Results 11 to 20 of about 18,448 (248)

A Review of the Pharmacological Properties of Psoralen [PDF]

Frontiers in Pharmacology, 2020
Psoralen is the principal bioactive component in the dried fruits of Cullen corylifolium (L.) Medik (syn. Psoralea corylifolia L), termed “Buguzhi” in traditional Chinese medicine (TCM).
Yali Ren, Xiaominting Song, Lu Tan, Chuanjie Guo, Miao Wang, Hui Liu, Zhixing Cao, Yuzhi Li, Cheng Peng   +8 more
doaj   +5 more sources

Psoralen inhibits malignant proliferation and induces apoptosis through triggering endoplasmic reticulum stress in human SMMC7721 hepatoma cells

Biological Research, 2019
Background Psoralen is a coumarin-like and coumarin-related benzofuran glycoside, which is a commonly used traditional Chinese medicine to treat patients with kidney and spleen-yang deficiency symptom.
Xiaomin Wang, Peike Peng, Zhiqiang Pan, Zhaoqin Fang, Wenli Lu, Xiaomei Liu   +5 more
doaj   +2 more sources

Psoralen Induced Liver Injury by Attenuating Liver Regenerative Capability

Frontiers in Pharmacology, 2018
Psoralen is a major component of the common traditional Chinese medicine Fructus Psoraleae (FP). In this study, we focused on psoralen to explore FP-induced hepatotoxicity and the underlying mechanisms.
Wang Zhou, Xi Chen, Guolin Zhao, Dengqiu Xu, Zhenzhou Jiang, Zhenzhou Jiang, Zhenzhou Jiang, Luyong Zhang, Luyong Zhang, Luyong Zhang, Luyong Zhang, Tao Wang, Tao Wang   +12 more
doaj   +2 more sources

New Application of Psoralen and Angelicin on Periodontitis With Anti-bacterial, Anti-inflammatory, and Osteogenesis Effects

Frontiers in Cellular and Infection Microbiology, 2018
Psoralen and angelicin are two effective compounds isolated from psoraleae, a traditional Chinese medicine. They have a wide range of applications for bone disease treatment and immune modulation. In this study, we explored their new applications for the
Xiaotian Li, Xiaotian Li, Chunbo Yu, Chunbo Yu, Yi Hu, Yi Hu, Xinyi Xia, Xinyi Xia, Yue Liao, Yue Liao, Jing Zhang, Jing Zhang, Huiwen Chen, Huiwen Chen, Weili Lu, Weili Lu, Wei Zhou, Wei Zhou, Zhongchen Song, Zhongchen Song   +19 more
doaj   +2 more sources

Psoralen induced cell cycle arrest by modulating Wnt/β-catenin pathway in breast cancer cells

Scientific Reports, 2018
Psoralen could inhibit the proliferation of human breast cancer cells, however, the molecular mechanism was unclear. We evaluated the anti-proliferative effects of psoralen by MTT, plate colony formation assay and cell cycle analysis in MCF-7 and MDA-MB ...
Xiaohong Wang, Chengfeng Xu, Yitong Hua, Kai Cheng, Yingzhe Zhang, Jian Liu, Yong Han, Song Liu, Guoqiang Zhang, Shujian Xu, Zhenlin Yang   +10 more
doaj   +2 more sources

Psoralens. [PDF]

BMJ, 1969
R. M. B. MacKenna
  +6 more sources

Long-Term Exposure of Psoralen and Isopsoralen Induced Hepatotoxicity and Serum Metabolites Profiles Changes in Female Rats

Metabolites, 2019
:Pre-clinical safety evaluation of traditional medicines is imperative because of the universality of drug-induced adverse reactions. Psoralen and isopsoralen are the major active molecules and quality-control components of a traditional herbal medicine ...
Yingli Yu, Pengli Wang, Ruili Yu, Jiaxi Lu, Miaomiao Jiang, Kun Zhou   +5 more
doaj   +2 more sources

Effects of psoralen on the pharmacokinetics of anastrozole in rats

Pharmaceutical Biology, 2018
Context: Psoralen and anastrozole are always used together for breast cancer patients in Chinese clinics. Objective: This study investigates the effects of psoralen on the pharmacokinetics of anastrozole in rats and its potential mechanism. Materials and
Yuzhu Zhang, Jingjing Wu, Yue Zhou, Yulian Yin, Hongfeng Chen   +4 more
doaj   +2 more sources

Psoralen and Bakuchiol Ameliorate M-CSF Plus RANKL-Induced Osteoclast Differentiation and Bone Resorption Via Inhibition of AKT and AP-1 Pathways in Vitro

Cellular Physiology and Biochemistry, 2018
Background/Aims: Psoralen and bakuchiol are the main active compounds found in the traditional Chinese medicine Psoralea corylifolia L., and have been used to treat osteoporosis.
Lijuan Chai, Kun Zhou, Shaoxia Wang, Han Zhang, Na Fan, Jie Li, Xiaofeng Tan, Limin Hu, Xiang Fan   +8 more
doaj   +2 more sources

Psoralen inhibits the proliferation and promotes apoptosis through endoplasmic reticulum stress in human osteosarcoma cells.

Folia Histochemica et Cytobiologica, 2022
INTRODUCTION . Psoralen is a main active component of Psoralea corylifolia Linn. (Leguminosae). Psoralen has been reported to show antitumor effects and activity to accelerate osteoblastic proliferation.
Shubo Li, Hongqin Tu
semanticscholar   +1 more source