Results 161 to 170 of about 2,236 (202)
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In situ detection of pterins by SERS
The Analyst, 2009Surface enhanced Raman scattering (SERS) has been used to detect specific pterin molecules at sub-nanomolar concentrations. SERS is fast becoming a widely used technique for the sensitive and specific detection of multiple analytes. The information-rich and concentration-dependent spectra obtained from SERS make the technique ideally placed for high ...
Stevenson, Ross +8 more
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Inborn Errors of Pterin Metabolism
Annual Review of Nutrition, 1988HY PERPHENY LALANINEMIA DUE TO TETRAHYDROBIOPTERIN DEFICIENCy 188 GTP Cyclohydrolase I Deficiency 188 6-Pyruvoyl Tetrahydropterin Synthase Deficiency 189 Dihydropteridine Reductase Deficiency 191 Other Forms ...
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Inhibition of xanthine oxidase by pterins
Free Radical Research, 1998The effect of a panel of pterins on xanthine oxidase was investigated by measuring formation of urate from xanthine as well as formazan production from nitroblue tetrazolium. The pterin derivatives, depending on their chemical structure, decreased urate as well as formazan generation: 200 microM neopterin and biopterin suppressed urate formation (90 ...
I, Wede +4 more
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Analysis and clinical significance of pterins
Journal of Chromatography B: Biomedical Sciences and Applications, 1988This review briefly describes the biochemistry of pterins, their involvement in pathological processes and the use of pterin measurement in diagnosis and monitoring of disease. Chromatographic and other methods of pterin analysis are detailed with particular emphasis being placed on the need for correct sample collection and handling.
K, Hyland, D W, Howells
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The Synthesis of Fluorine-Containing Pterins
1993The introduction of fluorine into molecules has been well demonstrated to modify the biological properties significantly1. In heterocyclic compounds this effect is clearly demonstrated through the action of 5-fluorouracil and its nucleosides as inhibitors of thymidylate synthetase.
C, Dunn +3 more
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Pterins in patients with rett syndrome
American Journal of Medical Genetics, 1986We have found normal concentrations of neopterin, monapterin, isoxanthopterin, biopterin and pterin in the urine of 10 patients with Rett syndrome, and normal values for total biopterin and neopterin in the blood of 4 subjects. Thus, there is no biochemical evidence of a generalized tetrahydrobiopterin deficiency in this syndrome.
E. Boltshauser +5 more
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Calcium pterin as an antitumor agent
International Journal of Pharmaceutics, 2004A series of in vivo studies are reported that provide evidence for an immunologically mediated mechanism for the antitumor response from a calcium pterin (CaPterin) suspension. Strong antitumor efficacy was demonstrated in fully immunocompetent female C3H/HeN-MTV+ mice (retired breeders) presenting spontaneous mammary gland adenocarcinomas.
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The Biosynthesis of Folate and Pterins and Their Enzymology
2010This work presents a definitive interpretation of the current status of and future trends in natural products-a dynamic field at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids, and ...
Fischer, M, Thöny, B, Leimkühler, S
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Nitric-Oxide-Synthase Inhibitors II — Pterin Antagonists/Anti-Pterins
2000In addition to heme, flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN), nitric oxide synthases (NOS) require tetrahydrobiopterin (H4B). This was first demonstrated for homogenates of stimulated murine macrophages (KWON et al. 1989; TAYEH and MARLETTA 1989). Unlike other enzymes, e.g.
E. R. Werner, H. H. H. W. Schmidt
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