Results 101 to 110 of about 8,243 (225)

Activation of Spinal Astrocyte α2A Adrenoceptors Protects Against Sepsis‐Induced Heart Injury Through Inhibition of GABAergic Neuronal Necroptosis

Advanced Science, Volume 12, Issue 39, October 20, 2025.
The study in this paper found that activating the α2A receptors of astrocytes in the thoracic spinal cord can reduce the release of inflammatory factors, thereby decreasing the necroptosis of GABAergic neurons and consequently alleviating myocardial injury caused by sepsis.
Ruilin He, Bin Wu, Liuhu Han, Mingde Li, Wenli Guo, Jiajing Fu, Bin Mei, Eric R. Gross, Xuesheng Liu, Yao Lu   +9 more
wiley   +1 more source

Development of a Ready‐To‐Use Bioluminescence Immunosensor for the One‐Step Sensitive Detection of Antibodies Against African Swine Fever Virus

Microbial Biotechnology, Volume 18, Issue 10, October 2025.
A ready‐to‐use bioluminescence immunosensor for rapid, one‐step detection of ASFV antibodies, offering high specificity, high sensitivity, and ease of use, with promising applications for point‐of‐care diagnostics. ABSTRACT Rapid and reliable analytical techniques play important roles in various research fields and are particularly crucial for ...
Zhonghui Zhang, Xuesai Li, Qingli Niu, Jinming Wang, Yanghe Liu, Dossêh Jean Apôtre Afayibo, Wenting Chen, Songlin Yang, Hong Yin, Guiquan Guan, Jifei Yang   +10 more
wiley   +1 more source

The caudal pedunculopontine tegmental nucleus may be involved in the regulation of skeletal muscle activity by melanocortin-sympathetic pathway: a virally mediated trans-synaptic tracing study in spinally transected transgenic mice [PDF]

, 2017
Understanding neuroanatomical sympathetic circuitry and neuronal connections from the caudal pedunculopontine tegmental nucleus to skeletal muscle is important to the study of possible mechanisms of pedunculopontine tegmental nucleus (PPTg) and cuneiform
He, Zhi-Gang, Li, Zhi-Xiao, Liu, Bao-Wen, Liu, San-Guang, Manyande, Anne, Tian, Xuebi, Xiang, Hong-Bing, Zhang, Ding-Yu   +7 more
core   +1 more source

Splanchnic and Pelvic Spinal Afferent Pathways Relay Sensory Information From the Mouse Colorectum Into Distinct Brainstem Circuits

Journal of Neurochemistry, Volume 169, Issue 9, September 2025.
This study used transneuronal viral tracer to identify the spinal cord and brainstem circuits connected to the colorectum in the mouse (A). To establish if the regions of the brainstem labelled from the colon were functionally relevant to colorectal sensory‐motor processing, the distribution of neurons activated by distending the colon was mapped (B ...
QingQing Wang, Alice E. McGovern, Melinda Kyloh, Grigori Rychkov, Nick J. Spencer, Stuart B. Mazzone, Stuart M. Brierley, Andrea M. Harrington   +7 more
wiley   +1 more source

Global transcriptional response of pig brain and lung to natural infection by Pseudorabies virus. [PDF]

, 2011
BACKGROUND: Pseudorabies virus (PRV) is an alphaherpesviruses whose native host is pig. PRV infection mainly causes signs of central nervous system disorder in young pigs, and respiratory system diseases in the adult.
Affara, NA, Chausiaux, OE, Furlong, RA, Jafer, O, Sargent, CA, Yuan, JF, Zhang, GH, Zhang, SJ   +7 more
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A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale [PDF]

, 2009
In this era of complete genomes, our knowledge of neuroanatomical circuitry remains surprisingly sparse. Such knowledge is however critical both for basic and clinical research into brain function. Here we advocate for a concerted effort to fill this gap,
A MacKenzie-Graham, A Reiner, A Vercelli, A Visel, Allan Jones, AM Hattox, Arthur W. Toga, AW Toga, AY Hardan, B Egaas, B Horwitz, BL Davidson, Brett D. Mensh, Bruce W. Stillman, C Gustafson, C Kobbert, Caizhi Wu, CL Veenman, Claus C. Hilgetag, Clifford B. Saper, CR Gerfen, D Atasoy, DA Benson, Daniel G. Herrera, David C. Van Essen, David Kleinfeld, DC Van Essen, DC Van Essen, DL Sparks, E Miyashita, ED Jarvis, Edward G. Jones, EM Callaway, ES Lein, ET Bullmore, F Castelli, F Crick, G Aston-Jones, H Markram, Hans C. Breiter, Harvey J. Karten, HC Breiter, Helen Barbas, Hemant Bokil, Henry A. Lester, Hollis T. Cline, IR Wickersham, J DeFalco, J Dejerine, J Panksepp, J Panksepp, Jaak Panksepp, James D. Watson, Jason W. Bohland, JD Schmahmann, Jeremy D. Schmahmann, JF Démonet, JG Bjaalie, JG Bjaalie, JG Bjaalie, JG White, JL Lanciego, JM Lin, John C. Doyle, John M. Lin, Joseph L. Price, Joseph Safdieh, K Oishi, K Wernicke, Karel Svoboda, KE Stephan, KE Stephan, L Ng, L Stein, Larry W. Swanson, LM Coolen, M Bota, M Bota, M Bota, M Murias, MA Just, MD Johnson, MI Ekstrand, Michael Hawrylycz, Mihail Bota, MJ Swift, N Geschwind, Nicholas D. Schiff, O Sporns, Olaf Sporns, Partha P. Mitra, Peter J. Freed, PH Luppi, PJ Broser, R Kotter, R Kotter, Ralph J. Greenspan, RH Güting, RM Kelly, Rolf Kötter, RW Baughman, S Folstein, S Lillehaug, S Mikula, Shawn Mikula, Suzanne N. Haber, U Burgel, U Frith, V Grinevich, Z. Josh Huang   +109 more
core   +9 more sources

Adducin‐1 Facilitates Influenza Virus Endosomal Trafficking and Uncoating by Regulating Branched Actin Dynamics and Myosin IIB Activity

Advanced Science, Volume 12, Issue 28, July 24, 2025.
In this study, a novel mechanism is unveiled by which ADD1, acting as a molecular switch, coordinates actin branch dynamics and the transport of endocytic viruses and cargoes. Phosphorylation of ADD1 at Ser726 reduces actin branch density, enhancing endosome fusion and attachment to microtubules.
Meijun Jiang, Jiahui Zou, Yaoming Jin, Chenjun Jiang, Shaoyu Tu, Tong Chen, Jinli Guo, Yanqing Cheng, Meilin Jin, Huanchun Chen, Hongbo Zhou   +10 more
wiley   +1 more source

DNA aptamers targeting glycoprotein D enable specific detection of pseudorabies virus (PRV)

Animal Diseases
Abstract Pseudorabies virus (PRV, SuidAlphaherpesvirus 1) causes substantial economic losses in swine production. Here, we report the development of DNA aptamers targeting the PRV glycoprotein D (gD) through an optimized SELEX protocol. After 15 selection cycles, Apt-gD-2 demonstrated nanomolar affinity (Kd = 6.107 ± 0.476 nM) and high ...
Zhihao Wang, Yan Qiao, Jiafu Zhao, Xiaotian Chang, Heshui Zhu, Chao Zhang   +5 more
openaire   +2 more sources

Pseudorabies virus hijacks the Rab6 protein to promote viral assembly and egress

Veterinary Research
Pseudorabies virus (PRV) is recognized as the aetiological agent responsible for Aujeszky’s disease, or pseudorabies, in swine populations. Rab6, a member of the small GTPase family, is implicated in various membrane trafficking processes, particularly ...
Dong-Ge Liang, Yu-Kun Guo, Shi-Bo Zhao, Guo-Yu Yang, Ying-Qian Han, Bei-Bei Chu, Sheng-Li Ming   +6 more
doaj   +1 more source

Iowa Animal Industry News, 2012, Vol. 14, no. 1 [PDF]

, 2012
Newsletter produced by Department of Agriculture and Land Stewardship about the animal industry in Iowa.Previously titled Animal Industry ...

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