Results 31 to 40 of about 2,780 (214)

The varieties of the psychedelic experience: A preliminary study of the association between the reported subjective effects and the binding affinity profiles of substituted phenethylamines and tryptamines [PDF]

open access: yes, 2018
Classic psychedelics are substances of paramount cultural and neuroscientific importance. A distinctive feature of psychedelic drugs is the wide range of potential subjective effects they can elicit, known to be deeply influenced by the internal state of
Erowid, Earth   +6 more
core   +2 more sources

Proposal of 5-methoxy-N-methyl-N-isopropyltryptamine consumption biomarkers through identification of in vivo metabolites from mice [PDF]

open access: yes, 2017
New psychoactive substances (NPS) are a new breed of synthetically produced substances designed to mimic the effects of traditional illegal drugs. Synthetic cannabinoids and synthetic cathinones are the two most common groups, which try to mimic the ...
Barneo-Muñoz, Manuela   +5 more
core   +2 more sources

Toxicological Analysis of Some Drugs of Abuse in Biological Samples [PDF]

open access: yes, 2015
Consumption of drugs of abuse is a scourge of modern world. Abuse, drug addiction and their consequences are one of the major current problems of European society because of the significant repercussions in individual, family, social and economic level ...
Baconi, Daniela Luiza   +5 more
core   +3 more sources

Return of the lysergamides. Part IV: Analytical and pharmacological characterization of lysergic acid morpholide (LSM-775) [PDF]

open access: yes, 2018
Lysergic acid diethylamide (LSD) is perhaps one of the best-known psychoactive substances and many structural modifications of this prototypical lysergamide have been investigated. Several lysergamides were recently encountered as “research chemicals” or
Abramson   +67 more
core   +1 more source

Optimization through a Box–Behnken Experimental Design of the Microwave-Assisted Extraction of the Psychoactive Compounds in Hallucinogenic Fungi (Psylocibe cubensis)

open access: yesJournal of Fungi, 2022
Hallucinogenic fungi, mainly those from the Psilocybe genus, are being increasingly consumed even though there is no control on their culture conditions.
Curro Polo-Castellano   +5 more
doaj   +1 more source

Psychedelics and Immunomodulation: novel Approaches and Therapeutic Opportunities [PDF]

open access: yes, 2017
Classical psychedelics are psychoactive substances, which, besides their psychopharmacological activity, have also been shown to exert significant modulatory effects on immune responses by altering signaling pathways involved in inflammation, cellular ...
Szabó, Attila
core   +4 more sources

Psilocybin for Treating Psychiatric Disorders: A Psychonaut Legend or a Promising Therapeutic Perspective?

open access: yesJournal of Xenobiotics, 2022
Psychedelics extracted from plants have been used in religious, spiritual, and mystic practices for millennia. In 1957, Dr. Hofmann identified and synthesized the prodrug psilocybin, a substance present in more than 200 species of psychedelic mushrooms ...
Maurizio Coppola   +2 more
doaj   +1 more source

Dephosphorylation of Psilocybin to Psilocin by Alkaline Phosphatase

open access: yesExperimental Biology and Medicine, 1961
SummaryIncubation of psilocybin with purified intestinal phosphatase resulted in liberation of psilocin and inorganic phosphate.
A, HORITA, L J, WEBER
openaire   +2 more sources

Direct Analysis of Psilocin and Muscimol in Urine Samples Using Single Drop Microextraction Technique In-Line with Capillary Electrophoresis

open access: yesMolecules, 2020
The fully automated system of single drop microextraction coupled with capillary electrophoresis (SDME-CE) was developed for in-line preconcentration and determination of muscimol (MUS) and psilocin (PSC) from urine samples.
Anna Poliwoda   +2 more
doaj   +1 more source

Half a gram – a thousand lives [PDF]

open access: yes, 2008
The article presents information on the latest drug policy change in the Russian Criminal Code: a decrease of the drug threshold amounts for which possession can lead to a criminal liability.
Lev Levinson
core   +2 more sources

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