Results 81 to 90 of about 131,822 (267)
Effect of the NFIB rs28379954 T>C polymorphism on CYP2D6‐catalyzed metabolism of solanidine
Clinical and Translational ScienceCytochrome P450 2D6 (CYP2D6) is important for metabolism of 20%–25% of all clinically used drugs. Many known genetic variants contribute to the large interindividual variability in CYP2D6 metabolism, but much is still unexplained.
Robert Løvsletten Smith +7 more
doaj +1 more source
Medicines, 2017 Background: The Ayurvedic medicinal system employs a holistic approach to health, utilising the synergistic properties of organic resources. Research into the Ayurvedic herb Bacopa monnieri (L.) Wettst. (B.monnieri) has reported improvements in cognitive
James D Kean, Luke A Downey, Con Stough
doaj +1 more source
Behavioral Profiles of Genetically Selected Aggressive and Nonaggressive Male Wild House Mice in Two Anxiety Tests [PDF]
, 2000 Artificially selected aggressive (SAL) and non-aggressive (LAL) male house mice were tested in a hexagonal tunnel maze and light–dark preference (LD) box to determine if the bidirectional selection for aggressive behavior leads to a coselection for ...
Hof, Maleen, +6 more
core +2 more sources
Addiction, EarlyView.Abstract Background and aims Lower risk guidelines for safer levels of cannabis use could help to reduce the health burden posed by cannabis use disorder (CUD). We aimed to estimate risk thresholds for CUD based on delta‐9‐tetrahydrocannabinol (THC) consumption using standard THC units (1 unit = 5 mg THC).
Rachel Lees Thorne +9 more
wiley +1 more source
Drug addiction as a physical disease:The role of physical dependence and other chronic drug-induced neurophysiological changes in compulsive drug self-administration [PDF]
, 1998 Physical-dependence-based theories of addiction regard compulsive drug taking as the behavioral manifestation of a desperate need to relieve aversive autonomic withdrawal symptoms.
Lyvers, Michael
core +1 more source
Addiction, EarlyView.Abstract Background and aims Ketamine assisted psychotherapy is a promising new treatment for alcohol use disorder (AUD). The psychoactive effects of repeated intravenous (IV) ketamine infusions in people with AUD and their mechanistic role in treating AUD are largely unknown.
Cassie Bloy +11 more
wiley +1 more source
On 3‐MMC: A Cathinone I Have Come to Know and Love
Anthropology of Consciousness, EarlyView.ABSTRACT This article attempts to complicate the mythology of a compound in a state of becoming. I will trace lightly its origins as a cultural disruptor and how I am implicated in this imperative. Introducing you to 3‐MMC will require multiple modes of storytelling and taking of liberties, drawing on literature reviews, practice‐based research, prose,
Carmen Ostrander
wiley +1 more source
Birth‐Related Experiences and Postpartum Depression: The Protective Role of Self‐Compassion
Birth, EarlyView.Does self‐compassion (SC) moderate the relationship between birth satisfaction, type of birth, and early skin‐to‐skin contact (SSC) in women's PPD symptoms? Methods: 987 women with an infant aged 0–5 months. 62.1% Vaginal delivery. 66.3% SSC contact after delivery.
Helena Moreira, Colin R. Martin
wiley +1 more source
Frontiers in Human Neuroscience, 2017 People with Autism spectrum disorder (ASD) show difficulty in social communication, especially in the rapid assessment of emotion in faces. This study examined the processing of emotional faces in typically developing adults with high and low levels of ...
Svjetlana Vukusic +2 more
doaj +1 more source
Food-induced behavioral sensitization, its cross-sensitization to cocaine and morphine, pharmacological blockade, and effect on food intake [PDF]
, 2006 Repeated administration of abused drugs sensitizes their stimulant effects and results in a drug-paired environment eliciting conditioned activity. We tested whether food induces similar effects.
Le Merrer, Julie, Stephens, David N
core +1 more source