Results 91 to 100 of about 16,784 (210)
Microbial metabolites in tumor epigenetic regulation
iMeta, Volume 5, Issue 1, February 2026.The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang +31 more
wiley +1 more source
Journal of Medical Virology, Volume 98, Issue 2, February 2026.ABSTRACT HTLV‐1 infection is a chronic condition associated with the development of malignancies, inflammatory, and neurological disorders. In this study, the causes of hospitalization and mortality were assessed in a cohort of 508 individuals living with HTLV‐1 followed over a 30‐year period. Overall mortality was 8.5% in this population and increased
Elizabeth Souza Neves +10 more
wiley +1 more source
Frontiers in Cellular and Infection MicrobiologyIntroductionAlterations in the immune response may influence the development of HTLV-1-associated diseases. TLR3 detects viral nucleic acids, including HTLV-1, and triggers the production of IFN-I and other cytokines. Genetic variations in TLR3 may alter
Fabiane dos Santos Ferreira +18 more
doaj +1 more source
Chronic adult T-cell Leukemia in a young male after blood transfusion as a newborn [PDF]
, 2016 Human T-cell Lymphotropic virus type 1 (HTLV-1) is the etiological agent of Adult T-cell Leukemia/Lymphoma (ATLL) and HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis (HTM/TSP).
Altube, Alejandra +10 more
core +2 more sources
American Journal of Veterinary Research, 2007 Abstract Objective—To determine proviral load in bovine leukemia virus (BLV)–infected cattle with and without persistent lymphocytosis to assess the potential of transmitting the virus. Animals—Cattle in 6 dairy herds. Procedures—Blood samples from infected cows were evaluated 3 times at 6-month intervals for determination of proviral load via PCR ...
Juliarena, Marcela Alicia +2 more
openaire +3 more sources
Protease‐mediated maturation of M‐PMV reverse transcriptase into a functional heterodimer
Protein Science, Volume 35, Issue 2, February 2026.Abstract Reverse transcriptase (RT) of retroviruses orchestrates viral replication, yet its structural diversity remains poorly understood. Well‐studied RTs, such as those from HIV‐1, murine leukemia virus, and avian myeloblastosis virus, were characterized decades ago, but less prominent retroviruses have escaped detailed analysis.
Marina Kapisheva +6 more
wiley +1 more source
MicroRNA-29 family expression and its relation to antiviral immune response and viro-immunological markers in HIV-1-infected patients [PDF]
, 2015 BACKGROUND: Several in vitro studies suggested the microRNA-29 (miRNA-29) family is involved in regulating HIV-1 and modulating the expression of interleukin (IL)-32, an anti-HIV-1 cytokine.
ANTONELLI, Guido +9 more
core +2 more sources
Smart Medicine, Volume 5, Issue 1, February 2026.We provide the first comprehensive analysis of changes in the gut bacteriome at different clinical stages of HTLV‐1 infection. HTLV‐1 infection is associated with a dysbiosis that includes reduced bacterial diversity and an inverted Firmicutes/Bacteroidetes ratio.
Lorena Abreu Fernandes +8 more
wiley +1 more source
Sexual transmission of human T-cell lymphotropic virus type 1 [PDF]
, 2014 Human T-cell lymphotropic virus type 1 (HTLV-1) is endemic in many parts of the world and is primarily transmitted through sexual intercourse or from mother to child.
Casseb, Jorge Simão do Rosário +1 more
core +1 more source
Recent Developments in HIV Antivirals: The Prospect of Prophylactic Drugs to Change the Pandemic
Microbial Biotechnology, Volume 19, Issue 2, February 2026.Replication cycle of HIV‐1. The scheme provides an overview from virus entry over reverse transcription of viral RNA into viral DNA, provirus DNA integration into the host genome, genome expression by transcription and translation, proteolytic processing of the viral polyproteins, viral maturation to viral release from the cell. The various targets for
Harald Brüssow
wiley +1 more source