Results 111 to 120 of about 431,100 (179)

Crystal structure of the catalytic domain of RluD, the only rRNA pseudouridine synthase required for normal growth of Escherichia coli

, 2004
Escherichia coli pseudouridine synthase RluD makes pseudouridines 1911, 1915, and 1917 in the loop of helix 69 in 23S RNA. These are the most highly conserved ribosomal pseudouridines known. Of 11 pseudouridine synthases in E.
Malhotra, Arun, Ofengand, James, Del Campo, Mark   +2 more
core   +1 more source

Assembly of the eukaryotic PLP-synthase complex from plasmodium and activation of the Pdx1 enzyme [PDF]

, 2012
Biosynthesis of vitamins is fundamental to malaria parasites. Plasmodia synthesize the active form of vitamin B6 (pyridoxal 5-phosphate, PLP) using a PLP synthase complex.
Böttcher, Bettina, Derrer, Bianca, Windeisen, Volker, Hipp, Katharina, Tews, Ivo, Sinning, Irmgard, Kappes, Barbara, Boettcher, Bettina, Gengenbacher, Martin, Guedez, Gabriela   +9 more
core   +1 more source

Global mapping of pseudouridine in the transcriptomes of \(Campylobacter\) \(jejuni\) and \(Helicobacter\) \(pylori\) and functional characterization of pseudouridine synthases

, 2023
Mehr als 150 verschiedene RNA-Modifikationen sind bislang in den unterschiedlichsten Organismen nachgewiesen worden, wovon 60 dieser Modifikationen in bakterieller RNA vorkommen. In Bakterien ist Pseudouridin eine der häufigsten Modifikationen, die in stabilen RNAs wie tRNAs und rRNAs zu finden sind.
openaire   +1 more source

Causal Relationship Between Mitochondrial Characteristics and Inflammatory Bowel Disease and Its Subtypes: Evidence for Mendelian Randomization

JGH Open
Objective The research was designed to explore the causal relationship between the changing landscape of 63 mitochondrial proteins and inflammatory bowel disease (IBD) by Mendelian randomization.
Yichen Cai, Hancheng Fan, Jianmin Zhao, Guoxiang Fu   +3 more
doaj   +1 more source

Substrate binding and catalysis by the pseudouridine synthases RluA and TruB [PDF]

, 2012
xi, 122 leaves : ill. (some col.) ; 29 cmPseudouridine is the most common RNA modification found in all forms of life. The exact role pseudouridines play in the cell is still relatively unknown.
Keffer-Wilkes, Laura C.
core  

mt-LAF3 is a pseudouridine synthase ortholog required for mitochondrial rRNA and mRNA gene expression in Trypanosoma brucei. [PDF]

Int J Parasitol, 2023
McDermott SM, Pham V, Lewis I, Tracy M, Stuart K.   +4 more
europepmc   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Identification of allele specific function of Candida ablicans Pseudouridine Synthase 4 [PDF]

, 2018
Candida albicans is the most prevalent human fungal pathogen. Unfortunately, there still remains much that is unknown about it, including the reason for maintaining a diploid genome and the function of many genes.
Embree, Caleb
core  

DKC1: a robust prognostic factor and potential therapeutic target in multiple myeloma

Journal of Translational Medicine
Background Multiple myeloma (MM) is an incurable plasma cell malignancy. Dyskerin pseudouridine synthase 1 (DKC1), a nucleolar protein, is essential for RNA modification and cellular homeostasis, yet its role in MM remains unclear.
Chenxi Sun, Lin Cheng, Ai Li, Yanxiao Han, Yongjing Wang, Juan Xiao, Yanan Guo, Wenting Zhang, Likun Sun, Dawei Xu, Dexiao Kong, Yang Jiang, Chengyun Zheng   +12 more
doaj   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source