Results 21 to 30 of about 4,302 (241)
Publisher Summary This chapter describes the bacterial pterin deaminase. In the standard assay, the mixture contains 0.05 ml of pterin carboxylic acid, 0.8 ml of phosphate buffer, and 0.02 to 0.15 ml of enzyme in a final volume of 1.0 ml. Incubation is carried out at 23° in a 1-ml Beckman quartz cuvette with a light path of 1.00 cm. Reaction is begun
Bruce Levenberg, Osamu Hayaishi
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A contribution to the chemistry of pterins [PDF]
The experiments in this paper have been chiefly concerned with a derivative from pterins, the wing pigments of pierid butterflies. These pigments have become prominent of recent years, partly on account of the prolonged efforts (1925-41) of continental workers to determine their nature.
Frederick Gowland Hopkins
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Abstract Qualitative and quantitative analyses for pterins (derivatives of 2-amino-4-hydroxypteridine) in human urine were carried out by an improved procedure which involved the use of two new weak ion exchangers, ECTEOLA-Sephadex and phospho-Sephadex.
Tetsuo Shiota, Takeshi Fukushima
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Direct coordination of pterin to Fe II enables neurotransmitter biosynthesis in the pterin-dependent hydroxylases [PDF]
Significance The mononuclear pterin-dependent nonheme iron enzymes catalyze the rate-limiting step in neurotransmitter biosynthesis and are essential in maintaining proper brain function. These enzymes utilize molecular oxygen, a redox active pterin cofactor, and a ferrous active site to generate an Fe IV -
Shyam R. Iyer+13 more
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Exploring the scope of DBU-promoted amidations of 7-carboxymethyl-pterin [PDF]
Pteridines are an important heterocycle often used in the development of pharmaceutically relevant compounds, and in the field of supramolecular chemistry.
Bockman, Anna
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Photocarcinogenesis of the skin: Current status and future trends. [PDF]
Abstract Solar radiation is essential for life on Earth but is also a major contributor to skin carcinogenesis. Solar radiation, particularly ultraviolet (UV) B (280–320 nm) and UVA (320–400 nm), induces photocarcinogenesis via various pathways. UV light can directly cause DNA damage, resulting in genetic mutations if not repaired correctly.
Yang TT, Lan CE.
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Mapping an atlas of tissue-specific drosophila melanogaster metabolomes by high resolution mass spectrometry [PDF]
Metabolomics can provide exciting insights into organismal function, but most work on simple models has focussed on the whole organism metabolome, so missing the contributions of individual tissues.
A Kamleh+47 more
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Modulation of Free Radical Formation by Pterin Derivatives
All classes of pterins, fully reduced tetrahydropterins, aromatic pterins and dihydropterins have been investigated upon their effects on radical mediated reactions.
Karl Oettl+2 more
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Comparative routes to 7-carboxymethyl-pterin: A useful medicinal chemistry building block
Pterins, such as folate and biopterin, and their derivatives hold significant importance given their biological relevance, as well as the numerous pterin-based inhibitors developed for targeting various biological targets. For this reason, pterins can be
Bennett Zachary+2 more
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Pterin determination in cerebrospinal fluid: state of the art
The analysis of pterins in the cerebrospinal fluid (CSF) is mandatory for the etiologic diagnosis of inborn errors of dopamine and serotonin metabolism.
Guibal Pierre+3 more
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