Results 21 to 30 of about 8,074 (264)

Homology Cloning of GTP-cydohydrolase I from Fungi and Plants by Reverse-transcription PCR Using a General Set of Degenerate Primers

open access: yesPteridines, 1995
Unconjugated pteridines are present in fungi, algae and plants. However, the functions of pteridines in these organisms are not thoroughly investigated. The biosynthesis follows the same steps as were shown for animals and eubacteria.
Maier Josef   +2 more
doaj   +1 more source

Pteridines in the Control of Pigmentation

open access: yesJournal of Investigative Dermatology, 1997
The influence of UVB irradiation on the metabolic pathway for the production of L-tyrosine from L-phenylalanine in the human epidermis has been examined in 12 healthy volunteers with photo skin types I-VI (Fitzpatrick classification). This metabolic pathway involves the induction of GTP-cyclohydrolase 1 (GTP-CH-1), the rate-limiting enzyme for de novo ...
Christa Körner   +6 more
openaire   +3 more sources

Influence of Neopterin on Ciliary Beat Frequency of Human Nasal Epithelial Cells in vitro

open access: yesPteridines, 2008
Acute infectious diseases of the respiratory tract are regularly associated with increased concentrations of neopterin in serum and/or urine. Most likely, the pteridine compound is not only a marker of an activated cellular immune system but may exert ...
Neher Andreas   +5 more
doaj   +1 more source

Dendritic Molecular Baskets for Selective Binding of Toxic Methotrexate

open access: yesAngewandte Chemie, Volume 137, Issue 9, February 24, 2025.
Dendritic molecular baskets are biocompatible cavitands capable of including toxic methotrexate (MTX) in their aromatic cavity. The binding is chemoselective with the complex forming in competitive cell media. With the unique mode of recognition and modular structure, dendritic baskets are leading candidates for developing effective antidotes against ...
Nitesh Kumar   +8 more
wiley   +2 more sources

Exploring the scope of DBU-promoted amidations of 7-carboxymethyl-pterin [PDF]

open access: yes, 2020
Pteridines are an important heterocycle often used in the development of pharmaceutically relevant compounds, and in the field of supramolecular chemistry.
Bockman, Anna
core   +1 more source

Dilute-and-Shoot-Liquid Chromatography-Quadrupole Time of Flight-Mass Spectrometry for Pteridine Profiling in Human Urine and Its Association with Different Pathologies

open access: yesChemosensors, 2023
Pteridines are a group of compounds synthesised by many living organisms that are involved in the metabolism of many cofactors and vitamins. Their concentration in biological fluids may be altered by various pathologies such as cancer or inflammatory ...
Claudia Giménez-Campillo   +7 more
doaj   +1 more source

First Synthesis of Asperopterin A, an Isoxanthopterin Glycoside from Aspergillus Oryzae [PDF]

open access: yes, 2013
The key precursor, N-2-(N,N -dimethylaminomethylene)-6-hydroxymethyl-8-methyl-3-[2-(4-nitrophenyl)ethyl]-7-xanthopterin (16) was efficiently prepared from 2,5-diamino-6-methylamino-3H-pyrimidin-4-one (5) and ethyl 3-(tert-butyldimethylsilyloxy)-2 ...
Hanaya, Tadashi, Yamamoto, Hiroshi
core   +1 more source

Solvent Effects upon the Electronic Absorption and Fluorescence Spectra of Pteridines and Riboflavin and Their Ground and First Excited Singlet State Dipole Moments

open access: yesPteridines, 1991
The electronic absorption. fluorescence excitation, and fluorescence emission spectra of a series of pteridines (lumazine, xanthopterin, isoxanthopterin, biopterin) and riboflavin (vitamin B2) were measured at room temperature (298 K) in a number of ...
Aaron J.-J.   +8 more
doaj   +1 more source

ESTABLISHING PTERIDINE METABOLISM IN A BREAST CANCER CELL MODEL AND QUANTIFICATION OF SILVER NANOPARTICLE INTERACTIONS WITH YEAST CELLS USING MASS SPECTROMETRY [PDF]

open access: yes, 2022
Recent advances in analytical methods have furthered the quantitative insights that can be gleaned from cellular analyses, with applications in cancer and nanoparticle research. In the first part of the research presented, a recently developed HPLC-MS/MS
Rasmussen, Lindsey Katherine
core   +1 more source

Blocked dihydropteridines as nitric oxide synthase activators [PDF]

open access: yes, 2010
It has been shown that 6-acetyl-7,7-dimethyl-5,6,7,8-tetrahydropteridin-4(3H)-one can act as a competent cofactor for the production of nitric oxide by neuronal nitric oxide synthase (nNOS).
Daff, Simon   +5 more
core  

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