Results 21 to 30 of about 293,751 (369)
Metabolomics in psoriatic disease: pilot study reveals metabolite differences in psoriasis and psoriatic arthritis. [PDF]
ImportanceWhile "omics" studies have advanced our understanding of inflammatory skin diseases, metabolomics is mostly an unexplored field in dermatology.ObjectiveWe sought to elucidate the pathogenesis of psoriatic diseases by determining the differences
Armstrong, April W+6 more
core +2 more sources
Psoriasis is a worldwide chronic inflammatory skin disease. The treatment of disease is usually designed according to its severity. In this research, RNA-seq was performed on 37 patients with psoriasis treated with guselkumab before and after treatment ...
Jiajing Lu+15 more
doaj +1 more source
Multi-omics integration reveals molecular networks and regulators of psoriasis. [PDF]
BackgroundPsoriasis is a complex multi-factorial disease, involving both genetic susceptibilities and environmental triggers. Genome-wide association studies (GWAS) and epigenome-wide association studies (EWAS) have been carried out to identify genetic ...
Arneson, Douglas+5 more
core +3 more sources
Using micro- and macro-level network metrics unveils top communicative gene modules in psoriasis [PDF]
Background: Psoriasis is a multifactorial chronic inflammatory disorder of the skin with significant morbidity, characterized by hyper proliferation of the epidermis. Even though psoriasis etiology is not fully understood, it is believed to be multifactorial with numerous key components.
arxiv +1 more source
Evaluation of the cutaneous microbiome in psoriasis [PDF]
Psoriasis, a highly prevalent disease of humans of unknown cause, is a chronic inflammatory disorder primarily involving skin, with distinctive clinical characteristics.
Alexander Alekseyenko+5 more
core +2 more sources
A new combination product containing betamethasone dipropionate and calcipotriol (DovobetĀ® ointment) has been proven very effective and well tolerated in patients with psoriasis vulgaris.
G.A. Vena+37 more
doaj +1 more source
Plasma total antioxidant capacity and peroxidation biomarkers in psoriasis [PDF]
Systemic biomarkers of oxidative stress can be relevant for assessment of psoriasis severity, for prediction of the outcome of therapy and of the development of comorbidities.
Cavaliere, Arturo+2 more
core +2 more sources
Dysregulated Peripheral Invariant Natural Killer T Cells in Plaque Psoriasis Patients
Background: Psoriasis is a common immune-mediated skin disease that involves T-cell-mediated immunity. Invariant natural killer T (iNKT) cells are a unique lymphocyte subpopulation that share properties and express surface markers of both NK cells and T ...
Yifan Hu+25 more
doaj +1 more source
Nonadherence to psoriasis medication as an outcome of limited coping resources and conflicting goals: findings from a qualitative interview study with people with psoriasis [PDF]
Background Medication nonadherence is known to limit the effectiveness of available therapies; however, little is known specifically about medication adherence in people with psoriasis.
Baker+48 more
core +2 more sources
Introduction Psoriasis vulgaris is a common skin disease characterized by persistent localized erythematous scaly plaques, typically on the elbows, knees, and scalp. It is an immune-abnormal disease that progresses slowly over a long period with frequent
Jingwen Deng+7 more
doaj +1 more source