Results 241 to 250 of about 77,099 (293)

Toxicokinetic modelling of the synthetic cannabinoid 5F‐MDMB‐P7AICA and its main metabolite in pigs following pulmonary administration

British Journal of Clinical Pharmacology, EarlyView.
Aims Since their emergence on the drug market, synthetic cannabinoids (SC) are still gaining increasing importance in forensic toxicology. The representatives of the so‐called new psychoactive substances have in common that they have not undergone preclinical safety studies. Hence, knowledge on toxicokinetic (TK) data is sparse.
Adrian A. Doerr, Christiane Dings, Omar Zaher, Frederike Nordmeier, Nadja Walle, Matthias W. Laschke, Michael D. Menger, Peter H. Schmidt, Markus R. Meyer, Thorsten Lehr, Nadine Schaefer   +10 more
wiley   +1 more source

Optimization of Parallel Artificial Liquid Membrane Extraction for the Determination of Over 50 Psychoactive Substances in Oral Fluid Through UHPLC-MS/MS. [PDF]

Drug Test Anal
Croce M, Montesano C, Bracaglia I, Bartolini F, Mascini M, Compagnone D, Sergi M.   +6 more
europepmc   +1 more source

Safety pharmacology of acute mescaline administration in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims Psychedelics, including mescaline, may serve as novel treatments for depression and anxiety. However, data is scarce on the safety of mescaline. Methods The present pooled analysis included two double‐blind, randomized, placebo‐controlled studies with a total of 48 participants and 96 mescaline administrations. Single oral‐dose administrations (n =
Aaron Klaiber, Mélusine Humbert‐Droz, Laura Ley, Yasmin Schmid, Matthias E. Liechti   +4 more
wiley   +1 more source

Using sleep to enhance exposure treatment for anxious children: A pilot study

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives: Exposure therapy is a well‐established treatment for anxiety disorders in children; however, many young people do not fully respond to treatment. Advances in strategies to enhance extinction learning from exposure therapy are urgently needed.
Ella L. Oar, Ronald M. Rapee, Cassie H. Lavell, Allison G. Harvey, Thomas H. Ollendick   +4 more
wiley   +1 more source

Qualitative and quantitative in silico toxicity profiling of "angel dust": phencyclidine (PCP) analogues as new psychoactive substances (3-HO-PCP, 3-MeO-PCP, 4-MeO-PCP, 3-HO-PCE, 3-MeO-PCE, 4-MeO-PCE). [PDF]

Arch Toxicol
Noga M, Jurowski K.
europepmc   +1 more source

Anxiety, Depression, Schizophrenia, and Bipolar Disorder in Eosinophilic Esophagitis Patients: A Global Federated Cohort Analysis of Bidirectional Risks

Allergy, EarlyView.
Hui‐Chin Chang, Meng‐Che Wu, Torsten Zuberbier, Shuo‐Yan Gau   +3 more
wiley   +1 more source

Health risk perception and behavioral decision-making among online-dating MSM in Shandong, China: perspectives on HIV and new psychoactive substances. [PDF]

BMC Public Health
Chen Y, Yu H, Zhu X, Li L, Wang L, Zhuoma Y, Zhang N, Wang G, Ma W, Liao M.   +9 more
europepmc   +1 more source

Motives for New Psychoactive Substances Consumption among Young Adults in Uzbekistan: A Qualitative Study Protocol. [PDF]

Consort Psychiatr
Zakhidova G, Pikirenia U, Syunyakov T, Prilutskaya M.   +3 more
europepmc   +1 more source

New Psychoactive Substances Toxicity: A Systematic Review of Acute and Chronic Psychiatric Effects. [PDF]

Int J Mol Sci
Taflaj B, La Maida N, Tittarelli R, Di Trana A, D'Acquarica I.   +4 more
europepmc   +1 more source

Utilizing Caenorhabditis Elegans as a Rapid and Precise Model for Assessing Amphetamine-Type Stimulants: A Novel Approach to Evaluating New Psychoactive Substances Activity and Mechanisms. [PDF]

Adv Sci (Weinh)
Li Y, Li H, Wang H, Wang X.
europepmc   +1 more source