Results 141 to 150 of about 499,109 (301)

New Psychoactive Substances

, 2017
The final report of the NPS-t study presents the results of a survey among over 3.000 NPS users from 6 countries. Results include patterns of use, user profiles, procurement, market dynamics, and prevention. This report highlights the variety in types of NPS users and across countries.
Benschop, A., Bujalski, M., Dabrowska, K., Demetrovics, Z., Egger, D., Felinczi, K., Henriques, S., Kalo, Z., Kamphausen, G., Korf, D.J., Nabben, T., Silva, J.P., van Hout, M.C., Werse, B., Wells, J., Wieczorek, L., Wouters, M.   +16 more
  +6 more sources

Editorial: Prescribing psychotropics: Misuse, abuse, dependence, withdrawal and addiction, Volume II

Frontiers in Psychiatry, 2022
Stefania Chiappini, Stefania Chiappini, Fabrizio Schifano, Giovanni Martinotti, Giovanni Martinotti   +4 more
doaj   +1 more source

The challenge of new psychoactive substances. A report from the Global SMART Programme. [PDF]

, 2013
1. INTRODUCTION p.1 1.1 Emergence of new psychoactive substances 1.2 Definition and categories of new psychoactive substances 2. MAIN NEW PSYCHOACTIVE SUBSTANCES ENCOUNTERED IN ILLICIT MARKETS AND THEIR EFFECTS p.3 2.1 Synthetic cannabinoids 2 ...

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Assessment and management of dyspareunia in peri‐ and postmenopausal women: A phenotype‐based gynecologic approach

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Dyspareunia in peri‐ and postmenopausal women is common, clinically consequential, and often undertreated in gynecologic practice. Although genitourinary syndrome of menopause (GSM) is a frequent contributor, intercourse‐related pain may also reflect vestibular, pelvic floor, dermatologic, inflammatory, treatment‐related, and psychosocial ...
Marek Broul, Marcel Vančo, Jaroslava Banýrová, Aneta Hujová   +3 more
wiley   +1 more source

Neurobiology and toxicity of new psychoactive substances from hallucinogens class [PDF]

, 2019
Main focus of this thesis are the novel synthetic psychoactive substances from hallucinogens class. The first part expands the phenomenon of hallucinogens and describes its general mechanisms.
Zmátlo, Vít
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Bidirectional Pathological Axis Between Alzheimer's Disease and Circadian Rhythm Disturbance: Mechanisms and Therapeutic Strategies

iNew Medicine, EarlyView.
This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin, Xianfeng Yu, Yayu Wang, Xiaohan Song, Yuehua Wang, Zhixin Wang, Wei Miao, Xudong Yang, Jiajia Zhu, Xiaoqun Zhu, Maria‐Trinidad Herrero   +10 more
wiley   +1 more source

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos, Matheus Cavalcanti de Barros, Cleidiane Silva Vieira de Souza, Ryan Cristian da Silva, Luana Cassandra Breitenbach Barroso Coelho, Maria Tereza dos Santos Correia, Fernanda das Chagas Ângelo Mendes Tenório, Alisson Macário de Oliveira, Thiago Henrique Napoleão, Robson Raion de Vasconcelos Alves, Patrícia Maria Guedes Paiva   +10 more
wiley   +1 more source

Potential Neuroendocrine Disruption by Benzodiazepines and Its Impact on Male Fertility

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neuroactive substances have emerged as potent endocrine disruptors affecting male reproductive health through central and peripheral mechanisms. Among these, benzodiazepines, which are widely used for the management of anxiety, insomnia, epilepsy, and neuromuscular disorders, are known as GABA A (gamma‐aminobutyric acid type A) receptor ...
Ana Clara Melo Andrade de Rodrigues, Julia Gonçalves Rodrigues, Marcos de Lucca Moreira Gomes, Fernanda Carolina Ribeiro Dias   +3 more
wiley   +1 more source

The Psychometric Properties and Clinical Usefulness of the Difficulties in Emotion Regulation Scale in Forensic Settings

Journal of Clinical Psychology, EarlyView.
ABSTRACT Objective The Difficulties in Emotion Regulation Scale (DERS) is a widely used measure of emotion dysregulation across clinical contexts. However, its psychometric properties and clinical utility have not been thoroughly examined in forensic populations.
Adam Meddeb, Märta Wallinius, Johan Berlin, Natalie Laporte, Malin Hildebrand Karlén, Claudia Mazzeschi, Elisa Delvecchio, Patrizia Velotti, Carlo Garofalo   +8 more
wiley   +1 more source

The Dangers of Psychoactive Substances

, 2023
Substance addictions,which have origins in historical times to the present, directly affect theeconomy and security of countries as well as public health.
Kuloğlu Genç, Merve, Mercan, Selda
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