Results 141 to 150 of about 1,720,439 (181)

Predicting Pseudouridine Sites with Porpoise

2023
Pseudouridine is a ubiquitous RNA modification and plays a crucial role in many biological processes. However, it remains a challenging task to identify pseudouridine sites using expensive and time-consuming experimental research. To this end, we present Porpoise, a computational approach to identify pseudouridine sites from RNA sequence data. Porpoise
Xudong, Guo, Fuyi, Li, Jiangning, Song
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The pseudouridine residues of ribosomal RNA

Biochemistry and Cell Biology, 1995
Pseudouridine (Ψ), the most common single modified nucleoside in ribosomal RNA, has been positioned in the small subunit (SSU) and large subunit (LSU) RNAs of a number of representative species. Most of the information has been obtained by application of a rapid primed reverse transcriptase sequencing technique.
J, Ofengand, A, Bakin, J, Wrzesinski, K, Nurse, B G, Lane   +4 more
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The Chemistry of Pseudouridine

1966
Publisher Summary This chapter discusses the chemistry of pseudouridine, leaving the biological properties for a companion review. It points out the unique chemical features of pseudouridine and an attempt to rationalize them in terms of modern organic chemistry.
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Pseudouridine: A Biochemical Marker for Cancer

1984
Although some progress has been made in clarifying the molecular basis underlying neoplastic transformation, antineoplastic treatment is still based on the effort toward the removal of all neoplastic cells. In this respect, the most important requirement for the effectiveness of treatment is the precocious diagnosis, possibly in the preclinical period.
CIMINO, FILIBERTO, RUSSO, TOMMASO, COLONNA, ALFREDO, SALVATORE, FRANCESCO   +3 more
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Pseudouridine Chemical Labeling and Profiling

2015
Pseudouridine (Ψ) is the most abundant posttranscriptional RNA modification; yet little is known about its prevalence and function in messenger RNA, mostly due to the challenges in the transcriptome-wide detection of Ψ. Here, we report CeU-Seq-a selective chemical labeling and pull-down method for the comprehensive analysis of transcriptome-wide ...
Xiaoyu, Li, Shiqing, Ma, Chengqi, Yi
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Structure and conformation of pseudouridine analogs

Biochemistry, 1981
The structural and conformational features of the "anomeric" DL-trans- and DL-cis-5-(3-hydroxytetrahydrofuran-2-yl)uracils (3a, 4a) and five similar analogues were studied in order to determine their applicability as models of beta- and alpha-pseudouridine.
R L, Lipnick, J D, Fissekis, J P, O'Brien   +2 more
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attempted prebiotic synthesis of pseudouridine

Origins of life and evolution of the biosphere, 1997
Pseudouridine is a modified base found in all tRNA and rRNA. Hence, it is reasonable to think that pseudouridine was important in the early evolution, if not the origin, of life. Since uracil reacts rapidly with formaldehyde and other aldehydes at the C-5 position, it is plausible that pseudouridine could be synthesized in a similar way by the reaction
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Detection and Quantification of Pseudouridine in RNA

2018
Pseudouridylation is the most abundant of all RNA modifications. Pseudouridylation is dynamic and widespread among many different types of RNAs in living organisms, thus drawing a lot of recent interest from the RNA and epigenetics communities. To successfully carry out an investigation into RNA pseudouridylation, it is desirable to have a convenient ...
Hironori, Adachi, Meemanage D, DeZoysa, Yi-Tao, Yu   +2 more
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ChemInform Abstract: Pseudouridine.

ChemInform, 1998
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A. HEMPEL, B. G. LANE, N. CAMERMAN
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Cyclo-pseudouridine and the Configuration of Pseudouridine

Biochemistry, 1962
A M, MICHELSON, W E, COHN
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