Results 141 to 150 of about 11,003 (167)
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Antiparasitic protozoan vaccines
Expert Opinion on Therapeutic Patents, 2001Parasitic infections caused by pathogenic protozoa affect over 1 billion people worldwide and impose a substantial health and economic burden, particularly on inter-tropical less-developed countries where they are more prevalent. Despite encouraging progress in vaccine development, chemotherapy remains the single most effective, efficient and ...
Carmen Ochoa, Antonio R Martinez
exaly +2 more sources
Molecular Pharmaceutics, 2020
DNA vaccinations are promising strategies for treating diseases that require cellular immunity (i.e., cancer and protozoan infection). Here, we report on the use of a liposomal nanocarrier (lipid nanoparticles (LNPs)) composed of an SS-cleavable and pH-activated lipidlike material (ssPalm) as an in vivo DNA vaccine.
Hiroki Tanaka +2 more
exaly +3 more sources
DNA vaccinations are promising strategies for treating diseases that require cellular immunity (i.e., cancer and protozoan infection). Here, we report on the use of a liposomal nanocarrier (lipid nanoparticles (LNPs)) composed of an SS-cleavable and pH-activated lipidlike material (ssPalm) as an in vivo DNA vaccine.
Hiroki Tanaka +2 more
exaly +3 more sources
Virus-Like Particle Vaccines Against Respiratory Viruses and Protozoan Parasites
2021The field of vaccinology underwent massive advances over the past decades with the introduction of virus-like particles (VLPs), a supra-molecular nanoparticle vaccine platform that resembles viral structures without the ability to replicate in hosts. This innovative approach has been remarkably effective, as evidenced by its profound immunogenicity and
Ki-Back, Chu, Fu-Shi, Quan
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A Comprehensive Review of Tick-Born Blood Protozoan Disease in Cattle: Babesiosis and Vaccination
International Journal of Medical Parasitology and Epidemiology Sciences, 2023Babesiosis is a tick-borne blood protozoan cattle disease caused by the genus Babesia worldwide and in tropical and subtropical regions. It is mainly caused by Babesia bovis and Babesia bigemina in cattle. When merozoites enter the erythrocyte, the surface coat of B. bigemina produces many merozoite surface antigens.
Zia ul Rehman Khalid +4 more
openaire +1 more source
Trends and Advances in Vaccines Against Protozoan Parasites of Veterinary Importance: A Review
Journal of Biological Sciences, 2014 A.K. Singh +6 more
exaly +2 more sources
Cryopreservation of an Attenuated Vaccine Strain of the Protozoan ParasiteToxoplasma gondii
Cryobiology, 1996Toxoplasma gondii is a protozoan parasite that infects birds and mammals, including humans. T. gondii T-263 is an attenuated mutant strain that is being developed as a live vaccine to protect cats from shedding oocysts. A cryopreservation procedure for T. gondii T-263 bradyzoites has been developed to meet the requirement for product stability. A Me2SO-
K S, Booth, E R, James, I, Popiel
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2021
Giardia lamblia is the only known parasite that can inhabit the harsh upper gastrointestinal tract, where most of the digestive proteases are secreted. Intestinal and free-living protozoa express surface proteins containing an extraordinarily high percentage of cysteine.
Rupil, Lucía Lara dir. +2 more
openaire +2 more sources
Giardia lamblia is the only known parasite that can inhabit the harsh upper gastrointestinal tract, where most of the digestive proteases are secreted. Intestinal and free-living protozoa express surface proteins containing an extraordinarily high percentage of cysteine.
Rupil, Lucía Lara dir. +2 more
openaire +2 more sources
Use of Hybridoma Antibodies and Recombinant DNA Technology in Protozoan Vaccine Development
Avian Diseases, 1986The use of hybridoma antibodies developed against the sporozoite stage of avian coccidia, coupled with genetic-engineering techniques, has made it possible to begin bird-immunization studies utilizing an Escherichia coli-elicited coccidial protein. The coccidia are currently controlled in the poultry industry by use of anticoccidial compounds, but it ...
H D, Danforth, P C, Augustine
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Aquaculture, 1993
Abstract Goldfish ( Carassius auratus ) were vaccinated with live tomites of Ichthyophthirius multifiliis (Fouquet) and Tetrahymena pyriformis (Lwoff) by immersion or intraperitoneal injection. They were then challenged with I. multifiliis and some other common ectoparasitic protozoans, such as Oodinium pillularis (Schaperclaus), Ichthyobodo
Ling, K.H., Sin, Y.M., Lam, T.J.
openaire +1 more source
Abstract Goldfish ( Carassius auratus ) were vaccinated with live tomites of Ichthyophthirius multifiliis (Fouquet) and Tetrahymena pyriformis (Lwoff) by immersion or intraperitoneal injection. They were then challenged with I. multifiliis and some other common ectoparasitic protozoans, such as Oodinium pillularis (Schaperclaus), Ichthyobodo
Ling, K.H., Sin, Y.M., Lam, T.J.
openaire +1 more source
Current Medicinal Chemistry
Background: Neglected parasitic diseases constitute a broad spectrum of clinical conditions that, in the chronic phase, lack effective therapies for the target population. The utilization of vaccines based on liposomal nanocarrier systems is emerging, thereby enhancing clinical outcomes in various comorbidities. Consequently, this study aims to assess
Francisco Dantas, Lourenço +8 more
openaire +2 more sources
Background: Neglected parasitic diseases constitute a broad spectrum of clinical conditions that, in the chronic phase, lack effective therapies for the target population. The utilization of vaccines based on liposomal nanocarrier systems is emerging, thereby enhancing clinical outcomes in various comorbidities. Consequently, this study aims to assess
Francisco Dantas, Lourenço +8 more
openaire +2 more sources