The octapeptide repeats of prion protein play critical roles in the pathogenesis of prion diseases. [PDF]
Zhang X +11 more
europepmc +1 more source
CpG oligodeoxynucleotide reduces PrP<sup>Sc</sup> accumulation and prolongs survival in prion-infected mice. [PDF]
Mostafa MN +7 more
europepmc +1 more source
A model-based prion vaccine protects a transgenic mouse line carrying a Gerstmann-Sträussler-Scheinker disease mutation. [PDF]
Fang A +20 more
europepmc +1 more source
Mutant knock-in mice display enhanced susceptibility to pure prion protein fibrils. [PDF]
Walsh DJ +4 more
europepmc +1 more source
Consequences of prion strain mixtures: Indifference, competition, or collusion. [PDF]
Woerman AL, Bartz JC.
europepmc +1 more source
PrP<sup>C</sup>-facilitated cell signaling activates phospholipase Cɣ1 and triggers an Arc/Arg3.1 response in mouse and iPSC-derived human neurons. [PDF]
Ojeda-Juarez D +10 more
europepmc +1 more source
Comparison of acetone and sodium phosphotungstic acid precipitation for sample enrichment prior to RT-QuIC for the detection of prion disease. [PDF]
Nicholson EM, Veneziano SE.
europepmc +1 more source
Preclinical serum alterations and tissue changes in protein and gene expression of early cerebrospinal fluid-validated biomarkers in scrapie. [PDF]
Pérez-Lázaro S +4 more
europepmc +1 more source
Prion Diseases-When Proteins Turn Lethal: Creutzfeldt-Jakob Disease (CJD) and the Quest for Classification, Diagnosis, Therapeutic Approaches, and Emerging Research. [PDF]
Ramesh TS +3 more
europepmc +1 more source
Genetic Creutzfeldt-Jakob disease linked to the E200K mutation: a large cohort study. [PDF]
Appleby BS +8 more
europepmc +1 more source

