Detection of Exotoxins and Antimicrobial Susceptibility Pattern in Clinical Pseudomonas Aeruginosa Isolates [PDF]
, 2017 Background: Pseudomonas aeruginosa is a common opportunistic pathogen that causes nosocomial infection in immunocompromised patients. Among different virulence factors, the type III secretion system (TTSS) is an important agent in virulence and ...
Deris, Fatemeh. +4 more
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Pseudomonas aeruginosa exotoxin A-induced hepatotoxicity in dynamics: an animal model in white mice [PDF]
Саратовский научно-медицинский журнал, 2015 Purpose: to study biochemical indices of peripheral blood which show organs functional changes. Material and Methods. The experiments were carried out on white mice in dynamics development of pseudomonas aeruginosa caused by intraperitoneal injection of ...
Morrison A.V. +2 more
doaj
Early detection of – comparison of conventional versus molecular (PCR) detection directly from adult patients with cystic fibrosis (CF) [PDF]
, 2004 Background Pseudomonas aeruginosa (PA) is the most important bacterial pathogen in patients with cystic fibrosis (CF) patients. Currently, routine bacteriological culture on selective/non- selective culture media is the cornerstone of microbiological ...
Jiru Xu +4 more
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Exotoxin production by clinical isolates of pseudomonas aeruginosa [PDF]
Infection and Immunity, 1977 Seventy-five consecutive clinical Pseudomonas aeruginosa isolates were tested for in vitro exotoxin production. Exotoxin was demonstrated in culture filtrates biologically, by its ability to produce characteristic dermonecrotic lesions in guinea pigs, and seriologically, by counterimmunoelectrophoresis (CIE) with rabbit antiserum elicited with purified
M, Pollack, N S, Taylor, L T, Callahan
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Angewandte Chemie, Volume 138, Issue 6, 2 February 2026.A total of 16 chemically synthesized capsular polysaccharide (CPS) fragments related to Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii were analyzed by glycan microarray. Comparative screening revealed three conserved epitopes that act as cross‐protective vaccine lead candidates against multidrug‐resistant (MDR) bacterial ...
Amar Kumar Mishra +9 more
wiley +2 more sources
Bacteria in cancer therapy: a novel experimental strategy [PDF]
, 2010 Resistance to conventional anticancer therapies in patients with advanced solid tumors has prompted the need of alternative cancer therapies. Moreover, the success of novel cancer therapies depends on their selectivity for cancer cells with limited ...
S Patyar +5 more
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Aspergillus fumigatus enhances elastase production in pseudomonas aeruginosaco-cultures [PDF]
, 2015 In the cystic fibrosis (CF) lung the presence of bacteria and fungi in the airways promotes an inflammatory response causing progressive lung damage, ultimately leading to high rates of morbidity and mortality.
Kerr, Stephen +6 more
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Toxicity of Pseudomonas aeruginosa exotoxin A for human macrophages [PDF]
Infection and Immunity, 1978 Pseudomonas aeruginosa exotoxin A was toxi in vitro for human peripheral blood macrophages. Cytotoxicity, manifested by morphological evidence of cell death and inhibition of [3H]thymidine uptake, followed exposure to as little as 10 ng of exotoxin per ml for 1 h.
M, Pollack, S E, Anderson
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Sepsis caused by bloodstream infection in patients in the intensive care unit: the impact of inactive empiric antimicrobial therapy on outcome [PDF]
, 2018 Background: Sepsis is one of the leading causes of death in the UK. Aims: The aims of this study were to identify the rate of inactive antimicrobial therapy (AMT) in the ICU and whether inactive AMT had an effect on in hospital mortality, ICU ...
Booth, M.G. +4 more
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Transcription and Expression of the Exotoxin A Gene of Pseudomonas aeruginosa [PDF]
Microbiology, 1987 The exotoxin A genes from Pseudomonas aeruginosa strains PA103 and PAO1 have been independently cloned in a pUC9-derived plasmid. In a non-toxigenic mutant of PAO1 as host, the cloned genes directed the synthesis of intact exotoxin A that expressed ADP-ribosyltransferase activity upon treatment with urea and dithiothreitol.
S T, Chen +4 more
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