The role of urinary pteridines as disease biomarkers [PDF]
Pteridines, 2017 Pteridines and their derivatives function as intermediates in the metabolism of several vitamins and cofactors, and their relevance to disease has inspired new efforts to study their roles as disease biomarkers.
Casey Burton, Yinfa Ma
exaly +4 more sources
Data on urinary pteridines as a discriminator of atherosclerotic risk in patients with diabetes [PDF]
Data in Brief, 2022 Presented here are the supplemental data of the research article “Urinary pteridines as a discriminator of atherosclerotic risk in patients with diabetes” [1]. These data provide the first information on variables that affect urinary levels of pteridines
Ichiro Wakabayashi
exaly +4 more sources
Urinary pteridines as a discriminator of atherosclerotic risk in patients with diabetes [PDF]
Atherosclerosis Plus, 2021 Background and aims: We have recently proposed urinary pteridine level as a useful biomarker of oxidative stress in a general population. However, the significance of urinary pteridines in patients with diabetes is unknown.
Ichiro Wakabayashi
exaly +4 more sources
Pteridines and Lipid Metabolism [PDF]
Pteridines, 1998 Summary The effect of 9 different pteridines on fatty acid incorporation into phospholipids as well as on cholesterol and phospholipid content was compared in vitro using rat liver homogenate, Krebs-Ringer phosphate buffer containing 0.3 % albumin (pH=7.4), fatty acid mixture and glycerol.
Dietmar Fuchs +5 more
doaj +4 more sources
Biosynthesis of Pteridines in Insects: A Review. [PDF]
InsectsPteridines are important cofactors for many biological functions of all living organisms, and they were first discovered as pigments of insects, mainly in butterfly wings and the eye and body colors of insects. Most of the information on their structures and biosynthesis has been obtained from studies with the model insects Drosophila melanogaster and ...
Ferré J.
europepmc +5 more sources
Establishing pteridine metabolism in a progressive isogenic breast cancer cell model - part II. [PDF]
Metabolomics, 2022 Introduction: Determining the biological significance of pteridines in cancer development and progression remains an important step in understanding the altered levels of urinary pteridines seen in certain cancers.
Rasmussen L +4 more
europepmc +3 more sources
Analysis of the Influence of Changing and Fixed Temperatures on the Growth and Pteridine Content in the Head of Adults Sarcophaga crassipalpis (Diptera: Sarcophagidae). [PDF]
Animals (Basel), 2023 Flesh flies (Diptera: Sarcophagidae) are regarded as significant in medical and veterinary entomology, and their development models can be utilized as considerable markers to ascertain the minimum postmortem interval (PMImin).
Ngando FJ +9 more
europepmc +2 more sources
Novel Aminopyrimidine-2,4-diones, 2-Thiopyrimidine-4-ones, and 6-Arylpteridines as Dual-Target Inhibitors of BRD4/PLK1: Design, Synthesis, Cytotoxicity, and Computational Studies. [PDF]
Pharmaceuticals (Basel), 2023 Structural-based drug design and solvent-free synthesis were combined to obtain three novel series of 5-arylethylidene-aminopyrimidine-2,4-diones (4, 5a–c, 6a,b), 5-arylethylidene-amino-2-thiopyrimidine-4-ones (7,8), and 6-arylpteridines (9,10) as dual ...
El-Kalyoubi S +4 more
europepmc +2 more sources
Pteridines, XCVI. Synthesis and Reactions of 6-(1,2,3-Trihydroxypropyl)pteridines
Pteridines, 1990 Summary Various hydropyrano [3.2-g] pteridines (7, 10, 12, 21 , 33) were oxidized to the corresponding 6-(1,2,3- trihydroxypropyl)pteridine derivatives (8,9, 11, 13,32, 34), which are valuable intermediates for the synthesis of new 6-substituted pteridines (15 - 46).
Rainer Soyka, Wolfgang Pfleiderer
openaire +3 more sources
Prospects for the use of sulfur-containing pteridines in toxic liver damage
Regulatory Mechanisms in BiosystemsThe presented material describes the results of the purposeful search for the novel hepatoprotective agents among synthetic sulfur-containing pteridines. The studied compounds were obtained using previously described synthetic procedures.
N. Lohvinenko +7 more
exaly +3 more sources