Results 11 to 20 of about 1,595 (174)

Electron Transfer Initiated Reactions Photoinduced by Pterins

Pteridines, 2011
Interest in the photochemistry and photophysics of pterins has increased since the participation of this family of compounds in different photobiological processes has been suggested or demonstrated in recent decades.
Carolina Lorente, María Laura Dántola, Andrés H Thomas   +2 more
exaly   +2 more sources

Segawa Syndrome, a Dramatic Response to Dopamine [PDF]

Case Reports in Neurological Medicine
Segawa syndrome usually manifests as dystonia, disturbance of gait with fatigue, and may be confused with spasticity. Also known as dopamine-responsive dystonia (DRD), it should be considered in any child who presents with paroxysmal or progressive ...
Omkar Dhungel, Amit Shrestha, Pawan Sharma, Nidesh Sapkota, Raju Paudel   +4 more
doaj   +2 more sources

Insights into Molecular Structure of Pterins Suitable for Biomedical Applications [PDF]

International Journal of Molecular Sciences, 2022
Andrey A Buglak, Yuliya L Vechtomova
exaly   +2 more sources

Consensus Guideline for the Diagnosis and Treatment of Tyrosine Hydroxylase (TH) Deficiency. [PDF]

J Inherit Metab Dis
ABSTRACT Tyrosine hydroxylase (TH) catalyses the rate‐limiting step in dopamine biosynthesis. Autosomal recessive tyrosine hydroxylase deficiency (THD) leads to clinical phenotypes reflecting the deficiency of dopamine, norepinephrine, or epinephrine in the central nervous system (CNS), presenting along a continuous spectrum from mild to severe forms ...
Bondarenko MS, Kuseyri Hübschmann O, Kulhánek J, Pons R, Pearson TS, Jeltsch K, Badnjarevic I, Wassenberg T, Horvath G, Stevanovic G, Kurian MA, Cortès-Saladelafont E, Roubertie A, Leuzzi V, Bertoldi M, Mastrangelo M, Assmann B, THD Guidelines Working Group, Garcia-Cazorla A, Opladen T.   +19 more
europepmc   +2 more sources

Pterin-based pigmentation in animals [PDF]

Biology Letters, 2021
Pterins are one of the major sources of bright coloration in animals. They are produced endogenously, participate in vital physiological processes and serve a variety of signalling functions. Despite their ubiquity in nature, pterin-based pigmentation has received little attention when compared to other major pigment classes.
Pedro Andrade, Miguel Carneiro
openaire   +2 more sources

The urinary biopterin in autism spectrum disorder

Pteridines, 2021
The aim of the study was to determine whether biopterin is present in significantly lower quantities in urine samples of patients with autism spectrum disorder (ASD) compared to healthy individuals.
Waligóra Aleksandra, Damasiewicz-Bodzek Aleksandra, Gorczyca Piotr, Waligóra Sławomir, Tyrpień-Golder Krystyna   +4 more
doaj   +1 more source

No QTcF Prolongation with Sepiapterin: Results From a Thorough QT Study in Healthy Subjects at Therapeutic and Supratherapeutic Doses. [PDF]

J Clin Pharmacol
Abstract Sepiapterin and its major metabolite 6R‐L‐erythro‐5,6,7,8‐tetrahydrobiopterin (BH4) bind to distinct variants of phenylalanine hydroxylase (PAH), which converts excess phenylalanine to tyrosine, thereby stabilizing, enhancing, and prolonging PAH activity.
Gao L, Xue H, Darpo B, Ingalls K, Kaushik D, Smith N, Kong R, Golden L.   +7 more
europepmc   +2 more sources

Comparative routes to 7-carboxymethyl-pterin: A useful medicinal chemistry building block

Pteridines, 2022
Pterins, such as folate and biopterin, and their derivatives hold significant importance given their biological relevance, as well as the numerous pterin-based inhibitors developed for targeting various biological targets. For this reason, pterins can be
Bennett Zachary, Grumbles Kassidy, Pruet Jeffrey   +2 more
doaj   +1 more source

Modulation of Free Radical Formation by Pterin Derivatives

Pteridines, 2004
All classes of pterins, fully reduced tetrahydropterins, aromatic pterins and dihydropterins have been investigated upon their effects on radical mediated reactions.
Karl Oettl, Greilberger Joachim, Reibnegger Gilbert   +2 more
doaj   +1 more source

Cerebrospinal Fluid Pterins, Pterin-Dependent Neurotransmitters, and Mortality in Pediatric Cerebral Malaria

The Journal of Infectious Diseases, 2021
Abstract Background Cerebral malaria (CM) pathogenesis remains incompletely understood. Having shown low systemic levels of tetrahydrobiopterin (BH4), an enzymatic cofactor for neurotransmitter synthesis, we hypothesized that BH4 and BH4-dependent neurotransmitters would likewise be low in ...
Matthew P Rubach, Jackson P Mukemba, Salvatore M Florence, Bert K Lopansri, Keith Hyland, Ryan A Simmons, Charles Langelier, Sara Nakielny, Joseph L DeRisi, Tsin W Yeo, Nicholas M Anstey, J Brice Weinberg, Esther D Mwaikambo, Donald L Granger   +13 more
openaire   +5 more sources