Results 11 to 20 of about 19,791 (256)

Psoralens. [PDF]

BMJ, 1969
R. M. B. MacKenna
  +6 more sources

A Review of the Pharmacological Properties of Psoralen [PDF]

Frontiers in Pharmacology, 2020
Psoralen is the principal bioactive component in the dried fruits of Cullen corylifolium (L.) Medik (syn. Psoralea corylifolia L), termed “Buguzhi” in traditional Chinese medicine (TCM).
Yali Ren, Xiaominting Song, Lu Tan, Chuanjie Guo, Miao Wang, Hui Liu, Zhixing Cao, Yuzhi Li, Cheng Peng   +8 more
doaj   +4 more sources

A theoretical insight into the photophysics of psoralen [PDF]

The Journal of Chemical Physics, 2006
Psoralen photophysics has been studied on quantum chemistry grounds using the multiconfigurational second-order perturbation method CASPT2. Absorption and emission spectra of the system have been rationalized by computing the energies and properties of ...
Bonnett R., Cadet J., Juan José Serrano-Pérez, Luis Serrano-Andrés, Manuela Merchán, McHale J. L., Meffert H., Musajo L., Rouhi A. M., Serrano-Andrés L.   +9 more
core   +5 more sources

Part IV: Basic Considerations of the Psoralens: The Chemistry of the Psoralens11From the Division of Dermatology, University of Oregon Medical School, Portland, Oregon. [PDF]

, 1959
Fowlks, W.L.
core   +2 more sources

Psoralen Promotes Proliferation, Migration, and Invasion of Human Extravillous Trophoblast Derived HTR-8/Svneo Cells in vitro by NF-κB Pathway

Frontiers in Pharmacology, 2022
Recurrent spontaneous abortion (RSA) is a kind of pathological pregnancy, and abnormal function of trophoblast cells may be related to a variety of pregnancy complications including RSA.
Dan Qi, Jingyuan Lu, Ziyi Fu, Shanshan Lv, Lili Hou   +4 more
doaj   +1 more source

Cytochrome P450 CYP1B1 interacts with 8-methoxypsoralen (8-MOP) and influences psoralen-Ultraviolet A (PUVA) sensitivity [PDF]

, 2013
Background: There are unpredictable inter-individual differences in sensitivity to psoralen-UVA (PUVA) photochemotherapy, used to treat skin diseases including psoriasis.
Deeni, Yusuf Y., Ibbotson, Sally H., Smith, Gillian, Wolf, C. Roland, Woods, Julie A.   +4 more
core   +9 more sources

X-Ray Psoralen Activated Cancer Therapy (X-PACT). [PDF]

PLoS ONE, 2016
This work investigates X-PACT (X-ray Psoralen Activated Cancer Therapy): a new approach for the treatment of solid cancer. X-PACT utilizes psoralen, a potent anti-cancer therapeutic with current application to proliferative disease and extracorporeal ...
Mark Oldham, Paul Yoon, Zak Fathi, Wayne F Beyer, Justus Adamson, Leihua Liu, David Alcorta, Wenle Xia, Takuya Osada, Congxiao Liu, Xiao Y Yang, Rebecca D Dodd, James E Herndon, Boyu Meng, David G Kirsch, H Kim Lyerly, Mark W Dewhirst, Peter Fecci, Harold Walder, Neil L Spector   +19 more
doaj   +1 more source

Psoralen alleviates radiation-induced bone injury by rescuing skeletal stem cell stemness through AKT-mediated upregulation of GSK-3β and NRF2

Stem Cell Research & Therapy, 2022
Background Repairing radiation-induced bone injuries remains a significant challenge in the clinic, and few effective medicines are currently available.
Bo-Feng Yin, Zhi-Ling Li, Zi-Qiao Yan, Zheng Guo, Jia-Wu Liang, Qian Wang, Zhi-Dong Zhao, Pei-Lin Li, Rui-Cong Hao, Meng-Yue Han, Xiao-Tong Li, Ning Mao, Li Ding, Da-Fu Chen, Yue Gao, Heng Zhu   +15 more
doaj   +1 more source

Psoralen Induces Developmental Toxicity in Zebrafish Embryos/Larvae Through Oxidative Stress, Apoptosis, and Energy Metabolism Disorder

Frontiers in Pharmacology, 2018
Psoralen toxicity is an issue of wide concern. However, an assay for psoralen-induced developmental toxicity has not been reported to date. Moreover, the underlying mechanism of psoralen-induced developmental toxicity is unclear.
Qing Xia, Lingying Wei, Yun Zhang, Haotian Kong, Yongping Shi, Yongping Shi, Xue Wang, Xiqiang Chen, Liwen Han, Kechun Liu   +9 more
doaj   +1 more source

Psoralen and ultraviolet A light treatment directly affects phosphatidylinositol 3-kinase signal transduction by altering plasma membrane packing [PDF]

, 2016
Psoralen and ultraviolet A light (PUNTA) are used to kill pathogens in blood products and as a treatment of aberrant cell proliferation in dermatitis, cutaneous T-cell lymphoma, and graft versus-host disease.
Compernolle, Veerle, Devloo, Rosalie, Feys, Hendrik, Sandra, Koen, t'Kindt, Ruben, Van Aelst, Britt, Vandekerckhove, Philippe, Zachée, Pierre   +7 more
core   +2 more sources