Results 71 to 80 of about 93 (92)
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Protein and RNA inhibitors and protozoan habituation
Psychopharmacologia, 1970A variety of protein and RNA inhibitors were tested on habituation learning in the protozoan Spirostomum. Inhibition of protein synthesis up to values of 95% had no effect upon habituation, and RNA inhibition up to 89% by 5-fluorouracil had only slight effects upon it. Large amounts of protein and RNA synthesis are not necessary for habituation.
Philip B. Applewhite, Frank T. Gardner
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Isoprenylation of proteins in the protozoan Giardia lamblia
Molecular and Biochemical Parasitology, 1995We report the ability of Giardia lamblia to modify several of its cellular proteins by isoprenylation. Trophozoites cultured in the presence of [3H]mevalonate synthesized radiolabeled proteins of approx. 50 and 21-26 kDa. Chemical analysis indicated that farnesyl and geranylgeranyl isoprenoids comprised the majority of the radiolabel covalently ...
Michael R. Mowatt +3 more
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Glycosylation of proteins in the protozoan Euglena gracilis
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1985Abstract 1. 1. The main dolichol-P-P-bound oligosaccharide present in Euglena gracilis cells incubated with [U- 14 C]glucose was found to migrate on paper chromatography as a Glc 3 Man 9 GlcNAc 2 standard and to contain glucose, mannose and N- acetylglucosamine residues. 2. 2.
Laura de la Canal, Armando J. Parodi
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Using Protozoan Surface Proteins for Effective Oral Vaccination
Trends in Parasitology, 2020The Global Vaccine Action Plan of the World Health Organization (WHO) calls for nonsyringe delivery mechanisms, thermostable vaccines, and new bioprocessing technologies as priority research areas. Here we discuss the use of protozoan surface proteins to develop a safe, stable, and efficient versatile oral vaccine platform.
Hugo D. Lujan +3 more
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Pathogenic role of mitogen activated protein kinases in protozoan parasites
Biochimie, 2022Protozoan parasites with complex life cycles have high mortality rates affecting billions of human lives. Available anti-parasitic drugs are inadequate due to variable efficacy, toxicity, poor patient compliance and drug-resistance. Hence, there is an urgent need for the development of safer and better chemotherapeutics.
Pavneet Kaur, Neena Goyal
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Dna-Protein Interactions at Telomeres in Ciliated Protozoans
Advances in Molecular and Cell Biology, 1988Publisher Summary This chapter discusses the DNA–protein complexes found at telomeres in the macronuclei of ciliated protozoans, with special attention given to studies in Oxytricha (a hypotrichous ciliate) and Tetrahymena (a holotrichous ciliate). The structure of telomeres has been largely elucidated by studies on macronuclear DNA from ciliated
Virginia A. Zakian +1 more
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Protein synthesis and cell division in a pyrimidine-starved protozoan
Experimental Cell Research, 1960Abstract In media complete save for uracil, T. pyriformis continues to make protein, divide, and form normal cells, although its net RNA content does not increase. Uracil-starved cells rapidly regain their original RNA level when uracil is restored.
S. Lederberg, Daniel Mazia
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The Cell Type-Specific Signal Proteins (Pheromones) of Protozoan Ciliates
Current Pharmaceutical Design, 2006In association with their mechanisms of self/non-self recognition (known as mating type systems), ciliates synthesize and constitutively secrete cell type-specific proteins into their extracellular medium. These proteins, designated as pheromones, have been isolated from species of Euplotes and shown to be members of families of structurally homologous
P. LUPORINI +3 more
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Pore-forming proteins in pathogenic protozoan parasites
Trends in Microbiology, 1997Pore-forming proteins (PFPs) may play important roles in pathogenesis by protozoan parasites by either directly damaging the plasma membrane of the host cells or ensuring intracellular survival of the parasites by promoting their exit from lysosomal vacuoles.
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Characterization of Trichomonas vaginalis virus proteins in the pathogenic protozoan T. vaginalis
Archives of Virology, 1998The 4.6-kb double-stranded (ds) RNA of Trichomonas vaginalis virus (TVV)-T1 has been shown to encode two overlapping genes, cap and pol. In this study, a serum for specifically detecting viral cap gene product was raised against a recombinant protein, and sera for specifically detecting pol gene product were raised against synthetic oligopeptides. A 75-
Y. D. Chu +2 more
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