A longitudinal study of children identifies antibody Fc-mediated functions and antigen targets of immunity to Plasmodium vivax malaria. [PDF]
Opi DH +16 more
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Relationship between antibody avidity, Fc-mediated functional activity and longevity of malaria vaccine responses in clinical trials. [PDF]
Horton JL +11 more
europepmc +1 more source
Helminth-induced immune modulation in colorectal cancer: exploring therapeutic applications. [PDF]
Li H +12 more
europepmc +1 more source
TEpiNom: A computational framework integrating population data to prioritize Plasmodium falciparum T cell epitopes. [PDF]
Laurenson AJ +3 more
europepmc +1 more source
The control of diseases caused by protozoan parasites is one of the United Nations' Sustainable Development Goals. In recent years much research effort has gone into developing a new generation of live attenuated vaccines (LAVs) against malaria, Chagas disease and leishmaniasis. However, there is a bottleneck related to their biosafety, production, and
Jose Carlos Solana +2 more
exaly +4 more sources
DNA Vaccines against Protozoan Parasites: Advances and Challenges [PDF]
Over the past 15 years, DNA vaccines have gone from a scientific curiosity to one of the most dynamic research field and may offer new alternatives for the control of parasitic diseases such as leishmaniasis and Chagas disease. We review here some of the advances and challenges for the development of DNA vaccines against these diseases.
Eric Dumonteil
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Developing vaccines to control protozoan parasites in ruminants: Dead or alive?
Protozoan parasites are among some of the most successful organisms worldwide, being able to live and multiply within a very wide range of hosts. The diseases caused by these parasites cause significant production losses in the livestock sector involving reproductive failure, impaired weight gain, contaminated meat, reduced milk yields and in severe ...
Alison Burrells +2 more
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Using Protozoan Surface Proteins for Effective Oral Vaccination
Trends in Parasitology, 2020The Global Vaccine Action Plan of the World Health Organization (WHO) calls for nonsyringe delivery mechanisms, thermostable vaccines, and new bioprocessing technologies as priority research areas. Here we discuss the use of protozoan surface proteins to develop a safe, stable, and efficient versatile oral vaccine platform.
Lucia Lara Rupil
exaly +3 more sources
Systems vaccinology for the design of rational vaccines against protozoan parasites
2022Anabel Elisa Rodriguez
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