Results 61 to 70 of about 1,595 (174)
Inactivation of tyrosinase photoinduced by pterin
Tyrosinase catalyzes in mammals the first and rate-limiting step in the biosynthesis of the melanin, the main pigment of the skin. Pterins, heterocyclic compounds able to photoinduce oxidation of DNA and its components, accumulate in the skin of patients suffering from vitiligo, a chronic depigmentation disorder in which the protection against UV ...
Dantola, Maria Laura +2 more
openaire +3 more sources
The Lrs14‐Like AbfR1 Homolog From Metallosphaera sedula Is a Nucleoid‐Organizing Protein
Nucleoid organization in Crenarchaeota involves diverse small DNA‐binding proteins. The Lrs14‐type protein AbfR1 from Metallosphaera sedula binds nonsequence specifically across the genome and induces DNA condensation. These findings suggest a structural role for AbfR1Ms in chromatin architecture, functionally resembling bacterial nucleoid‐associated ...
Veerke De Kock +5 more
wiley +1 more source
Degeneration of Rat Retina is Paralleled by an Imbalance of the Redox Mechanism of Pteridines
The RCS rat suffers from a genetic degeneration of retinal cell We have examined the pattern of oxidized and reduced monapterin and biopterin in retinas from RCS retinas and controls.
Cremer-Bartels Gertrud
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Read the free Plain Language Summary for this article on the Journal blog. Abstract Animal coloration serves a variety of visually related functions in nature (e.g. mate choice, aposematism and camouflage) but the pigments in integumentary tissues such as skin, scales and feathers may also serve functions unrelated to the visual environment (e.g ...
Beth A. Reinke +2 more
wiley +1 more source
Pterin Metabolism In Haemodialysis Patients
Patients undertaking maintenance haemodialysis may develop a variety of neurological disorders, the most serious of which is aluminium induced encephalopathy.
Altmann Paul +5 more
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Characterization of Underivatized Pterins by Laser Desorption Fourier Transfonn Mass Spectrometry
Laser desorption FfMS provides a powerful method for examining the structures of underivatized pteridines. (M + Na)+ and (M + K)+ ions are generated by laser desorption and can be used to determine molecular weights. The negative ion spectra provide more
Jacobson K. Bruce, Hettich Robert L.
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Mechanistic Study of ROS-photogeneration by Pterin
Pterins are widespread in biological systems and possess photosensitizing activities. In the present study, the photosensitization mechanism of acid form of pterin (PTA) and basic form of pterin (PTB) is investigated by means of density functional theory
Ji Hong-Fang, Shen Liang
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Neopterin, 7,8-dihydroneopterin and 5,6,7,8-terahydroneopterm are secreted by human macrophages after activation by interferon-γ. The biological stability of the reduced pterins is less than one hour and therefore distinctly lower than that of neopterin.
Horejsi Renate +3 more
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Nonribosomal peptides represent a large class of metabolites with pharmaceutical relevance. Pteridines, such as pterins, folates, and flavins, are heterocyclic metabolites that often serve as redox-active cofactors.
Hyun Bong Park +4 more
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Theoretical study on the relative energies of cationic pterin tautomers
Pterins are heterocyclic molecules of biological importance that contain several basic sites. These molecules can be protonated in aqueous solution resulting in a wide variety of structures that differ in their site of protonation and tautomeric form. In
Nekkanti Sindhura, Martin Christopher B.
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