more sources

Proteomic Identification of Oxidized Proteins in Entamoeba histolytica by Resin-Assisted Capture: Insights into the Role of Arginase in Resistance to Oxidative Stress. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2016
Entamoeba histolytica is an obligate protozoan parasite of humans, and amebiasis, an infectious disease which targets the intestine and/or liver, is the second most common cause of human death due to a protozoan after malaria.
Preeti Shahi   +7 more
doaj   +1 more source

Release of Ecto-protein Kinases by the Protozoan ParasiteLeishmania major [PDF]

open access: yesJournal of Biological Chemistry, 1997
Leishmania major promastigotes have externally oriented ecto-protein kinases (PK) that are capable of phosphorylating both endogenous membrane substrates and foreign proteins. Live parasites phosphorylate protamine sulfate, casein, and phosvitin but not bovine serum albumin.
N, Sacerdoti-Sierra, C L, Jaffe
openaire   +2 more sources

Evolution of apoptosis-like programmed cell death in unicellular protozoan parasites

open access: yesParasites & Vectors, 2011
Apoptosis-like programmed cell death (PCD) has recently been described in multiple taxa of unicellular protists, including the protozoan parasites Plasmodium, Trypanosoma and Leishmania.
Reece Sarah E   +2 more
doaj   +1 more source

Tracking autophagy during proliferation and differentiation of trypanosoma brucei [PDF]

open access: yes, 2014
Autophagy is a lysosome-dependent degradation mechanism that sequesters target cargo into autophagosomal vesicles. The Trypanosoma brucei genome contains apparent orthologues of several autophagy-related proteins including an ATG8 family. These ubiquitin-
Coombs, Graham H.   +3 more
core   +3 more sources

Proteomic analysis of the ventral disc of Giardia lamblia

open access: yesBMC Research Notes, 2012
Background Giardia lamblia is a multiflagellated protozoan that inhabits the small intestine of vertebrates, causing giardiasis. To colonize the small intestine, the trophozoites form of the parasite remains attached to intestinal epithelial cells by ...
Lourenço Daniela   +5 more
doaj   +1 more source

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