Results 31 to 40 of about 2,121 (171)

An Overview on the Taxonomy, Phylogenetics and Ecology of the Psychedelic Genera Psilocybe, Panaeolus, Pluteus and Gymnopilus

Frontiers in Forests and Global Change, 2022
Psilocybin and psilocin, two psychoactive components found in “magic mushrooms,” have therapeutic potential in a number of mental health disorders without the addictiveness and overdose risks found in other mind-altering drugs, such as cocaine ...
Dominique Strauss, Soumya Ghosh, Zurika Murray, Marieka Gryzenhout   +3 more
doaj   +1 more source

Classic psychedelics do not affect T cell and monocyte immune responses

Frontiers in Psychiatry, 2023
IntroductionClassic psychedelics have been shown to exert therapeutic potential for the treatment of various psychiatric disorders, neuropsychiatric diseases, and neuronal damage.
Deborah Rudin, Deborah Rudin, Alexander Areesanan, Matthias E. Liechti, Matthias E. Liechti, Carsten Gründemann   +5 more
doaj   +1 more source

The Psychedelic Psilocin Suppresses Activity of Central Amygdala Corticotropin-Releasing Factor Receptor 1 Neurons and Decreases Ethanol Drinking in Female Mice. [PDF]

J Neurosci
Magee SN, Sereno AC, Echeveste-Sanchez M, Shannon EG, Mohsin A, Mott SE, Faccidomo SP, Hodge CW, Herman MA.   +8 more
europepmc   +2 more sources

A Review of Synthetic Access to Therapeutic Compounds Extracted from Psilocybe

Pharmaceuticals, 2022
Psychedelics are used for various pathologies of the central nervous system and are currently the subject of much research, some of which relates to the compounds contained in various Psilocybe-type hallucinogenic mushrooms.
Raphaël Serreau, Ammar Amirouche, Amine Benyamina, Sabine Berteina-Raboin   +3 more
doaj   +1 more source

In vivo validation of psilacetin as a prodrug yielding modestly lower peripheral psilocin exposure than psilocybin

Frontiers in Psychiatry
IntroductionThe use of the psychedelic compound psilocybin in conjunction with psychotherapy has shown promising results in the treatment of psychiatric disorders, though the underlying mechanisms supporting these effects remain unclear.
Nathan T. Jones, Laura Wagner, Molly C. Pellitteri Hahn, Cameron O. Scarlett, Cody J. Wenthur   +4 more
doaj   +1 more source

Therapeutic use of psilocybin: Practical considerations for dosing and administration

Frontiers in Psychiatry, 2022
The interest in psilocybin as a therapeutic approach has grown exponentially in recent years. Despite increasing access, there remains a lack of practical guidance on the topic for health care professionals.
Caroline A. MacCallum, Lindsay A. Lo, Carly A. Pistawka, Jagpaul Kaur Deol   +3 more
doaj   +1 more source

Mixed toxin profiles in two new and one known species of Inocybe (Inocybaceae) from northern China [PDF]

MycoKeys
Mushroom poisoning has become a serious food safety issue in China. Poisoning incidents caused by species of Inocybaceae have been continuously reported from tropical to temperate regions of China in recent years.
Jia-Qi Liang, Xin Chen, Tie-Zhi Liu, Yi-Zhe Zhang, Cheng-Ye Sun, Zhong-Feng Li, Jia-Ju Zhong, Hai-Jiao Li, Yu-Guang Fan, Fei Xu   +9 more
doaj   +3 more sources

Psilocin, A Psychedelic Drug, Exerts Anticonvulsant Effects Against PTZ‐ and MES‐Induced Seizures in Mice via 5‐HT1A and CB1 Receptors: Involvement of Nitrergic, Opioidergic, and Kynurenine Pathways

Pharmacology Research & Perspectives
Epilepsy, a chronic neurological disorder affecting around 65 million people globally, is characterized by recurrent, unprovoked epileptic seizures. Psilocin, the active metabolite of psilocybin, a well‐known psychedelic compound, has recently gained ...
Mohammad Balabandian, Mohammad Amin Manavi, Ali Lesani, Razieh Mohammad Jafari, Hamed Shafaroodi, Navid Heidari, Javad Mirnajafi‐Zadeh, Alireza Foroumadi, Arya Afrooghe, Ahmad Reza Dehpour   +9 more
doaj   +1 more source

Intermolecular Carbon–Carbon Naphthalene Coupling Involves a Radical Mechanism Driven by Cytochrome P450 in Alternaria alternata

Angewandte Chemie International Edition, EarlyView.
1,8‐DHN is an important intermediate to form complex aromatic ring systems. Phenol‐coupling reactions are important for the dimerization of two molecules. Here, we show that a fungal cytochrome P450 enzyme catalyzes specific C─C bonds. ABSTRACT Dihydroxynaphthalene (DHN) derivatives are precursors of biologically important molecules, including melanin ...
Jia Gao, Leyao Chen, Karin Steffen, Henrik Schweder, Birgit Schreckenberger, Shu‐Ming Li, Ben Auxier, Antonis Rokas, Reinhard Fischer   +8 more
wiley   +1 more source

A five-step synthesis of psilocin from indole-3-carbaldehyde [PDF]

, 1998
A novel preparative method of psilocin was established in only five steps from indole-3-carbaldehyde in 50% overall yield.金沢大学大学院自然科学研究科生理活性物質科学金沢大学薬学部journal ...
26419, Tamura, Mayumi, Somei, Masanori, 24593, 80135087, 26786, 20110546, Yamada, Fumio   +7 more
core   +2 more sources