Results 11 to 20 of about 116,439 (236)
Nature Reviews Disease Primers, 2016 Psoriasis is a chronic, immune-mediated disorder with cutaneous and systemic manifestations and substantial negative effects on patient quality of life. Psoriasis has a strong, albeit polygenic, genetic basis. Whereas approximately half of the accountable genetic effect of psoriasis maps to the major histocompatibility complex, >70 other loci have been
Greb, Jacqueline E. +8 more
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Cold Spring Harbor Perspectives in Medicine, 2014 Psoriasis is a common chronic inflammatory skin disease with a spectrum of clinical phenotypes and results from the interplay of genetic, environmental, and immunological factors. Four decades of clinical and basic research on psoriasis have elucidated many of the pathogenic mechanisms underlying disease and paved the way to effective targeted ...
Paola, Di Meglio +2 more
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Cutis, 2021 A Elbow and forearm with erythematous, well-demarcated, pink plaques with mild micaceous scale in a 42-year-old White woman. B Elbow and forearm with violaceous, well-demarcated plaques with micaceous scale and hyperpigmented patches around the active plaques in a 58-year-old Black man.
Candrice R, Heath, Richard P, Usatine
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Canadian Medical Association Journal, 2012 Psoriasis is a common relapsing and remitting immune-mediated inflammatory disease that affects the skin and joints. This review focuses on current immunogenetic concepts, key cellular players, and axes of cytokines that are thought to contribute to disease pathogenesis.
Anatoli, Freiman, Benjamin, Barankin
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Journal of the Royal College of Physicians of Edinburgh, 2013 Psoriasis is a chronic, immune-mediated inflammatory skin disease affecting 1.3–2.2% of the UK population.1 Most commonly, psoriasis is characterised by well-demarcated, red plaques with adherent scale with a predilection for the scalp and extensor surfaces of the limbs.
L, Burfield, A D, Burden
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Frontiers in Medicine, 2021 Background: Although there have been many epidemiological studies, research focusing on psoriasis' health burden on a global scale is still lacking.
Chen Peng +15 more
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Therapeutische Umschau, 2010 Die Psoriasis ist eine Hautkrankheit, die sich nach außen hin durch scharf begrenzte, gerötete Plaques infolge entzündlicher Hautinfiltration und einer fest haftenden, silbrig weißen Schuppung infolge epidermaler Hyperproliferation und Parakeratose auszeichnet.
Navarini, Alexander A., Trüeb, Ralph M.
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Guidelines for the Diagnosis and Treatment of Psoriasis in China: 2019 Concise Edition#
International Journal of Dermatology and Venerology, 2020 . Psoriasis is an immune-mediated chronic, recurrent, systemic inflammatory disease induced by the combination of hereditary and environmental factors.
Committee of Psoriasis, Dermatology Branch, Chinese Medical Association
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Frontiers in Immunology, 2022 Psoriasis is a worldwide chronic inflammatory skin disease. The treatment of disease is usually designed according to its severity. In this research, RNA-seq was performed on 37 patients with psoriasis treated with guselkumab before and after treatment ...
Jiajing Lu +15 more
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Trials, 2019 Introduction Psoriasis vulgaris is a common skin disease characterized by persistent localized erythematous scaly plaques, typically on the elbows, knees, and scalp. It is an immune-abnormal disease that progresses slowly over a long period with frequent
Jingwen Deng +7 more
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