Results 21 to 30 of about 1,595 (174)
Pterin determination in cerebrospinal fluid: state of the art
Pteridines, 2017 The analysis of pterins in the cerebrospinal fluid (CSF) is mandatory for the etiologic diagnosis of inborn errors of dopamine and serotonin metabolism.
Guibal Pierre +3 more
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Journal of Biological Chemistry, 1972 Abstract Qualitative and quantitative analyses for pterins (derivatives of 2-amino-4-hydroxypteridine) in human urine were carried out by an improved procedure which involved the use of two new weak ion exchangers, ECTEOLA-Sephadex and phospho-Sephadex.
T, Fukushima, T, Shiota
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Pteridines, 1999 A series of new 6-substituted 2,4-diaminopteridines (3-23) and pterins (26-43) have been synthesized by nucleophilic displacement reactions at the side chain of 6-bromomethyl-2,4-diaminopteridine (2) and 6- bromomethylpterin (25) using various types of 0-
Traub Hermann, Pfleiderer Wolfgang
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Exploring the scope of DBU-promoted amidations of 7-methoxycarbonylpterin
Beilstein Journal of Organic Chemistry, 2020 The synthetic utility of pterins is often hampered by the notorious insolubility of this heterocycle, slowing the development of medicinally relevant pteridine derivatives.
Anna R. Bockman, Jeffrey M. Pruet
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Journal of Biological Chemistry, 1959 Publisher Summary This chapter describes the bacterial pterin deaminase. In the standard assay, the mixture contains 0.05 ml of pterin carboxylic acid, 0.8 ml of phosphate buffer, and 0.02 to 0.15 ml of enzyme in a final volume of 1.0 ml. Incubation is carried out at 23° in a 1-ml Beckman quartz cuvette with a light path of 1.00 cm. Reaction is begun
B, LEVENBERG, O, HAYAISHI
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CSF Amino Acids, Pterins and Mechanism of the Ketogenic Diet
Pediatric Neurology Briefs, 2015 Investigators from Hospital Sant Joan de Deu, Barcelona, Spain, studied the relationship between the etiology of refractory childhood epilepsy, CSF neurotransmitters, pterins, and amino acids, and response to a ketogenic diet in 60 patients with ...
J. Gordon Millichap
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Molecules, 2019 Urinary pterins have been found as potential biomarkers in many pathophysiological conditions including inflammation, viral infections, and cancer. However, pterins determination in biological samples is difficult due to their degradation under exposure ...
Wojciech Grochocki +3 more
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Tryptophan oxidation photosensitized by pterin
Free Radical Biology and Medicine, 2013 Pterins are normal components of cells and they have been previously identified as good photosensitizers under UV-A irradiation, inducing DNA damage and oxidation of nucleotides. In this work, we have investigated the ability of pterin (Ptr), the parent compound of oxidized pterins, to photosensitize the oxidation of another class of biomolecules ...
Thomas, Andrés +6 more
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7‐Substituted pterins in humans with suspected pterin‐4a‐carbinolamine dehydratase deficiency [PDF]
European Journal of Biochemistry, 1992 A recently described new form of hyperphenylalaninemia is characterized by the excretion of 7‐substituted isomers of biopterin and neopterin and 7‐oxo‐biopterin in the urine of patients. It has been shown that the 7‐substituted isomers of biopterin and neopterin derive from L‐tetrahydrobiopterin and D‐tetrahydroneopterin and are formed during ...
Adler, Carmen +7 more
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BMC Cardiovascular Disorders, 2018 Background Development of collateral circulation in coronary artery disease is cardio-protective. A key process in forming new blood vessels is attraction to occluded arteries of monocytes with their subsequent activation as macrophages. In patients from
Edward C. A. Marks +16 more
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