Molecular cold‐adaptation: Comparative analysis of two homologous families of psychrophilic and mesophilic signal proteins of the protozoan ciliate, Euplotes [PDF]
IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology, 2009 Claudio Alimenti +4 more
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Release of Ecto-protein Kinases by the Protozoan ParasiteLeishmania major [PDF]
Journal of Biological Chemistry, 1997 Leishmania major promastigotes have externally oriented ecto-protein kinases (PK) that are capable of phosphorylating both endogenous membrane substrates and foreign proteins. Live parasites phosphorylate protamine sulfate, casein, and phosvitin but not bovine serum albumin.
Nina Sacerdoti‐Sierra +1 more
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Zoonotic Malaria Risk in Serra Do Mar, Atlantic Forest, Brazil
Microorganisms, 2023 Here, the main goal is to assess natural infections of Plasmodium spp. in anophelines in a forest reserve from the same region where we previously found a surprisingly high rate (5.2%) of plasmodia infections (n = 25) in Kerteszia mosquitoes (N = 480) on
Marina E. O. Rangel +7 more
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The Defensive Interactions of Prominent Infectious Protozoan Parasites: The Host’s Complement System
Biomolecules, 2022 The complement system exerts crucial functions both in innate immune responses and adaptive humoral immunity. This pivotal system plays a major role dealing with pathogen invasions including protozoan parasites.
Sajad Rashidi +5 more
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Selenium and protozoan parasitic infections: selenocompounds and selenoproteins potential
Parasitology Research, 2022 The current drug treatments against protozoan parasitic diseases including Chagas, malaria, leishmaniasis, and toxoplasmosis represent good examples of drug resistance mechanisms and have shown diverse side effects. Therefore, the identification of novel
S. Rashidi +7 more
semanticscholar +1 more source
Frontiers in Genetics, 2022 Small GTPases are the key to actin cytoskeleton signaling, which opens the lock of effector proteins to forward the signal downstream in several cellular pathways. Actin cytoskeleton assembly is associated with cell polarity, adhesion, movement and other
Preeti Umarao +2 more
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A target repurposing approach identifies N-myristoyltransferase as a new candidate drug target in filarial nematodes. [PDF]
PLoS Neglected Tropical Diseases, 2014 Myristoylation is a lipid modification involving the addition of a 14-carbon unsaturated fatty acid, myristic acid, to the N-terminal glycine of a subset of proteins, a modification that promotes their binding to cell membranes for varied biological ...
Brendan D Galvin +7 more
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N-linked glycosylation of proteins in the protozoan parasite Toxoplasma gondii [PDF]
Molecular and Biochemical Parasitology, 2020 Toxoplasma gondii is an obligate intracellular parasite of animal cells. Infection of humans is common and may result in devastating disease, especially in immunocompromised individuals. Despite previous reports that N-glycosylation of proteins may be a rare post-translational modification in this and related organisms, we demonstrate that it is ...
Flora C. Y. Luk +2 more
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Role of Host Small GTPases in Apicomplexan Parasite Infection
Microorganisms, 2022 The Apicomplexa are obligate intracellular parasites responsible for several important human diseases. These protozoan organisms have evolved several strategies to modify the host cell environment to create a favorable niche for their survival.
Silvio Paone, Anna Olivieri
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Released Parasite-Derived Kinases as Novel Targets for Antiparasitic Therapies
Frontiers in Cellular and Infection Microbiology, 2022 The efficient manipulation of their host cell is an essential feature of intracellular parasites. Most molecular mechanisms governing the subversion of host cell by protozoan parasites involve the release of parasite-derived molecules into the host cell ...
Anne Silvestre +3 more
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