Results 11 to 20 of about 6,818 (208)

Easy-PSAP: An Integrated Workflow to Prioritize Pathogenic Variants in Sequence Data from a Single Individual

Human Heredity
Introduction: Next-generation sequencing (NGS) data analysis has become an integral part of clinical genetic diagnosis, raising the question of variant prioritization.
Marie-Sophie C. Ogloblinsky, Marc B. Gros-La-Faige, Daniel P. Lewinsohn, Mathilde Nguyen, Lourdes Velo-Suarez, Anthony Herzig, Thomas E. Ludwig, Helen Castillo-Madeen, Donald F. Conrad, Emmanuelle Génin, Gaëlle Marenne   +10 more
doaj   +2 more sources

Association analysis of PSAP variants in Parkinson’s disease patients [PDF]

Brain, 2020
National Research Foundation (NRF)
Yin Xia Chao, Bernett Lee, Ebonne Yulin Ng, Michelle Mulan Lian, Elaine Guo Yan Chew, Moses Tandiono, Zheng Li, Chiea Chuen Khor, Prakash Kumar, Louis C S Tan, Jia Nee Foo, Eng-King Tan   +11 more
openaire   +4 more sources

RNPS1 in PSAP complex controls periodic pre-mRNA splicing over the cell cycle

iScience
Summary: Cell cycle progression requires periodic gene expression through splicing control. However, the splicing factor that directly controls this cell cycle-dependent splicing remains unknown.
Kazuhiro Fukumura, Akio Masuda, Jun-ichi Takeda, Osamu Nagano, Hideyuki Saya, Kinji Ohno, Akila Mayeda   +6 more
doaj   +2 more sources

The expression of prosaposin and its receptors, GRP37 and GPR37L1, are increased in the developing dorsal root ganglion.

PLoS ONE, 2021
Prosaposin (PSAP), a highly conserved glycoprotein, is a precursor of saposins A-D. Accumulating evidence suggests that PSAP is a neurotrophic factor, as well as a regulator of lysosomal enzymes. Recently, the orphan G-protein-coupled receptors GPR37 and
Miho Taniguchi, Hiroaki Nabeka, Kimiko Yamamiya, Md Sakirul Islam Khan, Tetsuya Shimokawa, Farzana Islam, Takuya Doihara, Hiroyuki Wakisaka, Naoto Kobayashi, Fumihiko Hamada, Seiji Matsuda   +10 more
doaj   +2 more sources

Pain and Sleep Disturbances are Associated with Post-stroke Anger Proneness and Emotional Incontinence [PDF]

Rehabilitacja Medyczna, 2023
Background: Emotional disorders are common findings after a stroke episode. Despite evidence linking pain and sleep disorders tovarious post-stroke emotional conditions, their roles in the prevalence of post-stroke anger proneness (PSAP) and post-stroke ...
Adekola B. Ademoyegun, Wasiu A. Rasaq, Omotola I. Adelowokan, Victor A. Afolabi, Adebukola G. Ibitoye, Taofeek O. Awotidebe, Chidozie E. Mbada   +6 more
doaj   +1 more source

eCall receiving: The PSAP operator user experience

, 2012
The development of eCall is moving towards deployment but there have been very little discussion from the PSAP operator perspective. As a part of TeleFOT project a detailed test was conducted to gather the first impression of a PSAP operator about eCall ...
Kulju, Minna, Aaltonen, Jukka, Tarkiainen, Mikko   +3 more
core   +5 more sources

Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents

Nature Communications, 2023
Prosaposin (PSAP) modulates glycosphingolipid metabolism and variants have been linked to Parkinson’s disease (PD). Here, we find altered PSAP levels in the plasma, CSF and post-mortem brain of PD patients.
Yachao He, Ibrahim Kaya, Reza Shariatgorji, Johan Lundkvist, Lars U. Wahlberg, Anna Nilsson, Dejan Mamula, Jan Kehr, Justyna Zareba-Paslawska, Henrik Biverstål, Karima Chergui, Xiaoqun Zhang, Per E. Andren, Per Svenningsson   +13 more
doaj   +1 more source

Relación de la presión sistólica de la arteria pulmonar medida por ecocardiograma con el tiempo y el tipo de terapia de reemplazo renal

Revista Colombiana de Cardiología, 2022
Introducción: Las alteraciones secundarias a la enfermedad renal crónica (ERC), como inflamación sistémica, anemia y sobrecarga hídrica, son un sustrato importante para el desarrollo de hipertensión arterial pulmonar.
María J. Pérez-López, Alejandro Glover-Aguilar, Bibiana López-López, Isaí T. Cuamba-Nambo, Lilia Granados-Ventura, Joaquín Vargas-Peñafiel, Jorge H. Jiménez-Orozco, Juan C. Hernández-Rivera   +7 more
doaj   +1 more source

Prolonged antibiotic prophylaxis use in elective orthopaedic surgery – a cross-sectional analysis

BMC Musculoskeletal Disorders, 2021
Purpose Surgical antibiotic prophylaxis (SAP) prevents surgical site infections (SSI). In orthopaedic surgery, the use of prolonged SAP (PSAP) has been reported in daily routine, despite guidelines advising against it.
Felix Rohrer, Anita Maurer, Hubert Noetzli, Brigitta Gahl, Andreas Limacher, Tanja Hermann, Jan Bruegger   +6 more
doaj   +1 more source

Structure of PSAP and the IM-1 antibody.

, 2021
An anti-rat PSAP-specific antibody (IM-1) was prepared against the proteolytic portion (the intermediate portion between saposins C and D) of PSAP.
Tetsuya Shimokawa (485032), Miho Taniguchi (11261679), Naoto Kobayashi (485033), Hiroyuki Wakisaka (740748), Takuya Doihara (569215), Seiji Matsuda (485036), Fumihiko Hamada (29532), Farzana Islam (9713464), Hiroaki Nabeka (485031), Kimiko Yamamiya (668075), Md. Sakirul Islam Khan (9713461)   +10 more
core   +1 more source