Results 21 to 30 of about 42,476 (197)

Release of Ecto-protein Kinases by the Protozoan ParasiteLeishmania major [PDF]

open access: yesJournal of Biological Chemistry, 1997
Leishmania major promastigotes have externally oriented ecto-protein kinases (PK) that are capable of phosphorylating both endogenous membrane substrates and foreign proteins. Live parasites phosphorylate protamine sulfate, casein, and phosvitin but not bovine serum albumin.
N, Sacerdoti-Sierra, C L, Jaffe
openaire   +2 more sources

Human, vector and parasite Hsp90 proteins: A comparative bioinformatics analysis

open access: yesFEBS Open Bio, 2015
The treatment of protozoan parasitic diseases is challenging, and thus identification and analysis of new drug targets is important. Parasites survive within host organisms, and some need intermediate hosts to complete their life cycle.
Ngonidzashe Faya   +2 more
doaj   +1 more source

Identification of putative potassium channel homologues in pathogenic protozoa. [PDF]

open access: yesPLoS ONE, 2012
K(+) channels play a vital homeostatic role in cells and abnormal activity of these channels can dramatically alter cell function and survival, suggesting that they might be attractive drug targets in pathogenic organisms.
David L Prole, Neil V Marrion
doaj   +1 more source

Molecular characterization of EhAK6, an endonuclease V domain-containing aurora kinase protein from Entamoeba histolytica: Protein-protein interaction, docking and functional aspect

open access: yesCurrent Research in Biotechnology, 2021
Entamoeba histolytica is responsible for amoebiasis in humans. Its atypical cell cycle events and unique stress defense mechanisms make it different from other protozoan parasites.
Pinaki Biswas   +4 more
doaj   +1 more source

Proteomic Identification of Oxidized Proteins in Entamoeba histolytica by Resin-Assisted Capture: Insights into the Role of Arginase in Resistance to Oxidative Stress. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2016
Entamoeba histolytica is an obligate protozoan parasite of humans, and amebiasis, an infectious disease which targets the intestine and/or liver, is the second most common cause of human death due to a protozoan after malaria.
Preeti Shahi   +7 more
doaj   +1 more source

Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins

open access: yesNature Communications, 2019
Giardia lamblia express a dense coat of variant-specific surface proteins (VSPs) on trophozoites that protects the parasite inside the host´s intestine. Here the authors show that stability and immunomodulatory properties of VSPs can be exploited to both
Marianela C. Serradell   +18 more
doaj   +1 more source

Evolution of apoptosis-like programmed cell death in unicellular protozoan parasites

open access: yesParasites & Vectors, 2011
Apoptosis-like programmed cell death (PCD) has recently been described in multiple taxa of unicellular protists, including the protozoan parasites Plasmodium, Trypanosoma and Leishmania.
Reece Sarah E   +2 more
doaj   +1 more source

Proteomic analysis of the ventral disc of Giardia lamblia

open access: yesBMC Research Notes, 2012
Background Giardia lamblia is a multiflagellated protozoan that inhabits the small intestine of vertebrates, causing giardiasis. To colonize the small intestine, the trophozoites form of the parasite remains attached to intestinal epithelial cells by ...
Lourenço Daniela   +5 more
doaj   +1 more source

Proteins of the Ciliated Protozoan Parasite Ichthyophthirius multifiliis Identified in Common Carp Skin Mucus

open access: yesPathogens, 2021
The skin mucus is the fish primary defense barrier protecting from infections via the skin epidermis. In a previous study, we have investigated the proteome of common carp (Cyprinus carpio) skin mucus at two different time points (1 and 9 days) post ...
Mona Saleh   +4 more
doaj   +1 more source

Regulation of RNA binding proteins in trypanosomatid protozoan parasites

open access: yesWorld Journal of Biological Chemistry, 2016
Posttranscriptional mechanisms have a critical role in the overall outcome of gene expression. These mechanisms are especially relevant in protozoa from the genus Trypanosoma, which is composed by death threatening parasites affecting people in Sub-saharan Africa or in the Americas.
Romaniuk, María Albertina   +2 more
openaire   +3 more sources

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