We study breast cancer in humans as a model for understanding cancer as a system in its entirety and as a life cycle, including cell of origin, transformation, subtype selection, biology and ecology of the primary tumor, the tumor microenvironment, tumor immunology and surveillance, dissemination via the circulating tumor cell, metastasis to the lymph ...
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The "serine code" of metabolic reprogramming: multidimensional roles of the serine synthesis pathway in tumors and novel breakthroughs for targeted therapy. [PDF]
Su P, Yang Y, Zheng H.
europepmc +1 more source
Recent progress in serine metabolism reprogramming in tumors and strategies for serine deprivation. [PDF]
Liu H, Liu Y.
europepmc +1 more source
Multi-Omics Mendelian Randomization Identifies Therapeutic Targets for Sjögren's Disease with Clinical and Bayesian Validation. [PDF]
He J, Li K, Guo Z, Zhou X, Tang X.
europepmc +1 more source
IGF2BP2-driven serine metabolism promotes the progression of thyroid carcinoma via m<sup>6</sup>A-PHGDH. [PDF]
Zhang Y, Xiao Z, Dong X, Wang Q.
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Aishwarya Raj +6 more
doaj +1 more source
Serine metabolism reprogramming in cancer: a multi-tiered regulatory framework. [PDF]
Yuan Y, Wang K, Jin Y, Han T.
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SRSF7 serves as a potential therapeutic target in acute myeloid leukemia. [PDF]
Shang D +6 more
europepmc +1 more source
Gut Dysbiosis Serine-Glycine Metabolism and Glioblastoma: Exploring Therapeutic Opportunities. [PDF]
Mangano M +6 more
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VimR is a conserved master transcription regulator controlling virulence and metabolism in Pseudomonas. [PDF]
Chen F +9 more
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