Results 191 to 200 of about 14,311 (225)

Antiviral Strategies against PRRSV Infection

Trends in Microbiology, 2017
PRRSV (porcine reproductive and respiratory syndrome virus) is a major economically significant pathogen that has adversely impacted the global swine industry for almost 30 years. Currently PRRSV is estimated to cause losses of almost US$600 million per year in the USA.
En-Min Zhou, Qin Zhao, Taofeng Du
exaly   +3 more sources

PRRSV genetic variation after the 2010 HP-PRRSV introduction in Thailand

The Thai Journal of Veterinary Medicine, 2016
After the first introduction of porcine reproductive and respiratory syndrome virus (PRRSV) into Thailand, Thai type 1 PRRSV has existed in the Thai swine population and caused subclinical diseases while type 2 PRRSV, which most PRRSV isolates belong to, has caused moderate to severe diseases.
Korakrit Poonsuk, Jirapat Arunorat, Nanthiya Iampraphat, Komkrich Teankum, Roongroje Thanawongnuwech   +4 more
openaire   +1 more source

Dynamics and evolution of porcine reproductive and respiratory syndrome virus (PRRSV) ORF5 following modified live PRRSV vaccination in a PRRSV-infected herd

Archives of Virology, 2013
The objective of this study was to investigate the dynamics and evolution of porcine reproductive and respiratory syndrome virus (PRRSV) ORF5 following the use of a modified live PRRSV (MLV) vaccine. A PRRSV-positive farm with coexistence of types 1 and 2 and no history of MLV vaccination was investigated.
Dachrit, Nilubol, Thitima, Tripipat, Tawatchai, Hoonsuwan, Pavita, Tipsombatboon, Jittima, Piriyapongsa   +4 more
openaire   +2 more sources

Arterivirus PRRSV

1998
Pigs were infected with the porcine respiratory and reproductive syndrome virus (PRRSV) by the oronasal route. We studied the development of histological lesions, sites of virus infection and of inflammatory infiltrates by quantitative evaluation of reactive cells. The animals developed a multifocal interstitial pneumonia.
J, Beyer, D, Fichtner, H, Schirrmeier, H, Granzow, U, Polster, E, Weiland, A, Berndt, H, Wege   +7 more
openaire   +2 more sources

Alterations in the expression level of visfatin in the lungs of piglets infected with PRRSV and its effect on PRRSV replication

Microbial Pathogenesis, 2022
Porcine reproductive and respiratory syndrome (PRRS) is a highly contagious disease caused by PRRS virus (PRRSV), characterized by sow reproductive failure and respiratory symptoms in pigs of all ages. PRRSV mainly causes severe lung damage by invading alveolar macrophages.
Zhe-wei Zhang, Abdur Rahman Ansari, Ling Dong, Xiao-yu Niu, Wen-jie Yang, Hui-zhen Li, Fen-liang Xu, Ke-li Yang, Hui Song   +8 more
openaire   +2 more sources

Broad neutralization activity against both PRRSV-1 and PRRSV-2 and enhancement of cell mediated immunity against PRRSV by a novel IgM monoclonal antibody

Antiviral Research, 2020
Porcine reproductive and respiratory syndrome (PRRS) is the most economically important infectious disease affecting the global swine industry, especially since vaccination has had limited impact on PRRSV prevention and control. In this study, the monoclonal antibody PR5nf1 (Mab-PR5nf1, IgM isotype) was shown to react with heterogeneous PRRSV isolates ...
Chunyan, Wu, Guoqian, Gu, Tianshu, Zhai, Yajing, Wang, Yongling, Yang, Yafei, Li, Xu, Zheng, Qin, Zhao, En-Min, Zhou, Yuchen, Nan   +9 more
openaire   +2 more sources

Presence of PRRSV in wild boar in Italy

Veterinary Record, 2006
SIR, – The wild boar ( Sus scrofa ) population in Italy has increased during the past 30 years, as it has in other European countries, such as Spain, France, Germany and Croatia. Direct or indirect contact between wild boar and domestic pigs ( Sus scrofa domesticus ) may occur occasionally ...
Paolo, Bonilauri, Giuseppe, Merialdi, Michele, Dottori, Ilaria, Barbieri   +3 more
openaire   +2 more sources

PRRSV receptors and their roles in virus infection

Archives of Microbiology, 2015
Porcine reproductive and respiratory syndrome virus (PRRSV) has a restricted cell tropism and prefers to invade well-differentiated cells of the monocyte/macrophage lineage, such as pulmonary alveolar macrophages and African green monkey kidney cell line MA-104 and its derivatives, such as Marc-145, Vero and CL-2621.
Chongxu, Shi, Yali, Liu, Yaozhong, Ding, Yongguang, Zhang, Jie, Zhang   +4 more
openaire   +2 more sources

Mechanistic Insights into PRRSV Inhibition through CD163–SRCR5 Blockade by PRRSV/CD163-IN-1

The Journal of Physical Chemistry Letters
Porcine reproductive and respiratory syndrome virus (PRRSV) causes severe economic losses in the swine industry by targeting pulmonary alveolar macrophages via the CD163 receptor, particularly its SRCR5 domain. However, the molecular details of small-molecule inhibition at this interface remain unclear.
Prawit Thitayanuwat, Kowit Hengphasatporn, Surang Chankhamhaengdecha, Yasuteru Shigeta   +3 more
openaire   +2 more sources

Packaged Heteroclite Subgenomic RNAs of PRRSV

2001
Porcine reproductive and respiratory syndrome virus (PRRSV) is a member of the Arteriviridae family of the Nidovirales (Meulenberg et al, 1993b; Nelsen et al., 1999). While the complete genomes of three PRRSV strains are known (Allende et al., 1999; Meulenberg et al., 1993; Nelsen et al., 1999), main questions remains to be elucidated concerning viral ...
S, Yuan, M P, Murtaugh, K S, Faaberg
openaire   +2 more sources