Results 1 to 10 of about 19,791 (256)
DNA-psoralen: single-molecule experiments and first principles calculations [PDF]
Applied Physics Letters Volume: 95 Issue: 25 Article Number:
253703, 2009, 2010 The authors measure the persistence and contour lengths of DNA-psoralen complexes, as a function of psoralen concentration, for intercalated and crosslinked complexes. In both cases, the persistence length monotonically increases until a certain critical
Alexandre, S. S. +4 more
core +2 more sources
Herbal Formula Yi-Fei-Jie-Du-Tang Regulates Epithelial-Mesenchymal Transition and Vasculogenic Mimicry in Lung Cancer via HIF1A-Mediated Ferroptosis. [PDF]
Adv Biol (Weinh)Yi‐Fei‐Jie‐Du‐Tang (YFJDT), a traditional Chinese medicine, has shown potential in lung cancer treatment by targeting key pathways. This study explores the mechanisms of YFJDT using bioinformatics, xenograft models, and A549 cells, demonstrating that YFJDT downregulates HIF1A, promotes ferroptosis, and inhibits epithelial‐mesenchymal transition (EMT ...
Wang S +6 more
europepmc +2 more sources
Development and functional evaluation of a psoralen-conjugated nucleoside mimic for triplex-forming oligonucleotides. [PDF]
Commun ChemPsoralen-conjugated triplex-forming oligonucleotides (Ps-TFOs) have been employed for the photodynamic regulation of gene expression by the photo-cross-linking of psoralen with the target DNA.
Mikame Y +4 more
europepmc +2 more sources
Effects of Narrowband Ultraviolet B Therapy on the Skin Barrier in a Murine Model of Dry Skin. [PDF]
Photodermatol Photoimmunol PhotomedPhotodermatology, Photoimmunology &Photomedicine, Volume 41, Issue 3, May 2025.
Toyama S +4 more
europepmc +2 more sources
Biotransformation of furanocoumarins by Cunninghamella elegans [PDF]
Bulletin of Faculty of Pharmacy Cairo University, 2015 Biotransformation of Furanocoumarins; psoralen (1), bergapten (2), xanthotoxin (3) and imperatorin (4) was explored by Cunninghamella elegans NRRL 1392, revealing the metabolism of psoralen (1) and bergapten (2) into bergaptol (5), while xanthotoxin (3 ...
Abou-El-seoud, Kamillia A. +2 more
core +4 more sources
The effects of CYP2B6 inactivators on the metabolism of ciprofol. [PDF]
PLoS OneCiprofol is a novel short-acting intravenous anaesthetic developed in China that is mainly metabolized by cytochrome P450 2B6 (CYP2B6) and uridine diphosphate glucuronosyltransferase 1A9 (UGT1A9).
Lu M +6 more
europepmc +2 more sources
Cells, 2022 Non-alcoholic fatty liver disease (NAFLD) held a high global prevalence in recent decades. Hepatic lipid deposition is the major characteristic of NAFLD. We aim to explore the mechanisms of psoralen on lipid deposition in NAFLD.
Yuhao Wang +10 more
doaj +1 more source
Therapeutic effect of psoralen on muscle atrophy induced by tumor necrosis factor-α [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): To observe and determine the effect and mechanism of psoralen on tumor necrosis factor-α (TNF-α)-induced muscle atrophy.Materials and Methods: Three sets of C2C12 cells, including blank control, TNF-α (10 or 20 ng/ml) treatment and a TNF-α (
Xin-Feng Lin +7 more
doaj +1 more source
Scientific Reports, 2021 Psoralen is one of the most effective ingredients extracted from the Chinese herb, Psoralea corylifolia L. Studies have found that psoralen has anti-inflammatory and estrogen-like effects; however, little research has been conducted to elucidate the ...
Huxiao Li +6 more
doaj +1 more source
BMC Pharmacology and Toxicology, 2020 Background Diabetic nephropathy (DN) causes the vast proportion of excess mortality for patients with diabetes. Novel therapeutic approaches slowing down its incidence is still lacking. Psoralen is the major active ingredient of Psoralea corylifolia Linn.
Yongtao Lin +5 more
doaj +1 more source