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A Elbow and forearm with erythematous, well-demarcated, pink plaques with mild micaceous scale in a 42-year-old White woman. B Elbow and forearm with violaceous, well-demarcated plaques with micaceous scale and hyperpigmented patches around the active plaques in a 58-year-old Black man.
Candrice R, Heath, Richard P, Usatine
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Psoriasis is a chronic, immune-mediated disorder with cutaneous and systemic manifestations and substantial negative effects on patient quality of life. Psoriasis has a strong, albeit polygenic, genetic basis. Whereas approximately half of the accountable genetic effect of psoriasis maps to the major histocompatibility complex, >70 other loci have been
Sabat, Robert+2 more
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Psoriasis is a common relapsing and remitting immune-mediated inflammatory disease that affects the skin and joints. This review focuses on current immunogenetic concepts, key cellular players, and axes of cytokines that are thought to contribute to disease pathogenesis.
Ulrich Mrowietz, Jörg Christoph Prinz
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BackgroundOver 1.1 billion people smoke worldwide. The alkaloid nicotine is a prominent and addictive component of tobacco. In addition to tumors and cardiovascular disorders, tobacco consumption is associated with a variety of chronic-inflammatory ...
Theresa-Charlotte Brembach+6 more
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Generalized pustular psoriasis (GPP), the most grievous variant of psoriasis, is featured by dysregulated systemic inflammatory response. The cellular and molecular basis of GPP is poorly understood.
Ning Yu+7 more
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Die Psoriasis ist eine Hautkrankheit, die sich nach außen hin durch scharf begrenzte, gerötete Plaques infolge entzündlicher Hautinfiltration und einer fest haftenden, silbrig weißen Schuppung infolge epidermaler Hyperproliferation und Parakeratose auszeichnet.
Navarini, Alexander A., Trüeb, Ralph M.
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Introduction Although the efficacy of monotherapy with biologics for psoriasis is well established, many patients fail to achieve complete plaque clearance from their initial biologic treatment alone.
Jerry Bagel+3 more
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Association of Psoriasis With Anxiety and Depression: A Case–Control Study in Chinese Patients
Background: Patients with psoriasis are prone to suffer from anxiety and depression during their lifetime. This study aimed to investigate the association of psoriasis with anxiety and depression in Chinese patients.Methods: A case-control study in ...
Danrong Jing+22 more
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