Results 11 to 20 of about 42,476 (197)
Protein acetylation in the critical biological processes in protozoan parasites [PDF]
Protein lysine acetylation has emerged as a major regulatory post-translational modification in different organisms, present not only on histone proteins affecting chromatin structure and gene expression but also on nonhistone proteins involved in several cellular processes. The same scenario was observed in protozoan parasites after the description of
Suellen Rodrigues Maran +8 more
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ProtVirDB: a database of protozoan virulent proteins [PDF]
Abstract Summary: ProtVirDB is a comprehensive and user-friendly web-based knowledgebase of virulent proteins belonging to protozoan species. The database will facilitate research and provide an integrated platform for comparative studies of virulent proteins in different parasitic protozoans and organize them under a unifying ...
Dinesh Gupta, Jayashree Ramana
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Released Parasite-Derived Kinases as Novel Targets for Antiparasitic Therapies
The efficient manipulation of their host cell is an essential feature of intracellular parasites. Most molecular mechanisms governing the subversion of host cell by protozoan parasites involve the release of parasite-derived molecules into the host cell ...
Anne Silvestre +3 more
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Genomic Databases and the Search of Protein Targets for Protozoan Parasites [PDF]
The development of databases devoted to biological information opened the possibility to integrate, query and analyze biological data obtained from several sources that otherwise would be scattered through the web. Several issues arise in the handling of biological information, mainly due to the diversity of biological subject matter and the complexity
Luís Fernando S M, Timmers +6 more
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Protein arginine methyltransferases in protozoan parasites
AbstractArginine methylation is a post-translational modification involved in gene transcription, signalling pathways, DNA repair, RNA metabolism and splicing, among others, mechanisms that in protozoa parasites may be involved in pathogenicity-related events.
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Duffy blood group system and the malaria adaptation process in humans
Malaria is an acute infectious disease caused by the protozoa of the genus Plasmodium. The antigens of the Duffy Blood Group System, in addition to incompatibilities in transfusions and hemolytic disease of the newborn, are of great interest in medicine ...
Gledson Barbosa de Carvalho +1 more
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Identification and Characterization of a Protozoan Uncoupling Protein in Acanthamoeba castellanii [PDF]
An uncoupling protein (UCP) has been identified in mitochondria from Acanthamoeba castellanii, a nonphotosynthetic soil amoeboid protozoon that, in molecular phylogenesis, appears on a branch basal to the divergence points of plants, animals, and fungi. The existence of UCP in A.
Jarmuszkiewicz, Wieslawa +3 more
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Advances in understanding red blood cell modifications by Babesia
Babesia are tick-borne protozoan parasites that can infect livestock, pets, wildlife animals, and humans. In the mammalian host, they invade and multiply within red blood cells (RBCs).
Hassan Hakimi +3 more
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Protein palmitoylation in protozoan parasites
Palmitoylation plays an important role in the regulation of the localization and function of the modified protein. Although many aspects of protein palmitoylation have been identified in mammalian and yeast cells, little information is available of this modification in protozoan parasites.
Maria Martha, Corvi +2 more
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The NF-κB Pathway: Modulation by Entamoeba histolytica and Other Protozoan Parasites
Protozoan parasites have led to worldwide devastation because of their ability to cause infectious diseases. They have evolved as successful pathogens in part because of their remarkable and sophisticated ways to evade innate host defenses.
Attinder Chadha, Kris Chadee
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