Results 21 to 30 of about 4,628 (262)

The urinary biopterin in autism spectrum disorder

Pteridines, 2021
The aim of the study was to determine whether biopterin is present in significantly lower quantities in urine samples of patients with autism spectrum disorder (ASD) compared to healthy individuals.
Waligóra Aleksandra, Damasiewicz-Bodzek Aleksandra, Gorczyca Piotr, Waligóra Sławomir, Tyrpień-Golder Krystyna   +4 more
doaj   +1 more source

Antitumor activity of a pterin deaminase.

Agricultural and Biological Chemistry, 1979
Hitoshi Kusakabe, Kenjiro Kodama, Haruhiko Machida, Akira Kuninaka   +3 more
openaire   +3 more sources

Comparative routes to 7-carboxymethyl-pterin: A useful medicinal chemistry building block

Pteridines, 2022
Pterins, such as folate and biopterin, and their derivatives hold significant importance given their biological relevance, as well as the numerous pterin-based inhibitors developed for targeting various biological targets. For this reason, pterins can be
Bennett Zachary, Grumbles Kassidy, Pruet Jeffrey   +2 more
doaj   +1 more source

Modulation of Free Radical Formation by Pterin Derivatives

Pteridines, 2004
All classes of pterins, fully reduced tetrahydropterins, aromatic pterins and dihydropterins have been investigated upon their effects on radical mediated reactions.
Karl Oettl, Greilberger Joachim, Reibnegger Gilbert   +2 more
doaj   +1 more source

Orientation of Pterin-6-Carboxylic Acid on Gold Capped Silicon Nanopillars Platforms: Surface Enhanced Raman Spectroscopy and Density Functional Theory Studies [PDF]

, 2015
The orientation of pterin-6-carboxylic acid on gold nanopillars was investigated by surface enhanced Raman spectroscopy and density functional theory methods.
Bertel, Linda, Boisen, Anja, Castillo, John J., Martinez Ortega, Fernando, Mendez-Sanchez, Stelia C., Rindzevicius, Tomas, Rozo, Ciro E.   +6 more
core   +1 more source

Cerebrospinal Fluid Pterins, Pterin-Dependent Neurotransmitters, and Mortality in Pediatric Cerebral Malaria

The Journal of Infectious Diseases, 2021
Abstract Background Cerebral malaria (CM) pathogenesis remains incompletely understood. Having shown low systemic levels of tetrahydrobiopterin (BH4), an enzymatic cofactor for neurotransmitter synthesis, we hypothesized that BH4 and BH4-dependent neurotransmitters would likewise be low in ...
Matthew P Rubach, Jackson P Mukemba, Salvatore M Florence, Bert K Lopansri, Keith Hyland, Ryan A Simmons, Charles Langelier, Sara Nakielny, Joseph L DeRisi, Tsin W Yeo, Nicholas M Anstey, J Brice Weinberg, Esther D Mwaikambo, Donald L Granger   +13 more
openaire   +5 more sources

Structure of the first representative of Pfam family PF04016 (DUF364) reveals enolase and Rossmann-like folds that combine to form a unique active site with a possible role in heavy-metal chelation. [PDF]

, 2010
The crystal structure of Dhaf4260 from Desulfitobacterium hafniense DCB-2 was determined by single-wavelength anomalous diffraction (SAD) to a resolution of 2.01 Å using the semi-automated high-throughput pipeline of the Joint Center for Structural ...
Abdubek, Polat, Aravind, L, Astakhova, Tamara, Axelrod, Herbert L, Bakolitsa, Constantina, Carlton, Dennis, Chiu, Hsiu Ju, Clayton, Thomas, Deacon, Ashley M, Deller, Marc C, Duan, Lian, Elsliger, Marc André, Feuerhelm, Julie, Godzik, Adam, Grant, Joanna C, Han, Gye Won, Hodgson, Keith O, Jaroszewski, Lukasz, Jin, Kevin K, Klock, Heath E, Knuth, Mark W, Kozbial, Piotr, Krishna, S Sri, Kumar, Abhinav, Lesley, Scott A, Marciano, David, McMullan, Daniel, Miller, Mitchell D, Morse, Andrew T, Nigoghossian, Edward, Okach, Linda, Reyes, Ron, Rife, Christopher L, van den Bedem, Henry, Weekes, Dana, Wilson, Ian A, Wooley, John, Xu, Qingping   +37 more
core   +3 more sources

Pterins in Human Urine

Journal of Biological Chemistry, 1972
Abstract Qualitative and quantitative analyses for pterins (derivatives of 2-amino-4-hydroxypteridine) in human urine were carried out by an improved procedure which involved the use of two new weak ion exchangers, ECTEOLA-Sephadex and phospho-Sephadex.
T, Fukushima, T, Shiota
openaire   +2 more sources

Pterin determination in cerebrospinal fluid: state of the art

Pteridines, 2017
The analysis of pterins in the cerebrospinal fluid (CSF) is mandatory for the etiologic diagnosis of inborn errors of dopamine and serotonin metabolism.
Guibal Pierre, Lo Aurélien, Maitre Philippe, Moussa Fathi   +3 more
doaj   +1 more source

Exploring the scope of DBU-promoted amidations of 7-methoxycarbonylpterin

Beilstein Journal of Organic Chemistry, 2020
The synthetic utility of pterins is often hampered by the notorious insolubility of this heterocycle, slowing the development of medicinally relevant pteridine derivatives.
Anna R. Bockman, Jeffrey M. Pruet
doaj   +1 more source