Results 201 to 210 of about 14,311 (225)
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Different expression patterns of PRRSV mediator genes in the lung tissues of PRRSV resistant and susceptible pigs

Developmental & Comparative Immunology, 2013
Porcine reproductive and respiratory syndrome (PRRS) has caused severe economic loss in most swine-producing countries. The resistance to PRRS virus (PRRSV) infection varies among pig breeds and lines. In this study, we found that the Chinese Dapulian pigs (DPL) were more resistant to PRRSV than commercial DurocĂ—LandraceĂ—Yorkshire (DLY) crossbred pigs ...
Chenglan, Jiang   +4 more
openaire   +2 more sources

Efficacy of Type 2 PRRSV vaccine against Chinese and Vietnamese HP-PRRSV challenge in pigs

Vaccine, 2014
Porcine reproductive and respiratory syndrome virus (PRRSV) causes significant reproductive losses in the sow herd and respiratory disease in growing pigs. The virus belongs to the family Arteriviridae and there are two major genotypes. Type 1 is represented by Lelystad virus, the European prototype virus, and Type 2 is represented by the North ...
Kelly M, Lager   +11 more
openaire   +2 more sources

Development of blocking ELISA for detection anti-PRRSV antibodies and serological investigation of PRRSV in China

International Journal of Biological Macromolecules
Porcine reproductive and respiratory syndrome virus (PRRSV) demonstrates a significantly high prevalence among swine populations. Monoclonal antibodies (mAbs) with high affinity for conserved epitopes of PRRSV can facilitate the development of a broad-spectrum detection method for this virus.
Shujie, Wang   +10 more
openaire   +2 more sources

Syndecan-4, a PRRSV attachment factor, mediates PRRSV entry through its interaction with EGFR

Biochemical and Biophysical Research Communications, 2016
The causative agent of porcine reproductive and respiratory syndrome is the PRRS virus (PRRSV), an enveloped, single-stranded and positive-sense RNA virus. The host factors and mechanisms that are involved in PRRSV entry are still largely unknown.
Rui, Wang   +10 more
openaire   +2 more sources

The mRNA vaccine expressing fused structural protein of PRRSV protects piglets against PRRSV challenge

Veterinary Microbiology
The swine industry experiences substantial economic losses annually due to the porcine reproductive and respiratory syndrome virus (PRRSV). The limited protective efficacy of existing commercial vaccines against epidemic PRRSV underscores the urgent need for innovative solutions.
Chunxiao, Mou   +8 more
openaire   +2 more sources

Genetic Variations of Thai PRRSV after the 2010 HP-PRRSV Outbreak in Thailand

Since multiple HP-PRRSV outbreaks occurred in Thailand in 2010, PRRSV infection was one of major reasons for economic losses in the Thai swine industry. To improve knowledge about the disease and effects of novel PRRSV isolates introduced in Thailand, comparative analysis and genetic characteristics of the hyper-variable regions, NSP2 and ORF5, of ...
openaire   +1 more source

Nucleic acids encoding TGEV and PRRSV sequences for improved expression of PRRSV sequences

2011
The present invention relates to nucleic acids comprising: (a) sequences of a replication competent transmissible gastroenteritis virus (TGEV), which sequences encode a TGEV replicase under the control of expression regulatory sequences, wherein the replicase is expressed in a host cell and will initiate replication of the nucleic acid and thus ...
CONSEJO SUPERIOR INVESTIGACION   +1 more
openaire   +1 more source

Matrine exhibits antiviral activity in a PRRSV/PCV2 co-infected mouse model

Phytomedicine, 2020
Hua Zhang, Hongquan Li, Na Sun
exaly  

Efficacy of PRRSV vaccination regimens to overcome maternal immunity in PRRSV-positive weaned pigs

AASV Annual Meeting, 2023
A. Steffensmeier   +5 more
openaire   +1 more source

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