Pseudomonas infection: exotoxin A effect [PDF]
Саратовский научно-медицинский журнал, 2014 The aim of the article is to present the data analysis of the Russian and foreign literature concerning the current situation of the problem, the frequency and mechanisms of pseudomonas infection development and factors of patho-genicity of Pseudomonas ...
Morrison A.V. +2 more
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Exotoxin A Pseudomonas aeruginosa influence on working efficiency of white rats [PDF]
Саратовский научно-медицинский журнал, 2017 Objective: to study exotoxin A Pseudomonas aeruginosa influence on physical and mental efficiency of white rats. Material and Methods. The experiments were carried out on white rats following intraperitoneal injections of exotoxin A Pseudomonas of ...
Morrison V.V. +3 more
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Pseudomonas aeruginosa exotoxin A-induced hepatotoxicity in dynamics: an animal model in white mice [PDF]
Саратовский научно-медицинский журнал, 2015 Purpose: to study biochemical indices of peripheral blood which show organs functional changes. Material and Methods. The experiments were carried out on white mice in dynamics development of pseudomonas aeruginosa caused by intraperitoneal injection of ...
Morrison A.V. +2 more
doaj +1 more source
Determining Induction Conditions for Expression of Truncated Diphtheria Toxin and Pseudomonas Exotoxin A in E. coli BL21 [PDF]
Novelty in Biomedicine, 2018 Background: Targeted cancer therapies have played a great role in the treatment of malignant tumors, in the recent years. Among these therapies, targeted toxin therapies such as immunotoxins, has improved the patient’s survival rate by minimizing the ...
Sahel Amoozadeh +4 more
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Armaghane Danesh Bimonthly Journal, 2008 Introduction & Objective: Pseudomonas aeruginosa is a gram negative bacterial. This bacterium is resistant to many antibiotics and chemical disinfectants.
M Naghmachi, A Sharifi, J Kohanteb
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LRP1B functions as a receptor for Pseudomonas exotoxin [PDF]
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2005 Pseudomonas aeruginosa is an opportunistic pathogen that produces several virulence factors, among them Pseudomonas Exotoxin A (PE). Previously, low-density lipoprotein receptor-related protein 1 (LRP 1) was shown to be the primary receptor for PE. In this report, we show that a close family member, LRP 1B, can also function as a receptor.
Pastrana, Diana V. +4 more
openaire +4 more sources
The Immunomodulatory Effect of Recombinant Exotoxin A of Pseudomonas Aeruginosa on Dendritic Cells Extracted from Mice Spleen [PDF]
Journal of Advanced Biomedical Sciences, 2014 Background & Objective: Dendritic cell (DC) is as a key cell in activation of immune response against microbes and disease. Therefore, the effect of recombinant exotoxin A of Pseudomonas aeruginosa on the maturity and the activation of DCs was evaluated ...
Mohammad Hossein Karimi +3 more
doaj +1 more source
Pseudomonas Exotoxin A Based Toxins Targeting Epidermal Growth Factor Receptor for the Treatment of Prostate Cancer [PDF]
Toxins, 2020 Philipp Wolf +2 more
exaly +2 more sources
Active immunization using exotoxin A confers protection against
BMC Microbiology, 2009 Background Pseudomonas aeruginosa is an important cause of nosocomial infection and may lead to septicemia and death. We evaluated the immunogenicity of semi-purified exotoxin A from the bacterium in a mouse burn model.
Naghmachi Mohsen +7 more
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Cloning and expression of the immunogenic moiety of Pseudomonas aeruginosa exotoxin A
Biological Journal of Microorganism, 2013 Introduction: Pseudomonas aeruginosa, as an opportunistic microorganism, is a major cause of nosocomial infections worldwide. Exotoxin A (ETA) is an extracellular enzyme that is produced by most clinical strains of P. aeruginosa.
Sahar Nouri Gharajelar * +2 more
doaj +1 more source