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Positive associations between triglyceride-glucose (TyG) and TyG-body mass index (TyG-BMI) with cardiovascular disease in patients with psoriasis: cross-sectional results from the SPEECH [PDF]
Frontiers in ImmunologyBackgroundPatients with psoriasis have an increased risk of developing cardiovascular disease(CVD), yet reliable potential markers for cardiovascular risk assessment remain insufficient.
Ying Li +15 more
doaj +2 more sources
Impact of temperature trend-defined seasonality on psoriasis treatment outcomes: a multicenter longitudinal study [PDF]
Frontiers in ImmunologyBackgroundPsoriasis severity and symptoms are widely known to vary seasonally. However, evidence on the impact of seasonality on treatment outcomes is limited, with vague season definitions.
Xinyi Song, Qin Yang, Yuye Wang, Ning Yu
doaj +2 more sources
Cutis, 2021 A Elbow and forearm with erythematous, well-demarcated, pink plaques with mild micaceous scale in a 42-year-old White woman. B Elbow and forearm with violaceous, well-demarcated plaques with micaceous scale and hyperpigmented patches around the active plaques in a 58-year-old Black man.
Candrice R, Heath, Richard P, Usatine
openaire +6 more sources
Der Hautarzt, 2016 Psoriasis is a chronic, immune-mediated disorder with cutaneous and systemic manifestations and substantial negative effects on patient quality of life. Psoriasis has a strong, albeit polygenic, genetic basis. Whereas approximately half of the accountable genetic effect of psoriasis maps to the major histocompatibility complex, >70 other loci have been
Sabat, Robert +2 more
+10 more sources
Annual Review of Pathology: Mechanisms of Disease, 2012 Psoriasis is a common relapsing and remitting immune-mediated inflammatory disease that affects the skin and joints. This review focuses on current immunogenetic concepts, key cellular players, and axes of cytokines that are thought to contribute to disease pathogenesis.
Ulrich Mrowietz, Jörg Christoph Prinz
+9 more sources
Association of Psoriasis With Anxiety and Depression: A Case–Control Study in Chinese Patients
Frontiers in Medicine, 2021 Background: Patients with psoriasis are prone to suffer from anxiety and depression during their lifetime. This study aimed to investigate the association of psoriasis with anxiety and depression in Chinese patients.Methods: A case-control study in ...
Danrong Jing +22 more
doaj +1 more source
Frontiers in Immunology, 2021 Generalized pustular psoriasis (GPP), the most grievous variant of psoriasis, is featured by dysregulated systemic inflammatory response. The cellular and molecular basis of GPP is poorly understood.
Ning Yu +7 more
doaj +1 more source
JAK3 as an emerging target for topical treatment of inflammatory skin diseases [PDF]
, 2016 The recent interest and elucidation of the JAK/STAT signaling pathway created new targets for the treatment of inflammatory skin diseases (ISDs). JAK inhibitors in oral and topical formulations have shown beneficial results in psoriasis and alopecia ...
Alves de Medeiros, Ana +5 more
core +8 more sources