Results 91 to 100 of about 28,032 (195)

Associations of living alone and loneliness with neuropsychiatric symptoms in individuals with mild cognitive impairment: A retrospective cross‐sectional study

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 5, Issue 1, March 2026.
Abstract Aim Living alone and loneliness are recognized risk factors for neuropsychiatric symptoms in older adults. However, the distinct of the objective condition of living alone and subjective loneliness on specific neuropsychiatric symptoms in individuals with mild cognitive impairment (MCI) remains unclear.
Kayo Takeda   +7 more
wiley   +1 more source

Educational delays and psychological burden by disability status among newly graduated medical students in Japan

open access: yes
Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 1, March 2026.
Kana Kiryu   +9 more
wiley   +1 more source

Acute Liver Failure With Transient Liver Steatosis Following Multiple Hits Postoperatively in a Patient With Limb‐Girdle Muscular Dystrophy: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Transient liver steatosis is rarely described. A fast development of liver steatosis leading to acute liver failure (ALF) is, to our knowledge, rarely observed. It is so far observed and published in acute fatty liver of pregnancy, and in a few cases of ALF. However, it is observed in elective surgery for pancreaticoduodenectomy and some cases
Anders Benjamin Kildal   +7 more
wiley   +1 more source

The Pathway to Proof‐of‐Concept for BNC210, a Negative Allosteric Modulator of the Alpha‐7 Nicotinic Acetylcholine Receptor (nAChR), for Treatment of Psychiatric Disease

open access: yesClinical Pharmacology in Drug Development, Volume 15, Issue 2, February 2026.
Abstract BNC210 is an investigational small molecule selective negative allosteric modulator of the alpha‐7 nicotinic acetylcholine receptor (α7 nAChR). It is an anxiolytic compound with a novel mechanism of action. In a series of Phase 1 clinical trials in healthy volunteers, psychometric test batteries showed that BNC210 did not cause attention ...
Paul Rolan   +7 more
wiley   +1 more source

Development and Validation of the Brief Inventory of Treatment Expectations in Chronic Pain (BITEC)

open access: yesEuropean Journal of Pain, Volume 30, Issue 2, February 2026.
ABSTRACT Background Expectations shape therapeutic outcomes, yet their systematic assessment remains limited in clinical and research settings. To address this gap, we developed and validated the Brief Instrument for the Assessment of Treatment Expectations in Chronic Pain (BITEC) using Item Response Theory. Methods The study comprised four phases. (I)
Wolnei Caumo   +8 more
wiley   +1 more source

Exogenous Melatonin and Sleep Quality: A Scoping Review of Systematic Reviews

open access: yesThe Journal of Clinical Pharmacology, Volume 66, Issue 2, February 2026.
Abstract Melatonin is increasingly used to treat sleep disturbances, yet its overall efficacy remains unclear due to variability in existing evidence. This scoping review aimed to synthesize systematic reviews with meta‐analyses assessing the effects of exogenously administered melatonin on sleep quality in humans.
Samyuktha Iyer   +3 more
wiley   +1 more source

A Case of Recurrence of Severe Depressive Disorder With Flu—Neuroinflammatory Basis of Depressive Disorder

open access: yesProgress in Neurology and Psychiatry, Volume 30, Issue 1, February 2026.
ABSTRACT This case highlights a relapse of major depressive disorder in an elderly man following a flu‐like illness, with clinical features and laboratory findings supporting a possible inflammatory contribution. It emphasises the relevance of the inflammatory theory of depression, especially in individuals with late‐life depression and recent immune ...
Nauman Malik, Mohamed A. Mohamed
wiley   +1 more source

The Prevalence and Predictors of Self‐Harm Among Young Women With Substance Use Disorder: A Cross‐Sectional Comparative Study

open access: yesProgress in Neurology and Psychiatry, Volume 30, Issue 1, February 2026.
ABSTRACT Self‐harm is a significant public health concern, particularly among young women, and is closely associated with psychiatric comorbidities and risky behaviors. This study aimed to compare the prevalence and contributing factors of self‐harm among young women with and without substance use disorder (SUD).
Lida Jarahi   +2 more
wiley   +1 more source

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