Acta Crystallographica Section E: Crystallographic CommunicationsThe title compound, C12H16N2O, is a hydroxy-substituted monoamine alkaloid, and the primary metabolite of the naturally occurring psychedelic compound psilocybin.
Matthias Zeller +2 more
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The Psychedelic Psilocin Suppresses Activity of Central Amygdala Corticotropin-Releasing Factor Receptor 1 Neurons and Decreases Ethanol Drinking in Female Mice. [PDF]
J NeurosciAlcohol use disorder (AUD) is a highly prevalent disorder with limited therapeutic options. The central amygdala (CeA) is a critical brain region as dysregulation within the CeA and the corticotropin-releasing factor (CRF) system are associated with AUD ...
Magee SN +8 more
europepmc +2 more sources
Psilocin Identified in a DUID Investigation [PDF]
Journal of Analytical Toxicology, 2006 Psilocin was identified in a urine specimen collected during a routine driving under the influence of drugs investigation, the first for this laboratory. The subject did not exhibit any response to an automobile crash, indicating the he may have been unaware of the severity of the situation or his immediate surroundings.
Nicholas B, Tiscione, Mattheu I, Miller
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Psilocin, A Psychedelic Drug, Exerts Anticonvulsant Effects Against PTZ- and MES-Induced Seizures in Mice via 5-HT1A and CB1 Receptors: Involvement of Nitrergic, Opioidergic, and Kynurenine Pathways. [PDF]
Pharmacol Res PerspectEpilepsy, a chronic neurological disorder affecting around 65 million people globally, is characterized by recurrent, unprovoked epileptic seizures. Psilocin, the active metabolite of psilocybin, a well‐known psychedelic compound, has recently gained ...
Balabandian M +9 more
europepmc +2 more sources
The Theoretical Description for Psilocin Electrochemical Determination over Cobalt Oxyhydroxide
, 2023 The possibility of psilocin electrochemical determination over cobalt (III) oxyhydroxide-modified anode is evaluated from the mathematical point of view.
Petro Yagodynets +20 more
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Psilocin fosters neuroplasticity in iPSC-derived human cortical neurons. [PDF]
ElifePsilocybin is studied as innovative medication in anxiety, substance abuse and treatment-resistant depression. Animal studies show that psychedelics promote neuronal plasticity by strengthening synaptic responses and protein synthesis. However, the exact
Schmidt M +9 more
europepmc +2 more sources
Novel qNMR Method to Quantify Psilocybin and Psilocin in Psychedelic Mushrooms. [PDF]
ACS OmegaPsychedelic mushrooms of the Psilocybe genus contain the psychoactive tryptamines psilocybin and psilocin, compounds currently under clinical investigation for the treatment of depression and other psychiatric conditions.
Rodríguez L +5 more
europepmc +2 more sources
Analysis of Psilocin, Bufotenine and LSD in Hair [PDF]
Journal of Analytical Toxicology, 2014 A method for the simultaneous extraction of the hallucinogens psilocin, bufotenine, lysergic acid diethylamide (LSD) as well as iso-LSD, nor-LSD and O-H-LSD from hair with hydrochloride acid and methanol is presented. Clean-up of the hair extracts is performed with solid phase extraction using a mixed-mode cation exchanger.
Rafaela, Martin +4 more
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Psilocin acutely alters sleep-wake architecture and cortical brain activity in laboratory mice
, 2022 Serotonergic psychedelic drugs, such as psilocin (4-hydroxy-N,N-dimethyltryptamine), profoundly alter the quality of consciousness through mechanisms which are incompletely understood.
Bréant, Benjamin J +6 more
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Dephosphorylation of Psilocybin to Psilocin by Alkaline Phosphatase
Experimental Biology and Medicine, 1961 SummaryIncubation of psilocybin with purified intestinal phosphatase resulted in liberation of psilocin and inorganic phosphate.
A, HORITA, L J, WEBER
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