Results 51 to 60 of about 322,632 (326)

Long-term efficacy and safety of guselkumab in Chinese patients with moderate-to-severe plaque psoriasis

Frontiers in Medicine, 2023
BackgroundRandomized controlled trials indicated guselkumab, the first anti-interleukin-23 monoclonal antibody, is efficacious in plaque psoriasis. However, guselkumab's performance in real life is scarcely examined, especially in China.ObjectivesThis ...
Jianfeng Zheng, Jianfeng Zheng, Wenjuan Chen, Wenjuan Chen, Xuemei Yi, Xuemei Yi, Ning Yu, Ning Yu, Yangfeng Ding, Yangfeng Ding, Yunlu Gao, Yunlu Gao   +11 more
doaj   +1 more source

Psoriasis

New England Journal of Medicine, 2005
Psoriasis is an immune-mediated, genetic disease manifesting in the skin or joints or both. A diverse team of clinicians with a range of expertise is often needed to treat the disease. Psoriasis provides many challenges including high prevalence, chronicity, disfiguration, disability, and associated comorbidity.
Boehncke, Wolf-Henning, Schoen, Michael Peter   +1 more
openaire   +8 more sources

Cardiometabolic Comorbidities in Patients With Psoriasis: Focusing on Risk, Biological Therapy, and Pathogenesis

Frontiers in Pharmacology, 2021
Psoriasis is a chronic inflammatory disease characterized by erythematous scaly plaques, accompanied by systemic damage that leads to the development of multiple comorbidities.
Jiangluyi Cai, Jiangluyi Cai, Lian Cui, Lian Cui, Yu Wang, Yu Wang, Ying Li, Ying Li, Xilin Zhang, Xilin Zhang, Yuling Shi, Yuling Shi   +11 more
doaj   +1 more source

Clinical consequences of antibody formation, serum concentrations, and HLA-Cw6 status in psoriasis patients on Ustekinumab [PDF]

, 2019
Background: Ustekinumab for the treatment of psoriasis is currently administered in a standard dosing regimen. However, some patients tend to benefit from alternative dosing regimens, a step toward personalized medicine.
Busard, Celine, I, Costanzo, Antonio, De Keyser, Eline, Hutten, Barbara A., Lambert, Jo, Lanssens, Sven, Meuleman, Lieve, Spuls, Phyllis, I, van den Reek, Juul M., Zweegers, Jeffrey   +9 more
core   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source

"I don't want to manage it, I want to get rid of it" : a narrative analysis of living with chronic plaque psoriasis, and an investigation into vitamin D as a treatment : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Nutritional Science at Massey University, Albany, New Zealand [PDF]

, 2017
As a chronic skin disease, plaque psoriasis can cause significant psychosocial, emotional and physical burden. Psoriasis sufferers perceive others as lacking understanding around what it is like to live with this condition, and there has been little ...
Ingram, Michelle Anne
core  

Disseminated eruptive giant mollusca contagiosa in an adult psoriasis patient during efalizumab therapy [PDF]

, 2008
Molluscum contagiosum is a common viral skin infection in children with atopic diathesis and not rare in HIV patients. We report a 45-year-old psoriasis patient who developed eruptive mollusca contagiosa during an antipsoriatic treatment with efalizumab.
Alexander Vasilevic Kuznetsov, Jö, Lim KS, Michael Flaig, Papp KA, Peter Weisenseel, Vozmediano JM, Wachi K   +7 more
core   +1 more source

Novel 3D‐Printed Biophotonic Scaffold Displaying Luminescence under Near‐Infrared Light for Photopharmacological Activation and Biological Signaling Compound Release

Advanced Healthcare Materials, EarlyView.
Despite significant efforts in developing novel biomaterials to regenerate tissue, only a few of them have successfully reached clinical use. It has become clear that the next generation of biomaterials must be multifunctional. Smart biomaterials can respond to environmental or external stimuli, interact in a spatial‐temporal manner, and trigger ...
Sonya Ghanavati, Ekin Opar, Virginia Alessandra Gobbo, Carlo Matera, Fabio Riefolo, Rossella Castagna, Julien Colombelli, Andrew Draganski, Joshua Baggott, Mika Lastusaari, Pau Gorostiza, Laeticia Petit, Jonathan Massera   +12 more
wiley   +1 more source

Metabolomics in psoriatic disease: pilot study reveals metabolite differences in psoriasis and psoriatic arthritis. [PDF]

, 2014
ImportanceWhile "omics" studies have advanced our understanding of inflammatory skin diseases, metabolomics is mostly an unexplored field in dermatology.ObjectiveWe sought to elucidate the pathogenesis of psoriatic diseases by determining the differences
Armstrong, April W, Azizi, Baktazh, Dhillon, Jaskaran, Fiehn, Oliver, Grapov, Dmitry, Johnson, Mary Ann, Wu, Julie   +6 more
core   +2 more sources

Hydrocolloid‐Based Multiwavelength Stretchable QD‐OLED Patch for Simultaneous Neonatal Jaundice and Dermatitis Treatment with Biosignal Monitoring

Advanced Healthcare Materials, EarlyView.
Comparison of therapeutic and diagnostic applications of a surface‐emitting light source with multiwavelength emission characteristics. Abstract Conventional light‐emitting‐diode‐based light sources suffer from rigidity, localized heating, and poor adaptability to skin deformation, limiting their use in skin‐attached medical devices.
In Ho Kim, Young Woo Kim, Jae‐Young Jeong, Ye Ji Shin, Chaeyeong Lee, Jae Gyun Choi, Oh Kwan Kwon, Kyoung Hwa Kim, Sang Jik Kwon, Eou‐Sik Cho, Yongmin Jeon   +10 more
wiley   +1 more source