Results 61 to 70 of about 4,302 (241)

Diagnosis of tetrahydrobiopterin deficiency using filter paper blood spots: further development of the method and 5 years experience [PDF]

open access: yes, 2018
In every newborn with even mild hyperphenylalaninemia (HPA) tetrahydrobiopterin (BH4) deficiencies need to be excluded as soon as possible. Differential diagnosis is most commonly performed by analysis of urinary neopterin and biopterin.
Abu Seda, Bettina   +5 more
core  

HR‐MS Analysis of the Covalent Binding of Edaravone to 5‐Formylpyrimidine Bases and a DNA Oligonucleotide Containing a 5‐Formylcytidine Residue

open access: yesRapid Communications in Mass Spectrometry, Volume 39, Issue 14, 30 July 2025.
ABSTRACT Rationale Edaravone (EDA) is a radical scavenger and an antioxidant drug approved to treat amyotrophic lateral sclerosis and used as a research tool to explore treatment of neurodegenerative diseases and cancers. It is also a reactive agent, known as PMP (1‐phenyl‐3‐methyl‐5‐pyrazolone), used for the analysis of polysaccharides composition ...
Romain Regnault   +5 more
wiley   +1 more source

Ultraviolet-induced fluorescent imaging for millipede taxonomy [PDF]

open access: yesResearch Ideas and Outcomes, 2017
Fluorescent imaging has been traditionally applied to cell biology, and more recently to entomology to capture microscopic images of insect anatomy. However, the technique has not been applied to the study of millipedes, most of which autofluoresce as a ...
Paul Marek
doaj   +2 more sources

Tetrahydrobiopterin Deficiency: From Phenotype to Genotype [PDF]

open access: yes, 2017
As a result of the selective screening worldwide during the last 18 years, approximately 250 patients with tetrahydrobiopterin deficiency were discovered.
Blau, Nenad   +3 more
core  

The compositional and evolutionary logic of metabolism

open access: yes, 2012
Metabolism displays striking and robust regularities in the forms of modularity and hierarchy, whose composition may be compactly described. This renders metabolic architecture comprehensible as a system, and suggests the order in which layers of that ...
Alberts B   +75 more
core   +1 more source

Mechanism of photooxidation of folic acid sensitized by unconjugated pterins [PDF]

open access: yes, 2010
Folic acid, or pteroyl-L-glutamic acid (PteGlu), is a precursor of coenzymes involved in the metabolism of nucleotides and amino acids. PteGlu is composed of three moieties: a 6-methylpterin (Mep) residue, a p-aminobenzoic acid (PABA) residue, and a ...
Denofrio, María Paula   +6 more
core   +1 more source

The Encapsulation Strategies for Targeted Delivery of Probiotics in Preventing and Treating Colorectal Cancer: A Review

open access: yesAdvanced Science, Volume 12, Issue 18, May 15, 2025.
This work summarizes the efficacy and mechanisms of probiotics in CRC treatment, providing a comprehensive overview of various encapsulation methods such as microcapsules, hydrogels, single‐cell nanocoatings, and nanofibers for targeted probiotic delivery to inflammatory sites, with particular emphasis on the potential advantages of emerging single ...
Hao Zhong   +5 more
wiley   +1 more source

Investigation of Spectra and Ionization Constants of 8-Alkyl Pterins by Fluorimetry

open access: yesPteridines, 1993
Spectrofluorimetric studies of the properties of 8-alkyl-pterins arc reported, together with preliminary results on the use of fluorimetry in studying the binding of these new mechanism-based substrates to dihydrofolate reductase (DHFR).
Jeong Soon-Seog   +2 more
doaj   +1 more source

Pterins as Sensors of Response to the Application of Fe3+-Dextran in Piglets

open access: yesSensors, 2010
The aim of the presented study was to assess the effect of a single administration of Fe3+-dextran on immune cell counts and pterin biomolecule production as novel sensors of the piglets' immune system activation, and to determine concentrations of ...
Klara Breinekova   +2 more
doaj   +1 more source

Detection of pterins and enzymatic activities of GTP-cyclohydrolase I and sepiapterin reductase in Neurospora crassa and Phycomyces blakesleeanus [PDF]

open access: yes, 1993
The best known pterin in Neurospora crassa is molybdopterin, which is a constituent of the flavohemoenzyme nitrate reductase and participates in blue-light promoted conidiation (Klemm and Ninnemann 1979 ...
Maier, J., Ninnemann, H.
core   +2 more sources

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