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A Elbow and forearm with erythematous, well-demarcated, pink plaques with mild micaceous scale in a 42-year-old White woman. B Elbow and forearm with violaceous, well-demarcated plaques with micaceous scale and hyperpigmented patches around the active plaques in a 58-year-old Black man.
Candrice R, Heath, Richard P, Usatine
openaire +4 more sources
Psoriasis is a chronic, immune-mediated disorder with cutaneous and systemic manifestations and substantial negative effects on patient quality of life. Psoriasis has a strong, albeit polygenic, genetic basis. Whereas approximately half of the accountable genetic effect of psoriasis maps to the major histocompatibility complex, >70 other loci have been
Sabat, Robert+2 more
+10 more sources
Psoriasis is a common relapsing and remitting immune-mediated inflammatory disease that affects the skin and joints. This review focuses on current immunogenetic concepts, key cellular players, and axes of cytokines that are thought to contribute to disease pathogenesis.
Ulrich Mrowietz, Jörg Christoph Prinz
+9 more sources
BackgroundOver 1.1 billion people smoke worldwide. The alkaloid nicotine is a prominent and addictive component of tobacco. In addition to tumors and cardiovascular disorders, tobacco consumption is associated with a variety of chronic-inflammatory ...
Theresa-Charlotte Brembach+6 more
doaj +1 more source
Hair and Scalp Disease Detection using Machine Learning and Image Processing [PDF]
Almost 80 million Americans suffer from hair loss due to aging, stress, medication, or genetic makeup. Hair and scalp-related diseases often go unnoticed in the beginning. Sometimes, a patient cannot differentiate between hair loss and regular hair fall.
arxiv +1 more source
Generalized pustular psoriasis (GPP), the most grievous variant of psoriasis, is featured by dysregulated systemic inflammatory response. The cellular and molecular basis of GPP is poorly understood.
Ning Yu+7 more
doaj +1 more source
Die Psoriasis ist eine Hautkrankheit, die sich nach außen hin durch scharf begrenzte, gerötete Plaques infolge entzündlicher Hautinfiltration und einer fest haftenden, silbrig weißen Schuppung infolge epidermaler Hyperproliferation und Parakeratose auszeichnet.
Navarini, Alexander A., Trüeb, Ralph M.
+8 more sources
Introduction Although the efficacy of monotherapy with biologics for psoriasis is well established, many patients fail to achieve complete plaque clearance from their initial biologic treatment alone.
Jerry Bagel+3 more
doaj +1 more source