Effect of Pseudomonas aeruginosa exotoxin A on inner ear function
, 1997 Electrophysiological changes were studied in the albino rat following instillation of Pseudomonas aeruginosa exotoxin A into the middle ear cavity through the tympanic membrane.
Pettersson, Åke, +2 more
core +8 more sources
PCR based identification of exotoxin A-producing Pseudomonas aeroginosa isolated from burn wound infection [PDF]
Trends in Pharmaceutical Sciences, 2022 Exotoxin A (exoA) is a major pathogenic factor in Pseudomonas aeruginosa. This non-fermenting gram-negative bacillus causes a wide range of infections. P. aeruginosa is a major cause of hospital-acquired infections.
Gholamreza Morshedi +9 more
doaj +1 more source
Molecular Characterization of Virulence genes in Pseudomonas Species Isolated from Bulk tank Milk in El Menofia Governorate [PDF]
Benha Veterinary Medical Journal, 2023 Pseudomonas is a genus of Gram-negative bacteria belonging to the family Pseudomonadaceae. It is one of the psychrophilic bacteria that can thrive in low temperature milk in addition to producing heat-resistant spoiling enzymes due to presence of ...
Rasha Deiab +2 more
doaj +1 more source
Preparation and evaluation of the exotoxin A nano-gold conjugate as a vaccine candidate for Pseudomonas aeruginosa infections [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): Pseudomonas aeruginosa is an opportunistic pathogen that is an important cause of nosocomial infections. This bacterium produces various virulence factors, among which exotoxin A is significantly involved in mortality and morbidity. In this
Masoumeh Abbasi +4 more
doaj +1 more source
ISOLATION AND PURIFICATION OF ANTICANCER PROTEIN EXOTXIN A FROM Pseudomonas aeruginosa
The Iraqi Journal of Agricultural science, 2022 Toxins produced from bacteria constitute promising antitumor agents in treating different cancer types. Exotoxin A from Pseudomonas aeruginosa is the highly toxic virulence component that bind to specific cell receptors.
L. Q. Jawad, H. A. R. R. Rasheed
doaj +1 more source
Rhus coriaria extracts inhibit quorum sensing related virulence and biofilm production in drug-resistant Pseudomonas aeruginosa recovered from burn wounds [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): Numerous studies have confirmed sumac’s ability to inhibit pathogens and even eradicate chronic drug-resistant infections. Current research was conducted to demonstrate the action of various sumac extracts at sub-inhibitory concentrations ...
Akhter Ahmed +2 more
doaj +1 more source
LINK BETWEEN SOME VIRULNCE FACTORS GENES AND ANTIBACTERIAL RESISTANCE OF PSEUDOMONAS AERUGINOSA
The Iraqi Journal of Agricultural science, 2022 The research was aimed to demonstrate the frequency of virulence factors genes (exoenzyme S and exotoxin A) and to express their relationship to antibacterial resistance among Pseudomonas aeruginosa isolated from patients suffering from otitis externa ...
Aida H. Ibrahim
doaj +1 more source
BMC Infectious Diseases, 2021 Background Pseudomonas aeruginosa is the leading cause of nosocomial infections, especially in people with a compromised immune system. Targeting virulence factors by neutralizing antibodies is a novel paradigm for the treatment of antibiotic-resistant ...
Zahra Shadman +6 more
doaj +1 more source
AMB Express, 2021 This work explores the ADP-ribosyltransferase activity of Pseudomonas (P.) aeruginosa exotoxin A using the guanyl hydrazone derivative, nitrobenzylidine aminoguanidine (NBAG) and the impact of gamma radiation on its efficacy.
Radwa N. Morgan +3 more
doaj +1 more source
Retrograde transport pathways utilised by viruses and protein toxins [PDF]
, 2006 A model has been presented for retrograde transport of certain toxins and viruses from the cell surface to the ER that suggests an obligatory interaction with a glycolipid receptor at the cell surface. Here we review studies on the ER trafficking cholera
J Michael Lord +9 more
core +1 more source