Results 101 to 110 of about 22,716 (169)

PTEN induced putative kinase 1 (PINK1) [PDF]

Science-Business eXchange, 2013
openaire   +1 more source

Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neurons.

The Journal of biological chemistry, 2012
Mutations in the E3 ubiquitin ligase Parkin and the mitochondrial PTEN-induced putative kinase 1 (PINK1) have been identified to cause autosomal recessive forms of familial Parkinson disease, with PINK1 functioning upstream of Parkin in a pathway important for the maintenance of mitochondrial function and morphology.
A. Rakovic, Shurkewitsch K, Seibler P, Grünewald A, Zanon A, Hagenah J, Krainc D, Klein C   +7 more
openaire   +3 more sources

Nitric oxide (NO); PTEN induced putative kinase 1 (PINK1) [PDF]

Science-Business eXchange, 2012
openaire   +1 more source

Xinyin tablets affect mitophagy and cardiomyocyte apoptosis to alleviate chronic heart failure by regulating histone deacetylase 3(HDAC3)-mediated PTEN induced putative kinase 1(PINK1)/Parkin signaling pathway

Journal of Ethnopharmacology
Xinyin tablets, Chinese patent medicine, are composed of Panax ginseng C.A.Mey. (Araliaceae), Ilex pubescens Hook. & Arn. (Aquifoliaceae), Leonurus japonicus Houtt. (Lamiaceae), Plantago asiatica L. (Plantaginaceae), Ophiopogon japonicus (Thunb.) Ker Gawl. (Asparagaceae), Astragalus membranaceus (Fisch.) Bunge, and Draba nemorosa L. (Brassicaceae).
Hanyu Chen, Qianbei Lin, Yanlin Zeng, Pinliang Chen, Pengpeng Guo, Ruoshui Feng, Zhenyu Guo, Jinhua Kang, Qiucen Chen, Xiaoxiong Zhou   +9 more
openaire   +2 more sources

PINK1 functions in mitophagy and mitochondrial homeostasis during mice oocyte maturation

Cell & Bioscience
Background As a serine/threonine kinase, PINK1 (PTEN-induced putative kinase 1) is widely expressed in mammalian tissues and cells, especially in the female reproductive system. However, its role in meiotic oocytes remains obscure.
Shiwei Wang, Xuan Wu, Mengmeng Zhang, Yixiao Zhu, Yajun Guo, Shuang Song, Shenming Zeng   +6 more
doaj   +1 more source

Effects of electroacupuncture on mitophagy mediated by SIRT3/PINK1/Parkin pathway in Parkinson’s disease mice

针刺研究
ObjectiveTo observe the effects of electroacupuncture （EA） at “Fengfu”（GV16）， “Taichong”（LR3）， and “Zusanli”（ST36） on mitophagy mediated by silencing regulatory protein 3 （SIRT3）/ PTEN induced putative kinase 1 （PINK1）/PARK2 gene coding protein （Parkin ...
ZHANG Gui-jun, WANG Yao, LI Jun-ling, MA Jun, WANG Yan-chun   +4 more
doaj  

ATG5 Plays a Role in <i>Toxoplasma gondii</i> Replication and Egress Within Host Cells. [PDF]

Transbound Emerg Dis
Wu F, Wu S, Ding Q, Shi Z, Liang Y, Chen H, Zhang X, Mi J, Chen M, Xu Q.   +9 more
europepmc   +1 more source

PTEN: Regulation, Signalling and Targeting in Cancer. [PDF]

Cancers (Basel)
Kotelevets L, Scott MGH, Chastre E.
europepmc   +1 more source

Mitophagy bridges glucose metabolism, inflammation and neuroprotection in astrocytes. [PDF]

Autophagy
Hakansson H, Howden JH, Kittler JT.
europepmc   +1 more source

PINK1 dysfunction in hepatocellular carcinoma fosters immune evasion and disease progression by promoting neutrophil infiltration. [PDF]

J Immunother Cancer
Gu Z, Yang T, Ni Y, Zhou Y, Qian C, Zhuang N.   +5 more
europepmc   +1 more source