Results 241 to 250 of about 499,109 (301)

Psychoactive substances: novel molecular insights and therapeutic potential for Alzheimer's disease. [PDF]

Transl Neurodegener
Fu C, Li X, Liu X, Zheng Y, Ma X, Zhang B, Chen S, Hu L, Su S, Wang X, Sun J, Yin Q, Wang Y, Fu X, Bao Y, Xue Y, Xin T, Lu L, Zou G.   +18 more
europepmc   +1 more source

Proof‐of‐concept trial of PP‐01 for mitigating cannabis withdrawal syndrome in participants with cannabis use disorder

The American Journal on Addictions, EarlyView.
Abstract Background and Objectives Cannabis withdrawal symptoms can be severe and protracted, significantly impeding the ability to abstain from cannabis use, resulting in failed quit attempts and relapse. This clinical trial evaluated safety and efficacy of PP‐01, a novel dual‑mechanism of action, investigational agent, for mitigating cannabis ...
Ashley F. Slagle, Jay Constantine, Harvey Kushner, Shelli Graham, Ginger Constantine   +4 more
wiley   +1 more source

Emergency Department presentations due to new psychoactive substances (NPS) and other illicit drugs: a clinical and toxicological study on recreational drug toxicity in Italy. [PDF]

Int J Legal Med
Giorgetti A, Venturi A, Barone R, Rossi F, Pirani F, Pascali JP, Giostra F, Pelletti G.   +7 more
europepmc   +1 more source

Sleep Disorders in Klinefelter Syndrome and Other Sex Chromosome Aneuploidies: A Narrative Review

Andrology, EarlyView.
ABSTRACT Background Sex chromosome aneuploidies (SCAs) are among the most frequent types of chromosomal aneuploidies and include Klinefelter syndrome (47,XXY and higher‐grade variants), 47,XYY syndrome, Turner syndrome (45,X), and trisomy X (47,XXX).
Roberto Paparella, Fabiola Panvino, Ida Pucarelli, Luigi Tarani   +3 more
wiley   +1 more source

Contribution of Addictovigilance data to assess adverse-events linked to psychoactive substances in children and adolescents. [PDF]

Br J Clin Pharmacol
Peyrière H, Batisse A, Sam-Laï NF, Daveluy A, Fournier-Choma C, Deheul S, Chevalier C, Lacroix C, Gibaja V, Aquizerate A, Pain S, Jouanjus E, Picot MC, Nogue E.   +13 more
europepmc   +1 more source

The Need for a Global Registry for Charting the Natural History of Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Although Klinefelter Syndrome (KS) represents the most common sex chromosome aneuploidy, several gaps in knowledge persist regarding optimal management of individuals with this condition. Individuals with KS can have a diverse phenotype including endocrine, neurodevelopmental, and cardiovascular manifestations.
Malika Alimussina, Joseph McElvaney, Corinna Grasemann, Jillian Bryce, Lise Aksglaede, Claudia Boettcher, Lexi Breen, Francesco Carlomagno, Sabine Hannema, Andrea M. Isidori, Inas Mazen, Anna Nordenstrom, S. Faisal Ahmed, Angela K. Lucas‐Herald   +13 more
wiley   +1 more source

Deadly confusion of novel psychoactive substances: fatal outcome of ADB-BUTINACA mislabeled as 3',4'-methylenedioxy-α-pyrrolidinohexiophenone. [PDF]

Forensic Toxicol
Zschiesche A, Theofel N, Braukmüller S, Ehrlich E, Jasyk M, Methling M, Tsokos M, Scholtis S, Huppertz LM, Auwärter V.   +9 more
europepmc   +1 more source

Cross‐Sectional Study of the PREValence of Erectile DysfunctIon in the Arteriopathic Population (PREVEDI)

Andrology, EarlyView.
ABSTRACT Background Although the association between erectile dysfunction (ED) and cardiovascular disease is well established, its prevalence in patients with atherosclerosis remains poorly defined. Objectives To evaluate ED prevalence, severity, and associated risk factors (RFs) in patients with atherosclerotic disease.
Luca Farchioni, Andrea Ferri, Nicola Leone, Mattia Migliari, Luigi Alberto Maria Bartolotti, Daniele Santi, Giorgia Spaggiari, Roberto Silingardi, Stefano Gennai   +8 more
wiley   +1 more source

Distribution patterns of narcotic drugs, psychotropic substances, and new psychoactive substances among reported drug users in china (2014-2026): A systematic review and Meta-Analysis. [PDF]

Addict Behav Rep
Wang Q, Qin Z, Qin L, Xing X, Wang Z, Cui H, Zhang J, Xing Y, Chen J, Zhao M, Luo W, Zhu H, Jia Z.   +12 more
europepmc   +1 more source