, 2020 Autism Spectrum Disorder (ASD) is a a group of neurodevelopmental disorders. It shows high level of heterogeneity genetically and clinically. There are inadequacies in social communication and interaction, limited interests, stereotypic motor behavior and speech failure in ASD.
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Applying next-generation sequencing to enable marker-assisted breeding for adaptive traits in common bean (Phaseolus vulgaris L.). [PDF]
This research establishes molecular breeding capability for adapting common bean (Phaseolus vulgaris L.) to UK growing conditions. A high-resolution linkage map was constructed for a bi-parental recombinant inbred population (large brown x small white ...
Tock, Andrew J.
core
In Silico Systems Biology Approach for Prioritization of Candidate Genes Linked to Lipid Metabolism in the Context of Cardiovascular Disease Susceptibility in a Serbian Cohort. [PDF]
Curr Issues Mol BiolDrljača T +3 more
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Journal of Inflammation ResearchJiale He, Kesong Li, Zilin Guo, Xinyao Zhou, Xiaopo Tang Department of Rheumatology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, People’s Republic of ChinaCorrespondence: Xinyao Zhou, Email xyz_1102@126.com Xiaopo ...
He J, Li K, Guo Z, Zhou X, Tang X
doaj
Phosphatase targeting in Luminal B breast cancer: PGP.
Breast cancer can be positive for expression of a hormone receptor (ESR/PGR/AR) or a growth factor receptor (ERBB2). Disease recurrence following disease remission (relapse), resistance to endocrine therapy or otherwise inadequate long-term control of disease are challenges that limit effectiveness of existing drugs that treat luminal A and luminal B ...
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LIS1 mediated Schwann cell reprogramming enhances perineural invasion by activating the serine/NMDAR/AKT signaling pathway in head and neck squamous carcinoma. [PDF]
Cancer Cell IntLiu J +7 more
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Therapeutic targeting in breast cancer for the treatment of lung metastasis: SHB.
Metastasis is the major cause of death from cancer and metastasis to the lung in breast cancer is difficult to treat and heterogeneous in nature, complicating its management (1-5). We recently utilized whole transcriptome technologies to define the full complement of differentially expressed kinases and phosphatases in HER2+ breast cancer: in the ...
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Development of the membranous labyrinth in E9.5 to E14.5 C57BL/6N mouse embryos. Stage specific metric and descriptive reference data and their use for identifying malformations. [PDF]
Front Cell Dev BiolMaurer-Gesek B, Geyer SH, Weninger WJ.
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Catalytic site targeting in HER2+ breast cancer for the treatment of CNS metastasis: PSPH.
Up to 50% of patients with HER2+ subtype breast cancer develop metastasis to the central nervous system, most commonly the brain, demanding rapid therapeutic approaches to limit spread of the HER2+ primary tumor to distant sites (1-3). We recently described the existence of a group of genes that reside proximal to ERBB2 (the gene that encodes the ...
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Metabolic remodeling and immune evasion in glioblastoma: a focus on serine and lipid networks. [PDF]
Front OncolJiang D, Wang C, Zhao Y, Li Y.
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