Results 21 to 30 of about 9,956 (243)

Usefulness of serum biopterin as a predictive biomarker for childhood asthma control: A prospective cohort study

Allergology International, 2019
Background: Pteridines are metabolites of tetrahydrobiopterin, which serves as co-enzyme of nitric oxide synthase. We sought to investigate the usefulness of pteridines as biomarkers for childhood asthma control.
Saki Kasuga, Daijiro Kabata, Tomoko Sakaguchi, Satoshi Kudoh, Satsuki Nishigaki, Yusuke Higa, Shiori Fujikawa, Hiroko Fujitani, Ayumi Shintani, Takashi Hamazaki, Haruo Shintaku   +10 more
doaj   +1 more source

Homology Cloning of GTP-cydohydrolase I from Fungi and Plants by Reverse-transcription PCR Using a General Set of Degenerate Primers

Pteridines, 1995
Unconjugated pteridines are present in fungi, algae and plants. However, the functions of pteridines in these organisms are not thoroughly investigated. The biosynthesis follows the same steps as were shown for animals and eubacteria.
Maier Josef, Werner Thomas, Ninnemann Helga   +2 more
doaj   +1 more source

Novel Aminopyrimidine-2,4-diones, 2-Thiopyrimidine-4-ones, and 6-Arylpteridines as Dual-Target Inhibitors of BRD4/PLK1: Design, Synthesis, Cytotoxicity, and Computational Studies

Pharmaceuticals, 2023
Structural-based drug design and solvent-free synthesis were combined to obtain three novel series of 5-arylethylidene-aminopyrimidine-2,4-diones (4, 5a–c, 6a,b), 5-arylethylidene-amino-2-thiopyrimidine-4-ones (7,8), and 6-arylpteridines (9,10) as dual ...
Samar El-Kalyoubi, Samiha A. El-Sebaey, Sherin M. Elfeky, Hanan A. AL-Ghulikah, Mona S. El-Zoghbi   +4 more
doaj   +1 more source

Exploring the scope of DBU-promoted amidations of 7-carboxymethyl-pterin [PDF]

, 2020
Pteridines are an important heterocycle often used in the development of pharmaceutically relevant compounds, and in the field of supramolecular chemistry.
Bockman, Anna
core   +1 more source

Influence of Neopterin on Ciliary Beat Frequency of Human Nasal Epithelial Cells in vitro

Pteridines, 2008
Acute infectious diseases of the respiratory tract are regularly associated with increased concentrations of neopterin in serum and/or urine. Most likely, the pteridine compound is not only a marker of an activated cellular immune system but may exert ...
Neher Andreas, Schobersberger Wolfgang, Augustijns Patrick, Fuchs Dietmar, Wolf-Magele Astrid, Hoffmann Georg   +5 more
doaj   +1 more source

Pteridines and Lipid Metabolism

Pteridines, 1998
The effect of 9 different pteridines on fatty acid incorporation into phospholipids as well as on cholesterol and phospholipid content was compared in vitro using rat liver homogenate, Krebs-Ringer phosphate buffer containing 0.3 % albumin (pH=7.4 ...
Rudzite Vera, Jurika Edite, Baier-Bitterlich Gabriele, Widner Bernhard, Reibnegger Gilbert, Fuchs Dietmar   +5 more
doaj   +1 more source

Dilute-and-Shoot-Liquid Chromatography-Quadrupole Time of Flight-Mass Spectrometry for Pteridine Profiling in Human Urine and Its Association with Different Pathologies

Chemosensors, 2023
Pteridines are a group of compounds synthesised by many living organisms that are involved in the metabolism of many cofactors and vitamins. Their concentration in biological fluids may be altered by various pathologies such as cancer or inflammatory ...
Claudia Giménez-Campillo, Marta Pastor-Belda, Natalia Arroyo-Manzanares, Natalia Campillo, Blanca del Val Oliver, José Zarauz-García, Luis Sáenz, Pilar Viñas   +7 more
doaj   +1 more source

Development of an HPLC-MS method for the determination of natural pteridines in tomato samples

, 2016
In plants, reduced pteridines are folate biosynthesis intermediates, and the presence of these analytes in biofortification processes is considered crucial.
E. Martín-Tornero, D. G. Gómez, I. Durán-Merás, A. Espinosa-Mansilla   +3 more
semanticscholar   +1 more source

Pteridine-2,4-diamine derivatives as radical scavengers and inhibitors of lipoxygenase that can possess anti-inflammatory properties [PDF]

, 2015
BACKGROUND: Reactive oxygen species are associated with inflammation implicated in cancer, atherosclerosis and autoimmune diseases. The complex nature of inflammation and of oxidative stress suggests that dual-target agents may be effective in combating ...
Hadjipavlou-Litina, D, Marson, CM, Patsilinakos, A, Pontiki, E, Tran, TM   +4 more
core   +1 more source

Solvent Effects upon the Electronic Absorption and Fluorescence Spectra of Pteridines and Riboflavin and Their Ground and First Excited Singlet State Dipole Moments

Pteridines, 1991
The electronic absorption. fluorescence excitation, and fluorescence emission spectra of a series of pteridines (lumazine, xanthopterin, isoxanthopterin, biopterin) and riboflavin (vitamin B2) were measured at room temperature (298 K) in a number of ...
Aaron J.-J., Gaye M. D., Párkányi C., Boniface C., Bieze T. W. N, Atik S. S., Raghu Veer K. S., Szentpály L. von, Ghosh R.   +8 more
doaj   +1 more source